CUSIP: 004468500 | NYSE | Healthcare · Biotechnology | Micro Cap | 233 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13GVivo Opportunity, LLC with Vivo Opportunity Co-Invest (Cycle 3), L.P., Vivo Opportunity Fund Holdings, L.P., Vivo Opportunity Co-Invest, L.P., +2 more | 5,305,640 | 5.0% | New 5%+ stake | Jul 6, 2026 | No 13F filer matched |
| 13G/AFranklin Advisers, Inc. with Charles B. Johnson, Rupert H. Johnson, Jr. | 8,878,942 | 8.3% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13GHenderson Group PLC | 5,502,064 | 5.4% | New 5%+ stake | Jun 30, 2026 | Not yet in a 13F |
| 13GLogos Global Management LP with Logos Opportunities V GP LLC, Logos Opportunities Fund V LP, Graham Walmsley, +2 more | 10,538,440 | 10.0% | New 5%+ stake | May 11, 2026 | No 13F filer matched |
| 13DvenBio Global Strategic Fund V, L.P. | 10,737,317 | 10.0% | New 5%+ stake | Apr 15, 2026 | No 13F filer matched |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 932,105 | $7.5M | 0.1% | Core | Low | Las Vegas, NV | 2026-10-27 | |
| 753,900 | $6.1M | 0.0% | Core | Low | New York, NY | 2026-11-05 | |
| 85,888 | $694.8K | 0.0% | ETF | Low | Brentwood, TN | 2026-10-15 | |
| 74,550 | $509.2K | 0.0% | Core | Medium | Dallas, TX | 2026-11-04 | |
| 67,177 | $543.5K | 0.1% | ETF | Medium | Westlake Village, CA | 2026-10-15 | |
| 66,763 | $483.4K | 0.2% | ETF | Low | Media, PA | 2026-10-20 | |
| 40,578 | $328.3K | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 32,353 | $261.7K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 25,000 | $202.3K | 0.0% | ETF | Medium | San Francisco, CA | 2026-10-16 | |
| 15,319 | $123.9K | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 14,965 | $121.1K | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 11,000 | $89.0K | 0.1% | Growth | Medium | Scottsdale, AZ | 2026-10-15 | |
| 10,817 | $87.5K | 0.0% | ETF | Very Low | Phoenix, AZ | 2026-10-13 | |
| 10,000 | $80.9K | 0.1% | ETF | Medium | Seattle, WA | 2026-10-28 | |
| 2,553 | $20.7K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 2,206 | $17.8K | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-10-29 | |
| 811 | $6.6K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 500 | $4 | 0.0% | ETF | Low | The Woodlands, TX | 2026-11-04 | |
| 212 | $1.7K | 0.0% | GARP | Low | Phoenix, AZ | 2026-10-02 | |
| 195 | $1.6K | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 150 | $1.2K | 0.0% | Growth | Medium | Palm Beach Gardens, FL | 2026-10-19 | |
| 84 | $680 | 0.0% | Index | Low | San Francisco, CA | 2026-11-03 | |
| 29 | $235 | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 14 | $113 | 0.0% | Core | Medium | Orchard Park, NY | 2026-11-05 | |
| 8 | $65 | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 |