CUSIP: 00461U105 | NYSE | Healthcare · Biotechnology | Small Cap | 499 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13GFrazier Life Sciences Public Fund, L.P. with Fhmls XII, L.L.C., Frazier Life Sciences XII, L.P., Fhmls XII, L.P., +3 more | 7,879,943 | 5.4% | New 5%+ stake | Sep 14, 2026 | No 13F filer matched |
| 13G/ARA Capital Management, L.P. | 12,723,026 | 9.1% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 513,840 | $2.7M | 0.0% | Index | Low | Austin, TX | 2026-11-04 | |
| 277,694 | $1.5M | 0.0% | Core | Low | New York, NY | 2026-11-05 | |
| 258,367 | $1.4M | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 195,036 | $1.0M | 0.0% | Yield | Low | Denver, CO | 2026-11-03 | |
| 171,421 | $901.7K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 154,554 | $813.0K | 0.0% | Growth | High | Senningerberg, Netherlands | 2026-10-15 | |
| 119,200 | $627.0K | 0.0% | Core | Medium | Columbus, OH | 2026-10-30 | |
| 80,090 | $421.3K | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 43,328 | $228.0K | 0.0% | ETF | Low | Fairfield, IA | 2026-11-02 | |
| 26,858 | $141.8K | 0.0% | Growth | Medium | Shanghai, France | 2026-10-28 | |
| 19,983 | $105.1K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 18,790 | $98.8K | 0.0% | Core | Medium | Zurich, Switzerland | 2026-10-16 | |
| 17,782 | $93.5K | 0.0% | ETF | Very Low | Northfield, NJ | 2026-10-16 | |
| 15,759 | $82.9K | 0.0% | Value | Very High | Hong Kong, South Korea | 2026-10-16 | |
| 13,006 | $68.4K | 0.0% | Core | Low | Des Moines, IA | 2026-11-02 | |
| 11,077 | $58.3K | 0.0% | Index | Very Low | Philadelphia, PA | 2026-11-03 | |
| 10,000 | $52.6K | 0.0% | ETF | Very Low | Tomah, WI | 2026-10-26 | |
| 9,131 | $48.0K | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-10-29 | |
| 7,522 | $39.6K | 0.0% | Growth | Low | Seoul, Malaysia | 2026-11-03 | |
| 6,091 | $32.0K | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 | |
| 3,657 | $19.2K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 2,779 | $14.6K | 0.0% | Agg Growth | Medium | Guangzhou, France | 2026-10-26 | |
| 1,856 | $9.8K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 560 | $2.9K | 0.0% | ETF | Very Low | Sylvania, OH | 2026-10-26 | |
| 500 | $2.6K | 0.0% | ETF | Low | Bethlehem, PA | 2026-10-23 | |
| 454 | $2 | 0.0% | ETF | Low | Shaker Heights, OH | 2026-10-27 | |
| 433 | $2.3K | 0.0% | Growth | Low | St Louis, MO | 2026-11-05 | |
| 391 | $2.1K | 0.0% | Core | Low | Springfield, MA | 2026-10-05 | |
| 357 | $1.9K | 0.0% | Index | Low | San Francisco, CA | 2026-11-03 | |
| 318 | $1.7K | 0.0% | Index | Very Low | St. Louis, MO | 2026-10-20 | |
| 255 | $1.3K | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 230 | $1.2K | 0.0% | Growth | Low | Tampa, FL | 2026-10-16 | |
| 80 | $421 | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 68 | $358 | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 56 | $295 | 0.0% | ETF | Medium | Scottsdale, AZ | 2026-10-14 | |
| 32 | $168 | 0.0% | ETF | Medium | Encinitas, CA | 2026-10-21 | |
| 5 | $26 | 0.0% | Value | Medium | Rancho Santa Fe, CA | 2026-10-14 |