CUSIP: 008064206 | NYSE | Healthcare · Biotechnology | Small Cap | 196 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13GFranklin Templeton, Inc. with Rupert H. Johnson, Jr., Charles B. Johnson | 3,807,236 | 6.0% | New 5%+ stake | Sep 30, 2026 | No 13F filer matched |
| 13GBlackRock, Inc. | 3,323,301 | 5.2% |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 1,205,972 | $16.9M | 0.0% | Growth | Medium | Carouge, Switzerland | 2026-11-03 | |
| 88,786 | $1.2M | 0.0% | Core | Low | Des Moines, IA | 2026-11-02 | |
| 33,298 | $467.8K | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 26,008 | $365.4K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 14,808 | $208.1K | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 13,755 | $193.3K | 0.0% | Core | Low | Trenton, NJ | 2026-11-05 | |
| 11,993 | $168.5K | 0.0% | Index | Very Low | Phoenix, AZ | 2026-11-03 | |
| 2,110 | $29.6K | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 | |
| 1,604 | $22.5K | 0.0% | Index | Very Low | St. Louis, MO | 2026-10-20 | |
| 1,324 | $18.6K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 1,257 | $17.7K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 1,189 | $16.7K | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-10-29 | |
| 905 | $12.7K | 0.0% | GARP | Low | Phoenix, AZ | 2026-10-02 | |
| 806 | $11.3K | 0.0% | Value | High | Cheyenne, WY | 2026-10-28 | |
| 732 | $10.3K | 0.0% | Index | Low | Atlanta, GA | 2026-10-23 | |
| 112 | $1.6K | 0.0% | ETF | Very Low | Redwood City, CA | 2026-11-02 | |
| 103 | $1.4K | 0.0% | Growth | Low | St Louis, MO | 2026-11-05 | |
| 55 | $773 | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 32 | $450 | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 30 | $422 | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 28 | $393 | 0.0% | ETF | Medium | Scottsdale, AZ | 2026-10-14 | |
| 10 | $0 | 0.0% | Value | High | London, United Kingdom | 2026-10-30 | |
| 7 | $98 | 0.0% | Growth | Low | Tampa, FL | 2026-10-16 | |
| 7 | $99 | 0.0% | Index | Low | Greenwood Village, CO | 2026-10-20 | |
| 6 | $0 | 0.0% | ETF | Low | Shaker Heights, OH | 2026-10-27 | |
| 4 | $56 | 0.0% | Value | Medium | Rancho Santa Fe, CA | 2026-10-14 | |
| 4 | $56 | 0.0% | Core | Medium | Orchard Park, NY | 2026-11-05 | |
| 3 | $43 | 0.0% | ETF | Very Low | Boston, MA | 2026-10-26 | |
| 2 | $28 | 0.0% | ETF | Low | Herndon, VA | 2026-10-30 | |
| 2 | $28 | 0.0% | ETF | Medium | Encinitas, CA | 2026-10-21 | |
| 1 | $14 | 0.0% | Agg Growth | Low | Dallas, TX | 2026-11-03 | |
| 1 | $14 | 0.0% | ETF | Low | Concord, CA | 2026-10-21 | |
| 1 | $15 | 0.0% | ETF | Very Low | Sylvania, OH | 2026-10-26 |
| New 5%+ stake |
| Sep 30, 2026 |
| 92d ahead of 13F (2,801,451 sh) · +521,850 |
| 13GParadigm BioCapital Advisors GP LLC with Paradigm BioCapital International Fund Ltd. | 3,106,793 | 5.1% | New 5%+ stake | Jul 10, 2026 | No 13F filer matched |
| 13G/AHenderson Group PLC | 6,273,262 | 10.6% | New 5%+ stake | Jun 30, 2026 | 91d ahead of 13F (3,105,669 sh) · +3,167,593 |
| 13G/AVenrock Healthcare Capital Partners III, L.P. | 5,145,330 | 8.3% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13G/ABellevue Asset Management AG | 3,057,996 | 5.0% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13D/ASofinnova Venture Partners X, L.P. ("svp X") | 107,391 | 0.3% | Newly reported | Apr 28, 2025 | No 13F filer matched |