CUSIP: 019770106 | NYSE | Healthcare · Biotechnology | Small Cap | 598 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13G/ABlackRock, Inc. | 23,211,736 | 6.7% | New 5%+ stake | Sep 30, 2026 | 92d ahead of 13F (30,146,963 sh) · −6,935,227 |
| 13D/ATPG GP A, LLC | 0 | 0.0% | No shares held | Sep 28, 2026 | 90d ahead of 13F (18,716,306 sh) · −18,716,306 |
| 13G/AFrazier Life Sciences Public Fund, L.P. with Frazier Life Sciences XII, L.P., Fhmls XII, L.P., Fhmls XII, L.L.C., +8 more | 19,445,046 | 5.6% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13G/AArie Belldegrun, M.D. with Bellco Legacy IV LLC, Vida Ventures LLC, Vida Ventures III, L.P., +2 more | 13,610,578 | 3.9% | Newly reported | Jun 30, 2026 | No 13F filer matched |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 5,422,820 | $8.7M | 0.0% | Growth | Medium | Strassen, Netherlands | 2026-11-03 | |
| 3,202,488 | $5.1M | 0.0% | Index | Low | Austin, TX | 2026-11-04 | |
| 2,920,787 | $4.7M | 2.7% | GARP | Very Low | New York, NY | 2026-10-28 | |
| 1,100,000 | $1.8M | 0.0% | Growth | Medium | Vienna, Chile | 2026-10-28 | |
| 1,039,328 | $1.7M | 0.0% | Value | Medium | Parsippany, NJ | 2026-10-13 | |
| 546,210 | $873.9K | 0.0% | Index | Very Low | Tokyo, Mexico | 2026-11-05 | |
| 454,472 | $727.2K | 0.0% | Yield | Low | Denver, CO | 2026-11-03 | |
| 453,806 | $726.1K | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 308,864 | $494.2K | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 281,434 | $450.3K | 0.2% | Growth | Low | Los Angeles, CA | 2026-10-29 | |
| 279,259 | $446.8K | 0.0% | Growth | Very Low | Seattle, WA | 2026-10-27 | |
| 174,258 | $278.8K | 0.0% | Growth | Low | Atlanta, GA | 2026-10-21 | |
| 147,000 | $235.2K | 0.0% | Growth | Medium | Clearwater, FL | 2026-10-26 | |
| 141,379 | $226.2K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 137,212 | $219.5K | 0.0% | Index | Low | Rockford, IL | 2026-10-28 | |
| 63,039 | $102.1K | 0.0% | Growth | Medium | Shanghai, France | 2026-10-28 | |
| 48,000 | $76.8K | 0.0% | Core | Medium | Darien, CT | 2026-10-19 | |
| 45,303 | $72.5K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 40,000 | $64.0K | 0.0% | Core | Medium | Zurich, Switzerland | 2026-10-16 | |
| 31,015 | $43.4K | 0.0% | Core | Low | Plymouth, MN | 2026-10-13 | |
| 24,992 | $40.0K | 0.0% | Core | Medium | Baton Rouge, LA | 2026-10-19 | |
| 24,874 | $39.8K | 0.0% | Index | Very Low | Philadelphia, PA | 2026-11-03 | |
| 21,000 | $33.6K | 0.0% | Core | Low | Chapel Hill, NC | 2026-11-03 | |
| 20,000 | $32.0K | 0.0% | ETF | Low | El Segundo, CA | 2026-10-23 | |
| 17,655 | $28.2K | 0.0% | Growth | Low | Seoul, Malaysia | 2026-11-03 | |
| 16,529 | $26.4K | 0.0% | Core | Medium | Redondo Beach, CA | 2026-10-21 | |
| 16,219 | $26.0K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 15,750 | $25.0K | 0.0% | Core | Medium | New York, NY | 2026-10-20 | |
| 14,313 | $22.9K | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-10-29 | |
| 13,402 | $21.4K | 0.0% | Core | Low | Des Moines, IA | 2026-11-02 | |
| 13,357 | $21.4K | 0.0% | Core | Very Low | Seattle, WA | 2026-11-03 | |
| 11,500 | $18.4K | 0.0% | Core | Low | New York, NY | 2026-10-26 | |
| 10,640 | $17.0K | 0.0% | ETF | Medium | Los Angeles, CA | 2026-10-22 | |
| 10,000 | $16.0K | 0.0% | Growth | Low | Marion, MA | 2026-10-13 | |
| 7,431 | $11.9K | 0.0% | Agg Growth | Medium | Guangzhou, France | 2026-10-26 | |
| 6,904 | $11.0K | 0.0% | Index | Low | Atlanta, GA | 2026-10-23 | |
| 5,117 | $8.2K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 2,431 | $3.9K | 0.0% | Core | Very High | Chicago, IL | 2026-11-04 | |
| 2,000 | $3.2K | 0.0% | ETF | Very Low | Manhattan, KS | 2026-10-09 | |
| 1,198 | $1.9K | 0.0% | Index | Low | San Francisco, CA | 2026-11-03 | |
| 1,044 | $1.7K | 0.0% | ETF | Medium | Scottsdale, AZ | 2026-10-14 | |
| 1,028 | $1.6K | 0.0% | Index | Very Low | St. Louis, MO | 2026-10-20 | |
| 780 | $1.2K | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 613 | $981 | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 551 | $882 | 0.0% | Growth | Low | Los Angeles, CA | 2026-10-23 | |
| 486 | $778 | 0.0% | ETF | Very Low | Orinda, CA | 2026-10-29 | |
| 450 | $720 | 0.0% | ETF | Medium | Midvale, UT | 2026-10-20 | |
| 351 | $562 | 0.0% | Core | High | Zurich, Switzerland | 2026-10-29 | |
| 178 | $285 | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 | |
| 167 | $267 | 0.0% | Growth | Low | Tampa, FL | 2026-10-16 | |
| 159 | $255 | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 73 | $0 | 0.0% | Value | High | London, United Kingdom | 2026-10-30 | |
| 20 | $32 | 0.0% | ETF | Low | Eagle, ID | 2026-10-13 |