CUSIP: 02157Q109 | NYSE | Healthcare · Biotechnology | Small Cap | 210 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13GVanguard Capital Management LLC | 1,970,108 | 5.0% | New 5%+ stake | Sep 30, 2026 | 92d ahead of 13F (1,389,477 sh) · +580,631 |
| 13GEcoR1 Capital, LLC with EcoR1 Capital Fund Qualified, L.P. |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 78,292 | $2.0M | 0.0% | Index | Low | Austin, TX | 2026-11-04 | |
| 51,971 | $1.3M | 0.0% | Yield | Low | Denver, CO | 2026-11-03 | |
| 37,885 | $967.2K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 19,577 | $499.8K | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 14,175 | $361.9K | 0.0% | Core | High | Austin, TX | 2026-11-03 | |
| 13,180 | $336.5K | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 13,000 | $308.6K | 0.1% | Core | Low | Akron, OH | 2026-10-20 | |
| 10,171 | $259.7K | 0.0% | Core | Very High | Chicago, IL | 2026-11-04 | |
| 6,500 | $165.9K | 0.1% | GARP | Very High | Reno, NV | 2026-10-09 | |
| 5,355 | $136.7K | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 2,315 | $59.1K | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 | |
| 1,400 | $35.7K | 0.0% | Core | Medium | Columbus, OH | 2026-10-30 | |
| 1,317 | $33.6K | 0.0% | Value | High | Cheyenne, WY | 2026-10-28 | |
| 1,054 | $26.9K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 453 | $11.6K | 0.0% | Index | Very Low | St. Louis, MO | 2026-10-20 | |
| 409 | $10.4K | 0.0% | ETF | Medium | San Diego, CA | 2026-10-29 | |
| 292 | $7.5K | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-10-29 | |
| 270 | $6.9K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 121 | $3.1K | 0.0% | Core | Low | Springfield, MA | 2026-10-05 | |
| 98 | $2.5K | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 81 | $2.1K | 0.0% | ETF | Medium | Scottsdale, AZ | 2026-10-14 | |
| 40 | $1.0K | 0.0% | Index | Low | Atlanta, GA | 2026-10-23 | |
| 33 | $842 | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 4 | $103 | 0.0% | ETF | Very Low | Sylvania, OH | 2026-10-26 |
| 2,232,000 |
| 5.8% |
| New 5%+ stake |
| Jul 13, 2026 |
| No 13F filer matched |
| 13G/APerceptive Advisors LLC | 4,176,711 | 10.0% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13G/ASirenia Capital Management LP | 2,219,568 | 6.2% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13G/AVestal Point Capital, LP | 785,000 | 2.2% | Newly reported | Jun 30, 2026 | No 13F filer matched |