CUSIP: 03969K108 | NYSE | Healthcare · Biotechnology | Mid Cap | 591 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13G/ABlackRock, Inc. | 17,751,435 | 14.1% | New 5%+ stake | Sep 30, 2026 | 10,545,466 sh (Jun 30, 2026) |
| 13GPolar Capital Holdings Plc | 6,606,945 | 5.3% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 1,003,729 | $26.6M | 0.1% | Growth | Medium | Strassen, Netherlands | 2026-11-03 | |
| 958,843 | $25.3M | 0.4% | Value | Medium | Sydney, New South Wales, China | 2026-10-13 | |
| 865,862 | $22.9M | 0.4% | Core | Low | Las Vegas, NV | 2026-10-27 | |
| 803,525 | $21.2M | 0.0% | Core | Low | Des Moines, IA | 2026-11-02 | |
| 597,115 | $15.8M | 1.3% | Growth | Very Low | Troy, MI | 2026-10-26 | |
| 596,303 | $15.8M | 0.0% | Core | Low | New York, NY | 2026-11-05 | |
| 333,193 | $8.8M | 1.7% | Growth | Medium | Amsterdam, Philippines | 2026-11-03 | |
| 196,607 | $5.3M | 0.0% | Growth | Medium | Carouge, Switzerland | 2026-11-03 | |
| 196,072 | $5.2M | 0.1% | Core | Low | Shawnee Mission, KS | 2026-11-03 | |
| 187,000 | $4.9M | 1.7% | GARP | Medium | Pueblo, CO | 2026-10-26 | |
| 132,924 | $3.5M | 0.5% | Growth | Medium | Boston, MA | 2026-10-19 | |
| 98,236 | $2.6M | 0.1% | Core | Medium | London, United Kingdom | 2026-11-04 | |
| 87,442 | $2.3M | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 85,000 | $2.2M | 0.0% | Core | Medium | Zurich, Switzerland | 2026-10-16 | |
| 81,138 | $2.1M | 0.0% | GARP | Medium | Minneapolis, MN | 2026-11-05 | |
| 49,700 | $1.3M | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 48,700 | $1.3M | 0.0% | Index | Low | Baton Rouge, LA | 2026-10-20 | |
| 41,505 | $1.1M | 0.1% | Growth | Medium | Los Angeles, CA | 2026-10-20 | |
| 40,265 | $1.1M | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 36,357 | $960.9K | 0.0% | Core | Low | Trenton, NJ | 2026-11-05 | |
| 35,646 | $942.1K | 0.0% | Value | Very High | Greenwich, CT | 2026-11-02 | |
| 32,700 | $864.3K | 0.0% | Core | Medium | Richmond, VA | 2026-10-28 | |
| 31,716 | $838.3K | 0.0% | Index | Very Low | Phoenix, AZ | 2026-11-03 | |
| 30,552 | $807.5K | 0.0% | Growth | Low | Atlanta, GA | 2026-10-21 | |
| 30,493 | $805.9K | 0.0% | Core | Medium | Toronto Ontario, Australia | 2026-11-02 | |
| 30,489 | $805.8K | 0.0% | Index | Very Low | Bloomfield Hills, MI | 2026-10-22 | |
| 29,652 | $784.0K | 0.0% | Core | Very Low | New York, NY | 2026-10-23 | |
| 27,100 | $716.3K | 0.0% | Core | Medium | Columbus, OH | 2026-10-30 | |
| 26,949 | $712.3K | 0.0% | Core | Low | Harrisburg, PA | 2026-11-03 | |
| 26,934 | $720.5K | 0.0% | Growth | Medium | Shanghai, France | 2026-10-28 | |
| 25,700 | $679.3K | 0.0% | Index | Very Low | Tigard, OR | 2026-10-30 | |
| 25,514 | $674.3K | 0.0% | Index | Very Low | Baltimore, MD | 2026-11-05 | |
| 24,772 | $653.0K | 0.0% | Core | Very Low | Juneau, AK | 2026-10-15 | |
| 23,704 | $626.5K | 0.0% | GARP | High | Meridian, ID | 2026-10-22 | |
| 23,136 | $611.5K | 0.0% | Index | Very Low | Cincinnati, OH | 2026-11-05 | |
| 22,401 | $592.1K | 0.0% | Growth | High | Montreal, Austria | 2026-11-03 | |
| 20,045 | $529.8K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 19,258 | $509.0K | 0.4% | Value | Very High | Castle Rock, CO | 2026-11-04 | |
| 18,840 | $497.9K | 0.0% | Growth | Medium | Helsinki, Hungary | 2026-11-05 | |
| 16,196 | $428.1K | 0.3% | ETF | Low | Thousand Oaks, CA | 2026-10-14 | |
| 16,021 | $423.4K | 0.0% | Core | Low | Brooklyn, OH | 2026-11-04 | |
| 16,000 | $422.9K | 0.3% | Momentum | Medium | Forest, VA | 2026-10-28 | |
| 14,048 | $344.0K | 0.0% | Core | Low | Plymouth, MN | 2026-10-13 | |
| 13,051 | $344.9K | 0.0% | Index | Low | New York, NY | 2026-10-23 | |
| 12,182 | $322.0K | 0.0% | Value | High | Cheyenne, WY | 2026-10-28 | |
| 10,987 | $290.4K | 0.0% | Index | Very Low | Philadelphia, PA | 2026-11-03 | |
| 10,770 | $284.7K | 0.0% | Core | Low | Leesburg, VA | 2026-10-08 | |
| 10,000 | $264.3K | 0.2% | ETF | Medium | Las Vegas, NV | 2026-10-21 | |
| 9,500 | $251.0K | 0.0% | Momentum | Medium | London, United Kingdom | 2026-10-30 | |
| 8,729 | $230.7K | 0.0% | Growth | Low | Austin, TX | 2026-10-30 | |
| 6,471 | $171.0K | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-10-29 | |
| 6,423 | $169.8K | 0.0% | Growth | Low | Seoul, Malaysia | 2026-11-03 | |
| 4,376 | $116.0K | 0.0% | Core | Medium | Brussels, Czech Republic | 2026-10-22 | |
| 3,776 | $99.8K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 3,529 | $93.3K | 0.0% | Agg Growth | Medium | Guangzhou, France | 2026-10-26 | |
| 3,200 | $85.0K | 0.0% | Core | Very Low | Albany, NY | 2026-10-22 | |
| 2,553 | $67.5K | 0.0% | Growth | Medium | Mclean, VA | 2026-10-30 | |
| 2,137 | $56.5K | 0.0% | Index | Low | Atlanta, GA | 2026-10-23 | |
| 2,130 | $56.0K | 0.1% | Value | High | London, United Kingdom | 2026-10-30 | |
| 2,017 | $53.3K | 0.0% | ETF | Low | Concord, CA | 2026-10-21 | |
| 2,000 | $52.9K | 0.0% | Index | Low | Fort Worth, TX | 2026-11-05 | |
| 1,902 | $50.3K | 0.0% | Index | Very Low | St. Louis, MO | 2026-10-20 | |
| 1,365 | $36.1K | 0.0% | GARP | Low | Mansfield, OH | 2026-10-27 | |
| 1,337 | $35.3K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 1,239 | $32.7K | 0.0% | ETF | Very Low | Sylvania, OH | 2026-10-26 | |
| 1,000 | $26.4K | 0.0% | Growth | Medium | Yardley, PA | 2026-10-14 | |
| 900 | $23.8K | 0.0% | ETF | Medium | Denver, CO | 2026-10-14 | |
| 893 | $23.6K | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 736 | $19.5K | 0.0% | ETF | Very High | San Diego, CA | 2026-10-22 | |
| 711 | $18.8K | 0.0% | Value | Low | Plymouth, MA | 2026-11-04 | |
| 686 | $18.1K | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 | |
| 491 | $13.0K | 0.0% | ETF | Medium | Fort Myers, FL | 2026-10-28 | |
| 375 | $9.9K | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 358 | $9.5K | 0.0% | Value | Medium | Rancho Santa Fe, CA | 2026-10-14 | |
| 335 | $8 | 0.0% | ETF | Low | The Woodlands, TX | 2026-11-04 | |
| 325 | $8.6K | 0.0% | GARP | Very High | Reno, NV | 2026-10-09 | |
| 318 | $8.1K | 0.0% | Core | Low | Toronto, Australia | 2026-10-16 | |
| 224 | $5.9K | 0.0% | Index | Low | Minneapolis, MN | 2026-11-05 | |
| 187 | $4.9K | 0.0% | Growth | Low | St Louis, MO | 2026-11-05 | |
| 183 | $4.8K | 0.0% | Growth | Low | Tampa, FL | 2026-10-16 | |
| 176 | $4.7K | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 108 | $2.9K | 0.0% | GARP | Low | Phoenix, AZ | 2026-10-02 | |
| 104 | $2.7K | 0.0% | Core | Very Low | Lincoln, NE | 2026-10-22 | |
| 83 | $2.2K | 0.0% | ETF | Medium | Akron, OH | 2026-10-13 | |
| 71 | $1.9K | 0.0% | ETF | Low | Bethlehem, PA | 2026-10-23 | |
| 67 | $1.8K | 0.0% | Index | Low | San Francisco, CA | 2026-11-03 | |
| 55 | $1.5K | 0.0% | Index | Low | Greenwood Village, CO | 2026-10-20 | |
| 48 | $1.3K | 0.0% | Growth | N/A | Kansas City, MO | 2026-10-19 | |
| 48 | $1.3K | 0.0% | ETF | Medium | Scottsdale, AZ | 2026-10-14 | |
| 47 | $1.2K | 0.0% | ETF | Very Low | Gap, PA | 2026-11-04 | |
| 46 | $1.2K | 0.0% | ETF | Medium | Midvale, UT | 2026-10-20 | |
| 34 | $899 | 0.0% | ETF | Low | Fort Lauderdale, FL | 2026-10-30 | |
| 32 | $846 | 0.0% | ETF | Medium | Encinitas, CA | 2026-10-21 | |
| 22 | $581 | 0.0% | Core | Medium | Orchard Park, NY | 2026-11-05 | |
| 14 | $371 | 0.0% | ETF | Very Low | Hermitage, PA | 2026-11-03 | |
| 7 | $186 | 0.0% | Growth | Low | Denver, CO | 2026-10-09 | |
| 6 | $159 | 0.0% | Core | Low | Jacksonville, FL | 2026-10-08 | |
| 4 | $106 | 0.0% | ETF | Low | Hunt Valley, MD | 2026-10-23 | |
| 2 | $64 | 0.0% | ETF | Low | Herndon, VA | 2026-10-30 | |
| 1 | $27 | 0.0% | ETF | Very Low | Boston, MA | 2026-10-26 |