CUSIP: 04335A105 | NYSE | Healthcare · Biotechnology | Small Cap | 660 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13G/AD. E. Shaw & Co., L.P. with D. E. Shaw & Co., L.L.C. | 3,495,153 | 5.4% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| 13D/ALogos Global Management LP with Logos Global Master Fund LP, Logos GP LLC, Logos Opportunities Fund IV LP, +2 more | 2,500,000 | 3.4% | Newly reported | Oct 13, 2025 | 5,575,000 sh (Sep 30, 2025) |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 811,442 | $6.3M | 0.0% | Index | Low | Austin, TX | 2026-11-04 | |
| 686,074 | $5.3M | 0.0% | Core | Medium | Toronto Ontario, Australia | 2026-11-02 | |
| 248,390 | $1.9M | 0.0% | Core | Low | New York, NY | 2026-11-05 | |
| 108,900 | $842.3K | 0.0% | Core | Medium | Columbus, OH | 2026-10-30 | |
| 89,895 | $695.3K | 0.0% | Growth | Medium | New York, NY | 2026-10-16 | |
| 84,506 | $653.7K | 0.0% | Value | Very High | Hong Kong, South Korea | 2026-10-16 | |
| 76,112 | $588.7K | 0.0% | Growth | Low | Bethesda, MD | 2026-10-29 | |
| 68,456 | $529.5K | 0.0% | Growth | High | Senningerberg, Netherlands | 2026-10-15 | |
| 62,846 | $486.5K | 0.0% | Core | Medium | Zeist, Philippines | 2026-10-30 | |
| 57,500 | $444.8K | 0.1% | Agg Growth | High | Warsaw, Russia | 2026-11-05 | |
| 46,665 | $361.0K | 0.1% | GARP | Low | Tel Aviv, Luxembourg | 2026-10-26 | |
| 42,932 | $332.1K | 0.0% | Index | Very Low | Overland Park, KS | 2026-11-02 | |
| 41,893 | $324.0K | 0.0% | Value | High | Cheyenne, WY | 2026-10-28 | |
| 32,987 | $255.2K | 0.0% | Core | Medium | New York, NY | 2026-11-04 | |
| 32,121 | $248.5K | 0.2% | Core | High | San Juan, PR | 2026-11-03 | |
| 23,684 | $183.2K | 0.0% | Core | Low | Virginia Beach, VA | 2026-11-03 | |
| 17,712 | $137.0K | 0.0% | Core | Low | Trenton, NJ | 2026-11-05 | |
| 15,463 | $119.6K | 0.0% | Index | Very Low | Phoenix, AZ | 2026-11-03 | |
| 11,930 | $89.5K | 0.0% | Growth | Medium | Shanghai, France | 2026-10-28 | |
| 10,071 | $75.6K | 0.0% | Core | Low | Plymouth, MN | 2026-10-13 | |
| 5,866 | $45.4K | 0.0% | GARP | Low | Mansfield, OH | 2026-10-27 | |
| 3,568 | $27.6K | 0.0% | Index | Very Low | St. Louis, MO | 2026-10-20 | |
| 3,534 | $27.3K | 0.0% | Core | Very High | Chicago, IL | 2026-11-04 | |
| 3,341 | $25.8K | 0.0% | Growth | Low | Seoul, Malaysia | 2026-11-03 | |
| 1,756 | $13.6K | 0.0% | Core | Medium | Birmingham, AL | 2026-11-04 | |
| 1,555 | $12.0K | 0.0% | Value | Medium | Rancho Santa Fe, CA | 2026-10-14 | |
| 1,476 | $11.4K | 0.0% | Agg Growth | Medium | Guangzhou, France | 2026-10-26 | |
| 1,225 | $9.5K | 0.0% | GARP | Medium | Charlotte, NC | 2026-10-22 | |
| 1,000 | $7.7K | 0.0% | Core | Low | Newport News, VA | 2026-10-28 | |
| 925 | $7.2K | 0.0% | GARP | Low | Phoenix, AZ | 2026-10-02 | |
| 757 | $5.9K | 0.0% | Index | Low | Minneapolis, MN | 2026-11-05 | |
| 731 | $5.7K | 0.0% | Index | Very Low | Foster City, CA | 2026-10-08 | |
| 707 | $5.5K | 0.0% | ETF | Very Low | Sylvania, OH | 2026-10-26 | |
| 515 | $4.0K | 0.0% | Growth | Low | Tampa, FL | 2026-10-16 | |
| 510 | $3.9K | 0.0% | Index | Low | Greenwood Village, CO | 2026-10-20 | |
| 369 | $2.9K | 0.0% | Core | Low | Springfield, MA | 2026-10-05 | |
| 263 | $2.0K | 0.0% | Index | Low | San Francisco, CA | 2026-10-08 | |
| 163 | $1.3K | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-10-22 | |
| 157 | $1.2K | 0.0% | Index | Low | San Francisco, CA | 2026-11-03 | |
| 139 | $1.1K | 0.0% | ETF | Medium | Encinitas, CA | 2026-10-21 | |
| 110 | $0 | 0.0% | Growth | Very High | New York, NY | 2026-10-16 | |
| 97 | $751 | 0.0% | ETF | Low | Princeton, NJ | 2026-10-19 | |
| 94 | $728 | 0.0% | ETF | Medium | Akron, OH | 2026-10-13 | |
| 75 | $581 | 0.0% | Core | Very Low | Saint Louis, MO | 2026-10-27 | |
| 71 | $549 | 0.0% | Index | Low | Atlanta, GA | 2026-10-23 | |
| 71 | $549 | 0.0% | Index | Very Low | Cincinnati, OH | 2026-11-05 | |
| 49 | $379 | 0.0% | Core | Low | Baltimore, MD | 2026-10-27 | |
| 35 | $271 | 0.0% | ETF | Medium | Melbourne, FL | 2026-11-05 | |
| 34 | $0 | 0.0% | Value | High | London, United Kingdom | 2026-10-30 | |
| 28 | $0 | 0.0% | ETF | Low | Shaker Heights, OH | 2026-10-27 | |
| 2 | $15 | 0.0% | Core | High | Zurich, Switzerland | 2026-10-29 |