CUSIP: 152309100 | US | Healthcare · Biotechnology | Mid Cap | 295 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13G/AFMR LLC | 1,800 | 0.0% | Newly reported | Jun 30, 2026 | 91d ahead of 13F (6,852,047 sh) · −6,850,247 |
| 13G/AMedicxi Secondary I GP Limited | 0 | 0.0% | No shares held | Jun 30, 2026 | No 13F filer matched |
| 13G/AIndex Ventures Life VI (Jersey) L.P. | 0 | 0.0% | No shares held | Jun 30, 2026 | No 13F filer matched |
| 13G/APentwater Capital Management LP | 0 | 0.0% | No shares held | Jun 30, 2026 | No 13F filer matched |
| 13G/AAdage Capital Management, L.P. | 0 | 0.0% | No shares held | Jun 30, 2026 | No 13F filer matched |
| 13D/AFarallon Capital Management, L.L.C. | 0 | 0.0% | Fell below 5% | Jun 24, 2026 | 85d ahead of 13F (4,809,000 sh) · −4,809,000 |
| 13D/AGeneral Atlantic Cooperatief U.A. | 7,366,818 | 5.0% | −2,315,000 | Nov 25, 2025 | No 13F filer matched |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 19,963,157 | $792.9M | 80.8% | GARP | Very Low | St. Helier, Venezuela | 2026-04-21 | |
| 11,430,455 | $454.0M | 4.5% | Agg Growth | Medium | New York, NY | 2026-05-15 | |
| 9,961,789 | $395.7M | 100.0% | N/A | N/A | St. Helier, Venezuela | 2026-05-15 | |
| 8,925,010 | $354.5M | 0.5% | Core | Medium | Boston, MA | 2026-05-15 | |
| 8,170,000 | $324.5M | 1.7% | Value | Very High | Naples, FL | 2026-05-15 | |
| 6,852,047 | $272.2M | 0.0% | Growth | Medium | Boston, MA | 2026-05-15 | |
| 6,000,000 | $238.3M | 10.1% | Deep Value | Medium | San Francisco, CA | 2026-05-15 | |
| 5,258,903 | $208.9M | 4.1% | Core | High | New York, NY | 2026-05-29 | |
| 4,832,548 | $191.9M | 0.0% | Core | Medium | Los Angeles, CA | 2026-05-13 | |
| 4,809,000 | $191.0M | 1.0% | Growth | Medium | San Francisco, CA | 2026-08-14 | |
| 4,286,480 | $170.3M | 4.9% | Growth | Medium | Palo Alto, CA | 2026-05-15 | |
| 4,268,353 | $169.5M | 0.0% | Core | Low | New York, NY | 2026-05-15 | |
| 3,574,048 | $142.0M | 2.9% | Agg Growth | High | New York, NY | 2026-05-15 | |
| 3,492,977 | $138.7M | 0.1% | N/A | N/A | London, United Kingdom | 2026-05-18 | |
| 3,158,041 | $125.4M | 2.0% | Core | High | Greenwich, CT | 2026-05-15 | |
| 2,125,000 | $84.4M | 4.2% | Value | Very High | San Francisco, CA | 2026-05-15 | |
| 2,054,175 | $81.6M | 0.8% | Agg Growth | Medium | New York, NY | 2026-05-15 | |
| 2,049,439 | $81.4M | 0.1% | Core | Medium | Pittsburgh, PA | 2026-05-11 | |
| 1,986,768 | $78.9M | 2.6% | Core | High | Stamford, CT | 2026-05-15 | |
| 1,932,406 | $76.8M | 0.0% | Core | Low | Charlotte, NC | 2026-05-18 | |
| 1,854,488 | $73.7M | 0.8% | Growth | High | Dallas, TX | 2026-05-15 | |
| 1,560,991 | $62.0M | 5.6% | Core | High | Edina, MN | 2026-05-15 | |
| 1,400,000 | $55.6M | 2.9% | Deep Value | High | New York, NY | 2026-05-14 | |
| 1,364,019 | $54.2M | 11.8% | Deep Value | Medium | West Hollywood, CA | 2026-05-15 | |
| 1,354,830 | $53.8M | 2.5% | GARP | Low | New York, NY | 2026-05-15 | |
| 1,144,560 | $45.5M | 0.0% | Core | Medium | New York, NY | 2026-05-15 | |
| 1,053,464 | $41.8M | 1.2% | Growth | Medium | New York, NY | 2026-05-14 | |
| 1,050,000 | $41.7M | 2.1% | Core | Medium | Boston, MA | 2026-05-15 | |
| 865,500 | $34.4M | 2.0% | Deep Value | Very High | Palm Beach, FL | 2026-04-21 | |
| 859,105 | $34.1M | 0.1% | Core | High | San Francisco, CA | 2026-05-15 | |
| 852,828 | $33.9M | 0.0% | Core | Very High | Chicago, IL | 2026-05-15 | |
| 750,000 | $29.8M | 3.3% | Growth | High | New York, NY | 2026-05-15 | |
| 722,121 | $28.7M | 0.0% | Core | Very High | New York, NY | 2026-05-15 | |
| 702,254 | $27.9M | 0.0% | Growth | Medium | Paris, India | 2026-05-14 | |
| 687,427 | $27.3M | 0.0% | GARP | Medium | Kansas City, MO | 2026-05-15 | |
| 684,482 | $27.2M | 0.0% | Core | Medium | San Mateo, CA | 2026-05-13 | |
| 670,751 | $26.6M | 0.2% | Agg Growth | Very Low | New York, NY | 2026-05-15 | |
| 668,142 | $26.5M | 0.4% | Growth | Medium | Boston, MA | 2026-05-15 | |
| 654,850 | $26.0M | 0.0% | Core | Medium | Toronto, Ontario, Australia | 2026-05-15 | |
| 648,326 | $25.8M | 1.2% | Deep Value | Very High | New York, NY | 2026-05-15 | |
| 643,808 | $25.6M | 0.0% | GARP | High | New York, NY | 2026-05-15 | |
| 635,000 | $25.2M | 2.3% | GARP | Medium | Boston, MA | 2026-05-15 | |
| 628,049 | $24.9M | 0.0% | Value | Very High | London, United Kingdom | 2026-05-15 | |
| 625,420 | $24.8M | 0.0% | Index | Very Low | New York, NY | 2026-05-13 | |
| 598,197 | $23.8M | 0.0% | Core | Very High | Miami, FL | 2026-05-15 | |
| 580,945 | $23.1M | 6.4% | Deep Value | Low | San Francisco, CA | 2026-05-15 | |
| 528,224 | $21.0M | 1.9% | Core | High | San Francisco, CA | 2026-05-15 | |
| 510,407 | $20.3M | 0.3% | Growth | Very High | Boston, MA | 2026-08-14 | |
| 489,849 | $19.5M | 4.7% | Deep Value | High | New York, NY | 2026-05-14 | |
| 477,597 | $13.2M | 0.0% | Growth | Medium | New York, NY | 2026-05-13 | |
| 466,345 | $18.5M | 1.9% | Growth | High | Boston, MA | 2026-05-14 | |
| 390,951 | $15.5M | 0.1% | Value | Very High | Stamford, CT | 2026-05-15 | |
| 359,939 | $14.3M | 0.0% | Core | Medium | Zurich, Switzerland | 2026-05-05 | |
| 351,828 | $14.0M | 0.8% | Agg Growth | Medium | Baltimore, MD | 2026-05-15 | |
| 325,001 | $12.9K | 0.0% | Deep Value | Very High | New York, NY | 2026-05-14 | |
| 320,430 | $12.7M | 0.0% | Core | Very High | Chicago, IL | 2026-05-15 | |
| 307,355 | $12.2M | 0.0% | Core | Very High | Stamford, CT | 2026-05-15 | |
| 278,064 | $11.0M | 0.1% | Value | Medium | New York, NY | 2026-05-12 | |
| 274,116 | $10.9M | 0.1% | Core | Very High | Oklahoma City, OK | 2026-05-15 | |
| 254,803 | $10.1M | 0.4% | Yield | Medium | New Canaan, CT | 2026-05-15 | |
| 242,044 | $9.6M | 0.0% | Core | Low | Toronto, Australia | 2026-05-11 | |
| 236,785 | $9.4M | 3.8% | ETF | Low | St. Paul, MN | 2026-05-06 | |
| 214,291 | $8.5M | 1.5% | Agg Growth | High | Greenwich, CT | 2026-05-15 | |
| 206,847 | $8.2M | 0.3% | Value | Very High | Fort Worth, TX | 2026-05-15 | |
| 189,961 | $7.5M | 0.0% | Core | Medium | Frankfurt Am Main, Hong Kong | 2026-05-06 | |
| 185,000 | $7.3M | 0.0% | Core | High | New York, NY | 2026-05-14 | |
| 171,933 | $6.8M | 0.0% | GARP | Very High | New York, NY | 2026-05-15 | |
| 170,016 | $6.8K | 0.0% | Core | High | Baltimore, MD | 2026-05-15 | |
| 168,177 | $6.7M | 0.0% | GARP | High | London, United Kingdom | 2026-05-15 | |
| 168,170 | $6.7M | 0.0% | Agg Growth | Medium | New York, NY | 2026-05-15 | |
| 160,942 | $6.4M | 0.0% | Core | Very High | New York, NY | 2026-05-15 | |
| 158,509 | $6.3M | 0.5% | Value | Very High | Austin, TX | 2026-05-15 | |
| 150,000 | $6.0M | 0.3% | Agg Growth | Very High | New York, NY | 2026-05-15 | |
| 137,741 | $5.5M | 1.4% | GARP | Medium | Sydney Australia 2000, China | 2026-05-14 | |
| 125,000 | $5.0M | 0.0% | GARP | Very High | London, United Kingdom | 2026-05-15 | |
| 116,992 | $4.6K | 0.0% | GARP | Very High | New York, NY | 2026-05-14 | |
| 111,956 | $4.4M | 0.0% | Value | Very High | Jupiter, FL | 2026-05-15 | |
| 110,207 | $4.3M | 0.0% | Index | Very Low | London, United Kingdom | 2026-05-08 | |
| 109,327 | $4.3M | 0.0% | Value | Very High | San Francisco, CA | 2026-05-15 | |
| 107,778 | $4.3M | 0.0% | Index | Very Low | Boston, MA | 2026-05-15 | |
| 98,028 | $3.9M | 0.1% | Deep Value | Very High | Greenwich, CT | 2026-05-15 | |
| 96,910 | $2.7M | 0.0% | Growth | Medium | Carouge, Switzerland | 2026-04-22 | |
| 96,367 | $3.8M | 0.1% | Value | Very High | Hong Kong, South Korea | 2026-04-27 | |
| 93,685 | $3.7M | 0.7% | Growth | Very High | Hong Kong, South Korea | 2026-05-11 | |
| 80,000 | $3.2M | 1.5% | Value | Very High | New York, NY | 2026-05-15 | |
| 74,276 | $3.0M | 0.0% | Core | Medium | New York, NY | 2026-05-11 | |
| 71,513 | $2.8M | 0.0% | GARP | Very High | New York, NY | 2026-05-15 | |
| 67,775 | $2.7K | 0.0% | GARP | Very High | New York, NY | 2026-05-14 | |
| 59,844 | $2.4M | 0.0% | Value | High | New York, NY | 2026-05-15 | |
| 50,606 | $2.0M | 0.0% | GARP | Very High | New York, NY | 2026-05-15 | |
| 41,000 | $1.6M | 0.2% | Deep Value | Very High | New York, NY | 2026-05-15 | |
| 40,968 | $1.6M | 0.0% | Core | Very High | New York, NY | 2026-05-12 | |
| 39,656 | $1.6M | 0.0% | Value | Very High | New York, NY | 2026-05-15 | |
| 39,000 | $1.5M | 0.9% | Growth | Medium | Syosset, NY | 2026-05-14 | |
| 38,812 | $1.5M | 0.0% | Core | Low | Seattle, WA | 2026-05-08 | |
| 38,566 | $1.5M | 0.1% | Value | High | Austin, TX | 2026-05-18 | |
| 36,254 | $1.4M | 0.0% | Growth | Medium | Strassen, Netherlands | 2026-04-30 | |
| 30,000 | $1.2M | 0.7% | Core | Low | Harrison, NY | 2026-05-15 | |
| 29,670 | $1.2M | 0.0% | Growth | Medium | Atlanta, GA | 2026-05-12 | |
| 25,350 | $1.0M | 0.1% | Value | Very High | New York, NY | 2026-05-15 | |
| 24,174 | $960.2K | 0.0% | Core | High | Berkeley, CA | 2026-05-15 | |
| 24,000 | $953.3K | 0.3% | Yield | Very High | Westport, CT | 2026-05-14 | |
| 21,225 | $843.1K | 0.1% | Growth | Medium | Shanghai, France | 2026-04-28 | |
| 20,887 | $829.6K | 0.1% | Value | Low | Aspen, CO | 2026-05-08 | |
| 20,000 | $794.4K | 0.2% | Deep Value | Medium | New York, NY | 2026-05-15 | |
| 20,000 | $794.4K | 0.1% | Growth | High | Cohasset, MA | 2026-08-17 | |
| 19,436 | $772.0K | 0.0% | GARP | Medium | Houston, TX | 2026-05-11 | |
| 18,113 | $719.4K | 0.1% | Deep Value | Very High | Dallas, TX | 2026-05-15 | |
| 18,101 | $719.0K | 0.1% | ETF | Low | Exton, PA | 2026-05-14 | |
| 17,737 | $704.5K | 0.0% | Growth | High | Bala Cynwyd, PA | 2026-05-15 | |
| 17,600 | $699.1K | 0.0% | Value | Low | Rye, NY | 2026-05-14 | |
| 17,000 | $675.2K | 0.0% | Deep Value | High | Chicago, IL | 2026-05-15 | |
| 16,893 | $671.0K | 0.0% | Core | Medium | Minneapolis, MN | 2026-07-17 | |
| 16,893 | $671.0K | 0.0% | Core | Medium | Minneapolis, MN | 2026-07-17 | |
| 15,595 | $621.9K | 0.0% | Core | Low | Toronto, Australia | 2026-05-12 | |
| 15,000 | $595.8K | 0.1% | Yield | Very High | New York, NY | 2026-05-15 | |
| 14,913 | $411.3K | 0.1% | Value | Very High | Greenwich, CT | 2026-05-12 | |
| 13,965 | $554.7K | 0.0% | GARP | Medium | Toronto, Australia | 2026-05-15 | |
| 13,102 | $520.4K | 0.0% | Core | Low | Westport, CT | 2026-05-14 | |
| 12,699 | $504.4K | 0.0% | Value | Very High | Chicago, IL | 2026-05-15 | |
| 12,332 | $489.8K | 0.0% | Core | Medium | Charlotte, NC | 2026-05-05 | |
| 10,394 | $412.9K | 0.0% | Core | Medium | Oslo, Norway | 2026-05-14 | |
| 10,286 | $408.6K | 0.1% | Core | High | Hartford, CT | 2026-05-14 | |
| 9,400 | $373.4K | 0.1% | Momentum | Very High | Rye, NY | 2026-05-14 | |
| 9,030 | $358.7K | 0.0% | Core | High | Zurich, Switzerland | 2026-05-15 | |
| 9,000 | $357.5K | 0.3% | Yield | Very High | New Canaan, CT | 2026-05-15 | |
| 8,303 | $329.8K | 0.0% | Value | Very High | Jersey City, NJ | 2026-05-13 | |
| 8,298 | $329.6K | 0.0% | Core | Low | New York, NY | 2026-05-05 | |
| 7,443 | $295.6K | 0.0% | N/A | N/A | Riverhead, NY | 2026-04-29 | |
| 7,034 | $279.4K | 0.0% | Growth | Low | Atlanta, GA | 2026-07-15 | |
| 6,991 | $277.7K | 0.0% | Value | Very High | Chicago, IL | 2026-05-13 | |
| 6,975 | $277.0K | 0.0% | ETF | Low | Berwyn, PA | 2026-05-04 | |
| 6,922 | $274.9K | 0.0% | Core | Medium | London, United Kingdom | 2026-05-15 | |
| 6,900 | $274.1K | 0.0% | Core | Medium | Munich, Hong Kong | 2026-05-11 | |
| 6,551 | $260.2K | 0.0% | ETF | Low | New York, NY | 2026-05-12 | |
| 6,238 | $247.8K | 0.0% | Growth | Low | Seoul, Malaysia | 2026-08-12 | |
| 6,000 | $238.3K | 0.0% | Core | Low | San Francisco, CA | 2026-07-08 | |
| 6,000 | $238.3K | 0.0% | ETF | Medium | Morristown, NJ | 2026-04-27 | |
| 5,964 | $236.9K | 0.1% | Growth | High | Boston, MA | 2026-05-15 | |
| 5,351 | $212.5K | 0.0% | Growth | Low | Bethesda, MD | 2026-04-27 | |
| 5,083 | $201.9K | 0.1% | Core | Medium | Wellesley, MA | 2026-05-11 | |
| 3,980 | $158.1K | 0.0% | Index | Very Low | Foster City, CA | 2026-04-06 | |
| 3,081 | $122 | 0.0% | Growth | High | New York, NY | 2026-04-16 | |
| 2,482 | $98.6K | 0.0% | Core | Medium | Paris, India | 2026-05-12 | |
| 2,166 | $86.0K | 0.0% | Agg Growth | Medium | Guangzhou, France | 2026-04-15 | |
| 1,947 | $77.3K | 0.1% | Deep Value | Very High | London, United Kingdom | 2026-04-15 | |
| 1,164 | $46.0K | 0.0% | Core | Low | Toronto, Australia | 2026-05-15 | |
| 925 | $36.7K | 0.0% | Growth | Low | Saratoga Springs, NY | 2026-04-03 | |
| 397 | $15.8K | 0.0% | ETF | Low | New York, NY | 2026-05-04 | |
| 277 | $8.0K | 0.0% | Index | Low | Des Peres, MO | 2026-05-15 | |
| 128 | $5.1K | 0.0% | Index | Very Low | Bellevue, WA | 2026-06-24 | |
| 81 | $3.2K | 0.0% | Core | Low | Stamford, CT | 2026-05-08 | |
| 60 | $2.4K | 0.0% | Core | Medium | Birmingham, AL | 2026-04-14 | |
| 41 | $1.6K | 0.0% | GARP | Very High | New York, NY | 2026-05-15 | |
| 30 | $1.2K | 0.0% | ETF | Medium | Fairfax, VA | 2026-04-02 | |
| 30 | $1.2K | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-04-28 | |
| 25 | $993 | 0.0% | Core | Medium | Montreal, Austria | 2026-05-15 | |
| 22 | $874 | 0.0% | ETF | Very Low | Sylvania, OH | 2026-04-23 | |
| 20 | $797 | 0.0% | Index | Low | San Francisco, CA | 2026-04-07 | |
| 15 | $596 | 0.0% | Index | Low | San Francisco, CA | 2026-06-03 | |
| 12 | $477 | 0.0% | Core | Medium | Birmingham, AL | 2026-05-18 | |
| 1 | $40 | 0.0% | Core | Low | Zurich, Switzerland | 2026-05-15 |