CUSIP: 4525EP101 | NYSE | Healthcare · Biotechnology | Micro Cap | 241 institutional holders
5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.
| Holder | Shares | % of Class | Change | Event Date | vs 13F |
|---|---|---|---|---|---|
| 13GOrbiMed Advisors LLC with OrbiMed Capital LLC | 756,860 | 5.3% | New 5%+ stake | Jun 30, 2026 | No 13F filer matched |
| Style | Turnover | Location | Filed | ||||
|---|---|---|---|---|---|---|---|
| 8,243,941 | $9.2M | 0.0% | Core | Low | Edinburgh, United Kingdom | 2026-04-29 | |
| 7,652,972 | $8.5M | 0.3% | Core | Medium | San Francisco, CA | 2026-05-15 | |
| 6,699,411 | $7.4M | 1.5% | Agg Growth | High | Dallas, TX | 2026-05-28 | |
| 5,138,316 | $5.7M | 0.0% | Core | N/A | Malvern, PA | 2026-05-15 | |
| 4,500,000 | $5.0M | 0.2% | Core | Very High | Greenwich, CT | 2026-05-14 | |
| 3,882,162 | $4.3M | 0.2% | Growth | Very High | New York, NY | 2026-05-14 | |
| 3,779,922 | $4.2M | 0.0% | Core | Very High | New York, NY | 2026-05-15 | |
| 3,288,540 | $3.7M | 0.0% | Core | Low | New York, NY | 2026-05-15 | |
| 2,506,491 | $2.8M | 0.1% | Yield | Medium | New Canaan, CT | 2026-05-15 | |
| 2,450,000 | $2.7M | 0.1% | Deep Value | High | New York, NY | 2026-05-15 | |
| 2,344,779 | $2.6M | 1.7% | Value | High | Los Angeles, CA | 2026-05-14 | |
| 1,525,769 | $1.7M | 0.0% | Index | Very Low | Boston, MA | 2026-05-15 | |
| 1,398,600 | $1.6M | 0.0% | Core | Medium | Boston, MA | 2026-05-15 | |
| 1,028,256 | $1.1M | 0.0% | Growth | High | Bala Cynwyd, PA | 2026-05-15 | |
| 967,152 | $1.1M | 0.0% | Core | High | San Francisco, CA | 2026-05-15 | |
| 964,230 | $1.1M | 0.0% | Index | Very Low | New York, NY | 2026-05-13 | |
| 919,164 | $1.0M | 0.0% | Core | High | New York, NY | 2026-05-14 | |
| 674,662 | $748.9K | 0.1% | Deep Value | Very High | Dallas, TX | 2026-05-15 | |
| 659,153 | $731.7K | 0.0% | Core | Very High | New York, NY | 2026-05-12 | |
| 565,645 | $627.9K | 0.0% | Index | Very Low | Boston, MA | 2026-05-15 | |
| 522,797 | $580.3K | 0.0% | Core | Medium | Zurich, Switzerland | 2026-05-05 | |
| 493,393 | $547 | 0.0% | GARP | Very High | New York, NY | 2026-05-14 | |
| 438,932 | $487.2K | 0.0% | Core | Low | Las Vegas, NV | 2026-04-27 | |
| 263,328 | $292.3K | 0.0% | Index | Very Low | Chicago, IL | 2026-05-14 | |
| 213,017 | $236.4K | 0.0% | Growth | Very High | Stamford, CT | 2026-05-13 | |
| 169,300 | $187.9K | 0.0% | Index | Very Low | Fort Mill, SC | 2026-05-06 | |
| 168,300 | $186.8K | 0.0% | Core | High | Toronto, Australia | 2026-05-15 | |
| 149,770 | $166.2K | 0.0% | Core | Medium | New York, NY | 2026-05-15 | |
| 143,867 | $159.7K | 0.0% | Core | Low | Charlotte, NC | 2026-05-18 | |
| 121,850 | $135.3K | 0.0% | Core | Medium | Paris, India | 2026-05-12 | |
| 114,487 | $127.1K | 0.0% | Core | Very High | Miami, FL | 2026-05-15 | |
| 113,366 | $126 | 0.0% | GARP | Very High | New York, NY | 2026-05-14 | |
| 111,460 | $123.7K | 0.0% | Value | Very High | London, United Kingdom | 2026-05-15 | |
| 100,000 | $111.0K | 0.0% | ETF | Low | Grand Rapids, MI | 2026-05-15 | |
| 91,450 | $101.5K | 0.0% | Index | Very Low | Atlanta, GA | 2026-04-27 | |
| 90,630 | $100.6K | 0.0% | Index | Low | Springfield, MA | 2026-05-04 | |
| 85,000 | $94.4K | 0.0% | Index | Very Low | San Francisco, CA | 2026-05-15 | |
| 67,186 | $74.6K | 0.0% | Value | High | New York, NY | 2026-05-15 | |
| 48,500 | $54 | 0.0% | ETF | Low | Fairfield, IA | 2026-04-30 | |
| 45,843 | $50.9K | 0.0% | Core | Very High | St. Helier, Venezuela | 2026-05-15 | |
| 35,022 | $38.9K | 0.0% | Index | Very Low | Overland Park, KS | 2026-05-12 | |
| 33,297 | $37.0K | 0.0% | Value | Very High | Rowayton, CT | 2026-05-15 | |
| 32,868 | $36.5K | 0.0% | GARP | Very High | New York, NY | 2026-05-15 | |
| 30,824 | $34.2K | 0.0% | Value | Very High | London, United Kingdom | 2026-05-15 | |
| 30,000 | $0 | 0.0% | Value | High | Austin, TX | 2026-05-18 | |
| 29,627 | $32.9K | 0.0% | GARP | Very High | London, United Kingdom | 2026-05-15 | |
| 28,358 | $31.5K | 0.0% | Core | Low | New York, NY | 2026-05-05 | |
| 28,300 | $31.4K | 0.0% | GARP | Very High | New York, NY | 2026-05-15 | |
| 26,635 | $29.6K | 0.0% | Growth | Very High | Jersey City, NJ | 2026-05-15 | |
| 24,390 | $27.1K | 0.1% | Growth | Very High | Chicago, IL | 2026-05-21 | |
| 22,100 | $24.5K | 0.0% | Growth | Very Low | Miami, FL | 2026-05-15 | |
| 20,400 | $22.6K | 0.0% | ETF | Medium | East Greenwich, RI | 2026-04-16 | |
| 20,000 | $22.2K | 0.0% | Index | Low | Scottsdale, AZ | 2026-05-15 | |
| 18,151 | $20.1K | 0.0% | Value | Very High | Jersey City, NJ | 2026-05-13 | |
| 12,000 | $13.3K | 0.0% | Agg Growth | Medium | Scottsdale, AZ | 2026-04-16 | |
| 11,281 | $8.2K | 0.0% | Core | High | Unterschleissheim, Hong Kong | 2026-05-08 | |
| 10,360 | $11.5K | 0.0% | ETF | Low | Waltham, MA | 2026-04-27 | |
| 10,000 | $11.1K | 0.0% | ETF | Medium | Morristown, NJ | 2026-04-27 | |
| 10,000 | $11.1K | 0.0% | ETF | Low | Phoenix, AZ | 2026-04-08 | |
| 10,000 | $11.1K | 0.0% | ETF | Low | Lake Forest, IL | 2026-05-06 | |
| 8,642 | $9.6K | 0.0% | Growth | Very Low | Omaha, NE | 2026-05-14 | |
| 3,765 | $4.2K | 0.0% | Agg Growth | Low | Tokyo, Mexico | 2026-04-28 | |
| 3,005 | $3.0K | 0.0% | Core | Low | Toronto, Australia | 2026-05-15 | |
| 2,428 | $2.7K | 0.0% | Core | Medium | London, United Kingdom | 2026-05-15 | |
| 1,702 | $1.9K | 0.0% | Value | Very High | Chicago, IL | 2026-05-13 | |
| 1,505 | $1.7K | 0.0% | Index | Very Low | Milwaukee, WI | 2026-05-07 | |
| 1,000 | $1.1K | 0.0% | Core | Low | New York, NY | 2026-05-14 | |
| 900 | $999 | 0.0% | Core | Low | San Francisco, CA | 2026-07-08 | |
| 455 | $505 | 0.0% | Growth | Medium | Boston, MA | 2026-05-15 | |
| 407 | $419 | 0.0% | Growth | Medium | New York, NY | 2026-05-13 | |
| 140 | $155 | 0.0% | ETF | Medium | Plymouth, MA | 2026-05-08 | |
| 21 | $22 | 0.0% | Index | Very Low | Boston, MA | 2026-05-15 | |
| 3 | $3 | 0.0% | Growth | Very High | Hong Kong, South Korea | 2026-05-11 | |
| 0 | $0 | 0.0% | N/A | N/A | Valley Forge, PA | 2026-05-14 |