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Septerna Inc (SEPN)

CUSIP: 81734D104 | NYSE | Healthcare · Biotechnology | Small Cap | 221 institutional holders

Quarters

Q3 2026Q2 2026Q1 2026Q4 2025Q3 2025
CompareDetailedHistoricalFundsOptions13D/13GPeersTargetingTrading SummaryProfile

Beneficial Ownership — 13D / 13G

Full history →

5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.

HolderShares% of ClassChangeEvent Datevs 13F
13D/ARA Capital Management, L.P.
with RA Capital Healthcare Fund, L.P.
5,525,32411.8%New 5%+ stakeAug 12, 20266,995,858 sh (Jun 30, 2026)
13D/A

Institutional Holders — Q3 2026

Dimensional Fund Advisors LP107,373
0.0% of portfolio›$4.2M
Hussman Strategic Advisors, Inc.63,000
0.5% of portfolio›$2.5M
Bank of New York Mellon Corp58,022
0.0% of portfolio›$2.3M
Profund Advisors LLC38,262
0.0% of portfolio›$1.5M
Strs Ohio27,200
0.0% of portfolio›$1.1M
Virginia Retirement Systems ET Al16,600
0.0% of portfolio›$649.6K
Citigroup Inc13,530
0.0% of portfolio›$529.4K
China Universal Asset Management Co., Ltd.12,117
0.0% of portfolio›$474.1K
Creative Planning7,772
0.0% of portfolio›$304.1K
Prospera Financial Services Inc6,171
0.0% of portfolio›$271.5K
State of New Jersey Common Pension Fund D5,459
0.0% of portfolio›$213.6K
Chung Wu Investment Group, LLC4,500
0.1% of portfolio›$176.1K
State of Wyoming4,328
0.0% of portfolio›$169.4K
Covestor Ltd2,526
0.0% of portfolio›$98
Mirae Asset Global Investments Co., Ltd.2,385
0.0% of portfolio›$93.3K
New York State Teachers Retirement System1,946
0.0% of portfolio›$76
Gamma Investing LLC1,378
0.0% of portfolio›$53.9K
GF Fund Management Co. Ltd.1,033
0.0% of portfolio›$40.4K
Nisa Investment Advisors, LLC829
0.0% of portfolio›$32.4K
Sterling Capital Management LLC630
0.0% of portfolio›$24.7K
Pinnacle Wealth Planning Services, Inc.322
0.0% of portfolio›$12.6K
Versant Capital Management, Inc261
0.0% of portfolio›$10.2K
US Bancorp \de\230
0.0% of portfolio›$9.0K
Larson Financial Group LLC205
0.0% of portfolio›$8.0K
Signaturefd, LLC141
0.0% of portfolio›$5.5K
MassMutual Private Wealth & Trust, FSB104
0.0% of portfolio›$4.1K
EverSource Wealth Advisors, LLC64
0.0% of portfolio›$2.5K
SBI Securities Co., Ltd.55
0.0% of portfolio›$2.2K
Financial Consulate, Inc22
0.0% of portfolio›$861
Fortitude Family Office, LLC20
0.0% of portfolio›$783
Parkside Financial Bank & Trust10
0.0% of portfolio›$391
SJS Investment Consulting Inc.8
0.0% of portfolio›$314
Silver Grove Financial Group, Inc.5
0.0% of portfolio›$196
Root Financial Partners, LLC3
0.0% of portfolio›$117
Farther Finance Advisors, LLC2
0.0% of portfolio›$78
StyleTurnoverLocationFiled
Dimensional Fund Advisors LP
107,373$4.2M0.0%IndexLowAustin, TX2026-11-04
Hussman Strategic Advisors, Inc.
63,000$2.5M0.5%YieldVery HighEllicott City, MD2026-11-02
Bank of New York Mellon Corp
58,022$2.3M0.0%CoreLowNew York, NY2026-11-05
Profund Advisors LLC
38,262$1.5M0.0%GrowthLowBethesda, MD2026-10-29
Strs Ohio
27,200$1.1M0.0%CoreMediumColumbus, OH2026-10-30
Virginia Retirement Systems ET Al
16,600$649.6K0.0%CoreMediumRichmond, VA2026-10-28
Citigroup Inc
13,530$529.4K0.0%CoreMediumNew York, NY2026-11-04
China Universal Asset Management Co., Ltd.
12,117$474.1K0.0%GrowthMediumShanghai, France2026-10-28
Creative Planning
7,772$304.1K0.0%IndexVery LowOverland Park, KS2026-11-02
Prospera Financial Services Inc
6,171$271.5K0.0%CoreMediumDallas, TX2026-11-04
State of New Jersey Common Pension Fund D
5,459$213.6K0.0%CoreLowTrenton, NJ2026-11-05
Chung Wu Investment Group, LLC
4,500$176.1K0.1%GrowthMediumSugar Land, TX2026-11-03
State of Wyoming
4,328$169.4K0.0%ValueHighCheyenne, WY2026-10-28
Covestor Ltd
2,526$980.0%ValueHighLondon, United Kingdom2026-10-30
Mirae Asset Global Investments Co., Ltd.
2,385$93.3K0.0%GrowthLowSeoul, Malaysia2026-11-03
New York State Teachers Retirement System
1,946$760.0%CoreVery LowAlbany, NY2026-10-22
Gamma Investing LLC
1,378$53.9K0.0%IndexVery LowFoster City, CA2026-10-08
GF Fund Management Co. Ltd.
1,033$40.4K0.0%Agg GrowthMediumGuangzhou, France2026-10-26
Nisa Investment Advisors, LLC
829$32.4K0.0%IndexVery LowSt. Louis, MO2026-10-20
Sterling Capital Management LLC
630$24.7K0.0%GARPMediumCharlotte, NC2026-10-22
Pinnacle Wealth Planning Services, Inc.
322$12.6K0.0%GARPLowMansfield, OH2026-10-27
Versant Capital Management, Inc
261$10.2K0.0%GARPLowPhoenix, AZ2026-10-02
US Bancorp \de\
230$9.0K0.0%IndexLowMinneapolis, MN2026-11-05
Larson Financial Group LLC
205$8.0K0.0%GrowthLowSt Louis, MO2026-11-05
Signaturefd, LLC
141$5.5K0.0%IndexLowAtlanta, GA2026-10-23
MassMutual Private Wealth & Trust, FSB
104$4.1K0.0%CoreLowSpringfield, MA2026-10-05
EverSource Wealth Advisors, LLC
64$2.5K0.0%CoreMediumBirmingham, AL2026-11-04
SBI Securities Co., Ltd.
55$2.2K0.0%Agg GrowthLowTokyo, Mexico2026-10-22
Financial Consulate, Inc
22$8610.0%ETFLowHunt Valley, MD2026-10-23
Fortitude Family Office, LLC
20$7830.0%ETFMediumScottsdale, AZ2026-10-14
Parkside Financial Bank & Trust
10$3910.0%CoreVery LowSaint Louis, MO2026-10-27
SJS Investment Consulting Inc.
8$3140.0%ETFVery LowSylvania, OH2026-10-26
Silver Grove Financial Group, Inc.
5$1960.0%CoreMediumOrchard Park, NY2026-11-05
Root Financial Partners, LLC
3$1170.0%ETFMediumEncinitas, CA2026-10-21
Farther Finance Advisors, LLC
2$780.0%IndexLowSan Francisco, CA2026-10-08
RA Capital Management, L.P.
5,525,324
11.8% of class · Aug 12, 2026New 5%+ stake
with RA Capital Healthcare Fund, L.P.
6,995,858 sh (Jun 30, 2026)