Wave Life Sciences Inc (WVE)

CUSIP: 94352A104 | NYSE | Healthcare · Biotechnology | Small Cap | 93 institutional holders

Compare Detailed Historical Funds Options Short Interest 13D/13G Peers Targeting Trading Summary Profile

Beneficial Ownership — 13D / 13G

5%+ stakes reported outside the quarterly cycle. A 13D is due within five business days of the event below, so these figures lead the holders table until the filer's next 13F catches up to them.

Holder	Shares	% of Class	Change	Event Date	vs 13F
13D/A RA Capital Management, L.P. with RA Capital Healthcare Fund, L.P.	34,314,406	16.8%	New 5%+ stake	Aug 7, 2026	Not yet in a 13F
13G BlackRock, Inc.

Institutional Holders — Q3 2026

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GSK plc18,245,691

13.6% of portfolio$67.5M

FMR LLC3,835,270

0.0% of portfolio$14.2M

Geode Capital Management, LLC3,517,585

0.0% of portfolio$13.0M

UBS Group AG2,895,681

0.0% of portfolio$10.7M

Aberdeen Group plc2,819,129

0.0% of portfolio$10.4M

Squarepoint Ops LLC2,356,312

0.0% of portfolio$8.7M

Dimensional Fund Advisors LP1,595,027

0.0% of portfolio$5.9M

Y-Intercept (Hong Kong) Ltd1,382,476

0.1% of portfolio$5.1M

Emerald Advisers, LLC1,257,001

0.1% of portfolio$4.7M

Emerald Mutual Fund Advisers Trust844,388

0.1% of portfolio$3.1M

Nuveen, LLC436,778

0.0% of portfolio$1.6M

Bank of New York Mellon Corp419,369

0.0% of portfolio$1.6M

Profund Advisors LLC288,348

0.0% of portfolio$1.1M

Alps Advisors Inc261,053

0.0% of portfolio$965.9K

Russell Investments Group, Ltd.176,021

0.0% of portfolio$651.3K

Rhumbline Advisers175,787

0.0% of portfolio$650.4K

Deutsche Bank Ag\132,196

0.0% of portfolio$489.1K

Creative Planning121,467

0.0% of portfolio$449.4K

Zurcher Kantonalbank (Zurich Cantonalbank)108,886

0.0% of portfolio$402.9K

Connor, Clark & Lunn Investment Management Ltd.106,517

0.0% of portfolio$394.1K

Simplex Trading, LLC103,673

0.0% of portfolio$383.6K

James J. Burns & Company, LLC100,800

0.0% of portfolio$373.0K

LOS Angeles Capital Management LLC89,723

0.0% of portfolio$332.0K

Citigroup Inc85,436

0.0% of portfolio$316.1K

Handelsbanken Fonder AB81,900

0.0% of portfolio$303

Achmea Investment Management B.V.61,811

0.0% of portfolio$228.9K

Carolina Wealth Management Inc52,500

0.1% of portfolio$194.3K

Oppenheimer & Co Inc48,770

0.0% of portfolio$180.4K

AlphaCentric Advisors LLC45,624

0.1% of portfolio$168.8K

Exchange Traded Concepts, LLC44,641

0.0% of portfolio$165.2K

Savant Capital, LLC41,987

0.0% of portfolio$155.4K

State of New Jersey Common Pension Fund D41,982

0.0% of portfolio$155.3K

SEI Investments Co40,411

0.0% of portfolio$149.5K

Strs Ohio38,300

0.0% of portfolio$141.7K

Police & Firemen's Retirement System of New Jersey38,172

0.0% of portfolio$141.2K

Arizona State Retirement System36,588

0.0% of portfolio$135.4K

Mitsubishi UFJ Asset Management Co., Ltd.36,172

0.0% of portfolio$133.8K

Drive Wealth Management, LLC36,020

0.0% of portfolio$133.3K

China Universal Asset Management Co., Ltd.35,954

0.0% of portfolio$130.9K

Matisse Capital35,723

0.1% of portfolio$132.2K

Voya Investment Management LLC30,922

0.0% of portfolio$114.4K

FNY Investment Advisers, LLC30,000

0.0% of portfolio$111

Victory Capital Management Inc25,657

0.0% of portfolio$94.9K

ProShare Advisors LLC24,575

0.0% of portfolio$90.9K

KLP Kapitalforvaltning AS24,000

0.0% of portfolio$88.8K

Employees Retirement System of Texas23,871

0.0% of portfolio$88

Clear Harbor Asset Management, LLC20,000

0.0% of portfolio$74.0K

Pictet Asset Management Holding SA18,861

0.0% of portfolio$69.8K

HighTower Advisors, LLC16,797

0.0% of portfolio$62.1K

Bessemer Group Inc15,550

0.0% of portfolio$58

Pavaki Capital Management LLC15,000

0.0% of portfolio$55.5K

Vontobel Holding Ltd.14,000

0.0% of portfolio$51.8K

Xponance LLC13,024

0.0% of portfolio$48.2K

R Squared Ltd12,979

0.0% of portfolio$48.0K

Acadian Asset Management LLC12,641

0.0% of portfolio$46

Mirae Asset Global Investments Co., Ltd.10,069

0.0% of portfolio$37.3K

State of Wyoming8,223

0.0% of portfolio$30.4K

Group One Trading LLC7,873

0.0% of portfolio$29.1K

Parallel Advisors, LLC6,209

0.0% of portfolio$23.0K

GF Fund Management Co. Ltd.6,098

0.0% of portfolio$22.6K

Caitong International Asset Management Co., Ltd4,723

0.0% of portfolio$17.5K

Clearstead Advisors, LLC3,000

0.0% of portfolio$11.1K

Sterling Capital Management LLC2,890

0.0% of portfolio$10.7K

Capital Advisors, Ltd. LLC2,500

0.0% of portfolio$9

EverSource Wealth Advisors, LLC2,422

0.0% of portfolio$9.0K

Farther Finance Advisors, LLC2,148

0.0% of portfolio$7.9K

Signaturefd, LLC1,917

0.0% of portfolio$7.1K

Nisa Investment Advisors, LLC1,716

0.0% of portfolio$6.3K

Nykredit A/S1,442

0.0% of portfolio$5.3K

Versant Capital Management, Inc1,371

0.0% of portfolio$5.1K

Smartleaf Asset Management LLC1,156

0.0% of portfolio$4.2K

MassMutual Private Wealth & Trust, FSB1,050

0.0% of portfolio$3.9K

Global Retirement Partners, LLC739

0.0% of portfolio$2.7K

Gamma Investing LLC535

0.0% of portfolio$2.0K

TFC Financial Management, Inc.500

0.0% of portfolio$1.9K

Transce3nd, LLC500

0.0% of portfolio$1.7K

Parkside Financial Bank & Trust499

0.0% of portfolio$1.8K

Financial Consulate, Inc322

0.0% of portfolio$1.2K

PNC Financial Services Group, Inc.312

0.0% of portfolio$1.2K

Larson Financial Group LLC281

0.0% of portfolio$1.0K

Cornerstone Financial Management LLC190

0.0% of portfolio$703

US Bancorp \de\155

0.0% of portfolio$574

TD Private Client Wealth LLC146

0.0% of portfolio$540

Physician Wealth Advisors, Inc.103

0.0% of portfolio$382

SBI Securities Co., Ltd.75

0.0% of portfolio$278

SJS Investment Consulting Inc.75

0.0% of portfolio$278

Entrust Financial LLC75

0.0% of portfolio$278

Root Financial Partners, LLC33

0.0% of portfolio$122

Covestor Ltd26

0.0% of portfolio$0

Silver Grove Financial Group, Inc.23

0.0% of portfolio$85

IFP Advisors, Inc6

0.0% of portfolio$22

Hughes Financial Services, LLC1

0.0% of portfolio$4

				Style	Turnover	Location	Filed
GSK plc	18,245,691	$67.5M	13.6%	Deep Value	Low	London, United Kingdom	2026-11-05
FMR LLC	3,835,270	$14.2M	0.0%	Growth	Medium	Boston, MA	2026-11-10
Geode Capital Management, LLC	3,517,585	$13.0M	0.0%	Index	Very Low	Boston, MA	2026-11-06
UBS Group AG	2,895,681	$10.7M	0.0%	Core	Medium	Zurich, Switzerland	2026-11-10
Aberdeen Group plc	2,819,129	$10.4M	0.0%	Core	Medium	Edinburgh, United Kingdom	2026-11-10
Squarepoint Ops LLC	2,356,312	$8.7M	0.0%	Core	Very High	New York, NY	2026-11-09
Dimensional Fund Advisors LP	1,595,027	$5.9M	0.0%	Index	Low	Austin, TX	2026-11-04
Y-Intercept (Hong Kong) Ltd	1,382,476	$5.1M	0.1%	Value	Very High	Hong Kong, South Korea	2026-10-16
Emerald Advisers, LLC	1,257,001	$4.7M	0.1%	Growth	High	Leola, PA	2026-11-09
Emerald Mutual Fund Advisers Trust	844,388	$3.1M	0.1%	Growth	High	Leola, PA	2026-11-09
Nuveen, LLC	436,778	$1.6M	0.0%	Core	Low	Charlotte, NC	2026-11-10
Bank of New York Mellon Corp	419,369	$1.6M	0.0%	Core	Low	New York, NY	2026-11-05
Profund Advisors LLC	288,348	$1.1M	0.0%	Growth	Low	Bethesda, MD	2026-10-29
Alps Advisors Inc	261,053	$965.9K	0.0%	Yield	Low	Denver, CO	2026-11-03
Russell Investments Group, Ltd.	176,021	$651.3K	0.0%	Core	Low	Seattle, WA	2026-11-06
Rhumbline Advisers	175,787	$650.4K	0.0%	Index	Very Low	Boston, MA	2026-11-10
Deutsche Bank Ag\	132,196	$489.1K	0.0%	Core	Low	Frankfurt Am Main, Hong Kong	2026-11-06
Creative Planning	121,467	$449.4K	0.0%	Index	Very Low	Overland Park, KS	2026-11-02
Zurcher Kantonalbank (Zurich Cantonalbank)	108,886	$402.9K	0.0%	Core	Low	Zurich, Switzerland	2026-11-10
Connor, Clark & Lunn Investment Management Ltd.	106,517	$394.1K	0.0%	Core	High	Vancouver, UAE	2026-11-10
Simplex Trading, LLC	103,673	$383.6K	0.0%	GARP	Very High	Chicago, IL	2026-11-04
James J. Burns & Company, LLC	100,800	$373.0K	0.0%	ETF	Very Low	Melville, NY	2026-10-22
LOS Angeles Capital Management LLC	89,723	$332.0K	0.0%	Core	High	Los Angeles, CA	2026-11-10
Citigroup Inc	85,436	$316.1K	0.0%	Core	Medium	New York, NY	2026-11-04
Handelsbanken Fonder AB	81,900	$303	0.0%	Growth	Low	Stockholm, Sweden	2026-11-09
Achmea Investment Management B.V.	61,811	$228.9K	0.0%	Core	Medium	Zeist, Philippines	2026-10-30
Carolina Wealth Management Inc	52,500	$194.3K	0.1%	ETF	N/A	Greenville, NC	2026-10-29
Oppenheimer & Co Inc	48,770	$180.4K	0.0%	Core	Low	New York, NY	2026-10-26
AlphaCentric Advisors LLC	45,624	$168.8K	0.1%	Core	High	San Juan, PR	2026-11-03
Exchange Traded Concepts, LLC	44,641	$165.2K	0.0%	Growth	Medium	Oklahoma City, OK	2026-10-28
Savant Capital, LLC	41,987	$155.4K	0.0%	ETF	Low	Rockford, IL	2026-11-06
State of New Jersey Common Pension Fund D	41,982	$155.3K	0.0%	Index	Low	Trenton, NJ	2026-11-05
SEI Investments Co	40,411	$149.5K	0.0%	GARP	Low	Oaks, PA	2026-11-10
Strs Ohio	38,300	$141.7K	0.0%	Core	Medium	Columbus, OH	2026-10-30
Police & Firemen's Retirement System of New Jersey	38,172	$141.2K	0.0%	Index	Very Low	Trenton, NJ	2026-11-09
Arizona State Retirement System	36,588	$135.4K	0.0%	Index	Very Low	Phoenix, AZ	2026-11-03
Mitsubishi UFJ Asset Management Co., Ltd.	36,172	$133.8K	0.0%	Index	Very Low	Tokyo, Mexico	2026-11-05
Drive Wealth Management, LLC	36,020	$133.3K	0.0%	Core	Medium	Lehi, UT	2026-11-09
China Universal Asset Management Co., Ltd.	35,954	$130.9K	0.0%	Growth	Medium	Shanghai, France	2026-10-28
Matisse Capital	35,723	$132.2K	0.1%	Value	Medium	Portland, OR	2026-10-29
Voya Investment Management LLC	30,922	$114.4K	0.0%	Growth	Medium	Atlanta, GA	2026-11-10
FNY Investment Advisers, LLC	30,000	$111	0.0%	Growth	Very High	New York, NY	2026-10-16
Victory Capital Management Inc	25,657	$94.9K	0.0%	Core	Medium	San Antonio, TX	2026-11-10
ProShare Advisors LLC	24,575	$90.9K	0.0%	Growth	Low	Bethesda, MD	2026-10-29
KLP Kapitalforvaltning AS	24,000	$88.8K	0.0%	Index	Very Low	Oslo, Norway	2026-11-10
Employees Retirement System of Texas	23,871	$88	0.0%	Growth	Medium	Austin, TX	2026-11-10
Clear Harbor Asset Management, LLC	20,000	$74.0K	0.0%	Core	Low	Stamford, CT	2026-11-05
Pictet Asset Management Holding SA	18,861	$69.8K	0.0%	Growth	Medium	Carouge, Switzerland	2026-11-03
HighTower Advisors, LLC	16,797	$62.1K	0.0%	Index	Low	Chicago, IL	2026-11-10
Bessemer Group Inc	15,550	$58	0.0%	Core	Medium	Woodbridge, NJ	2026-11-09
Pavaki Capital Management LLC	15,000	$55.5K	0.0%	GARP	Medium	Pueblo, CO	2026-10-26
Vontobel Holding Ltd.	14,000	$51.8K	0.0%	Core	Medium	Zurich, Switzerland	2026-10-16
Xponance LLC	13,024	$48.2K	0.0%	Index	Very Low	Philadelphia, PA	2026-11-03
R Squared Ltd	12,979	$48.0K	0.0%	Value	Very High	Hong Kong, South Korea	2026-11-06
Acadian Asset Management LLC	12,641	$46	0.0%	GARP	Medium	Boston, MA	2026-11-09
Mirae Asset Global Investments Co., Ltd.	10,069	$37.3K	0.0%	Growth	Low	Seoul, Malaysia	2026-11-03
State of Wyoming	8,223	$30.4K	0.0%	Value	High	Cheyenne, WY	2026-10-28
Group One Trading LLC	7,873	$29.1K	0.0%	Value	Very High	Chicago, IL	2026-11-10
Parallel Advisors, LLC	6,209	$23.0K	0.0%	Growth	Low	San Francisco, CA	2026-11-03
GF Fund Management Co. Ltd.	6,098	$22.6K	0.0%	Agg Growth	Medium	Guangzhou, France	2026-10-26
Caitong International Asset Management Co., Ltd	4,723	$17.5K	0.0%	Growth	Very High	Hong Kong, South Korea	2026-10-29
Clearstead Advisors, LLC	3,000	$11.1K	0.0%	ETF	Low	Cleveland, OH	2026-11-06
Sterling Capital Management LLC	2,890	$10.7K	0.0%	Core	Medium	Charlotte, NC	2026-10-22
Capital Advisors, Ltd. LLC	2,500	$9	0.0%	ETF	Low	Shaker Heights, OH	2026-10-27
EverSource Wealth Advisors, LLC	2,422	$9.0K	0.0%	Core	Medium	Birmingham, AL	2026-11-04
Farther Finance Advisors, LLC	2,148	$7.9K	0.0%	Index	Low	San Francisco, CA	2026-10-08
Signaturefd, LLC	1,917	$7.1K	0.0%	Index	Low	Atlanta, GA	2026-10-23
Nisa Investment Advisors, LLC	1,716	$6.3K	0.0%	Index	Very Low	St. Louis, MO	2026-10-20
Nykredit A/S	1,442	$5.3K	0.0%	Core	N/A	Nordhavn, Greece	2026-11-06
Versant Capital Management, Inc	1,371	$5.1K	0.0%	Core	Low	Phoenix, AZ	2026-10-02
Smartleaf Asset Management LLC	1,156	$4.2K	0.0%	Index	Very Low	Boston, MA	2026-11-10
MassMutual Private Wealth & Trust, FSB	1,050	$3.9K	0.0%	Core	Low	Springfield, MA	2026-10-05
Global Retirement Partners, LLC	739	$2.7K	0.0%	Core	Low	San Rafael, CA	2026-11-10
Gamma Investing LLC	535	$2.0K	0.0%	Index	Very Low	Foster City, CA	2026-10-08
TFC Financial Management, Inc.	500	$1.9K	0.0%	ETF	Very Low	Boston, MA	2026-10-26
Transce3nd, LLC	500	$1.7K	0.0%	Growth	Low	Buda, TX	2026-10-26
Parkside Financial Bank & Trust	499	$1.8K	0.0%	Core	Very Low	Saint Louis, MO	2026-10-27
Financial Consulate, Inc	322	$1.2K	0.0%	ETF	Low	Hunt Valley, MD	2026-10-23
PNC Financial Services Group, Inc.	312	$1.2K	0.0%	Growth	Very Low	Pittsburgh, PA	2026-11-06
Larson Financial Group LLC	281	$1.0K	0.0%	Growth	Low	St Louis, MO	2026-11-05
Cornerstone Financial Management LLC	190	$703	0.0%	Index	Very Low	Burlington, MA	2026-11-10
US Bancorp \de\	155	$574	0.0%	Core	Low	Minneapolis, MN	2026-11-05
TD Private Client Wealth LLC	146	$540	0.0%	ETF	Low	New York, NY	2026-10-28
Physician Wealth Advisors, Inc.	103	$382	0.0%	ETF	Medium	Midvale, UT	2026-10-20
SBI Securities Co., Ltd.	75	$278	0.0%	Growth	Low	Tokyo, Mexico	2026-10-22
SJS Investment Consulting Inc.	75	$278	0.0%	ETF	Very Low	Sylvania, OH	2026-10-26
Entrust Financial LLC	75	$278	0.0%	ETF	Medium	Wayne, PA	2026-11-04
Root Financial Partners, LLC	33	$122	0.0%	ETF	Medium	Encinitas, CA	2026-10-21
Covestor Ltd	26	$0	0.0%	Value	High	London, United Kingdom	2026-10-30
Silver Grove Financial Group, Inc.	23	$85	0.0%	Core	Low	Orchard Park, NY	2026-11-05
IFP Advisors, Inc	6	$22	0.0%	Core	Low	Tampa, FL	2026-10-16
Hughes Financial Services, LLC	1	$4	0.0%	ETF	Low	Herndon, VA	2026-10-30