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Two Sigma Investments, LP

Q4 2025 Holdings

Filed 2026-02-17 | 4041 holdings | $70.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↑Shares% Portfolio
Rein Therapeutics Inc(RNTX)COM NEW00887A204$48.4K41,7090.0%
Ribbon Communications Inc(RBBN)COM762544104$48.9K16,9840.0%
Zhihu Inc(ZH)SPONSORED ADS98955N207$49.5K15,1000.0%
Cleancore Solutions Inc(ZONE)CLASS B COM SHS184492106$49.9K192,0350.0%
EON Resources Inc(EONR)COM CL A40472A102$50.5K131,3560.0%
Twin VEE Powercats Co(VEEE)COM NEW90177C200$51.1K29,3940.0%
Envveno Medical CorporationCOM29415J106$51.2K159,6190.0%
Mega Matrix Inc(MPU)CL A ORD SHSG6005C108$51.2K56,3040.0%
Solarmax Technology Inc(SMXT)COM SHS83419H103$51.2K62,4280.0%
Unisys Corp(UIS)COM NEW909214306$51.3K18,5710.0%
Eightco Holdings Inc(ORBS)COM22890A302$52.0K30,0610.0%
Medicinova Inc(MNOV)COM NEW58468P206$52.1K39,7360.0%
Indonesia Energy Corp LTD(INDO)ORD SHSG4760X102$52.3K17,8380.0%
Cyclerion Therapeutics Inc(CYCN)COM23255M204$52.8K41,5550.0%
Flux PWR Hldgs Inc(FLUX)COM NEW344057302$54.4K42,8520.0%
Troops Inc(TROO)SHSG9094C104$54.6K17,0710.0%
Intrusion Inc(INTZ)COM46121E304$55.1K47,8990.0%
Smart Digital Group LTDORD SHSG5006S104$56.5K30,5170.0%
Surgepays Inc(SURG)COM NEW86882L204$56.6K33,8710.0%
Presurance Holdings Inc(PRHI)COM20731J102$57.0K79,9430.0%
Destination XL Group Inc(DXLG)COM25065K104$58.2K63,2590.0%
Dawson Geophysical Co New(DWSN)COM239360100$58.4K37,4160.0%
Authid Inc(AUID)COM46264C305$58.7K67,0760.0%
Interlink Electrs Inc(LINK)COM NEW458751302$59.1K15,2420.0%
Lixte Biotechnology Hldgs in(LIXT)COM539319301$59.6K15,1740.0%
FG Nexus Inc.COM NEW30329Y304$59.9K21,7800.0%
Alaunos Therapeutics Inc(TCRT)COM NEW98973P309$60.0K18,5880.0%
Mogo Inc(DCFEUR)COM60800C208$60.6K56,6330.0%
Cineverse Corp(CNVS)COM CL A172406308$61.7K29,2450.0%
Bionano Genomics Inc(BNGO)COM09075F404$62.0K40,5130.0%
Pasithea Therapeutics Corp(KTTA)COM NEW70261F202$62.9K48,7730.0%
Westrock Coffee Co(WEST)COM96145W103$63.1K15,4940.0%
Siga Technologies Inc(SIGA)COM826917106$63.5K10,4000.0%
Arrive AI Inc(ARAI)COM NEW04272H204$63.7K24,2270.0%
Dare Bioscience Inc(DARE)COM NEW23666P200$63.8K33,0360.0%
Cognition Therapeutics Inc(CGTX)COM19243B102$64.4K47,7290.0%
Sera Prognostics Inc(SERA)CLASS A COM81749D107$64.8K21,9640.0%
Codexis Inc(CDXS)COM192005106$64.9K39,8040.0%
Aquabounty Technologies Inc(AQB)COM03842K309$64.9K69,7890.0%
Palisade BIO Inc(PALI)COM696389402$65.0K27,6400.0%
Alta Equipment Group Inc(ALTG)COMMON STOCK02128L106$65.1K14,1480.0%
Sunrise New Energy Co LTDORD CL A SHSG3932F106$66.0K67,3040.0%
In8bio Inc(INAB)COM NEW45674E208$66.0K28,2140.0%
Intelligent Protection Manag(IPM)COM69764K106$66.5K38,6770.0%
Kairos Pharma LTD(KAPA)COM48301N104$66.7K94,0080.0%
Castellum Inc(CTM)COM NEW14838T204$68.1K75,3840.0%
X4 Pharmaceuticals Inc(XFOR)COM NEW98420X202$69.0K17,2460.0%
Galectin Therapeutics Inc(GALT)COM NEW363225202$69.1K16,6120.0%
Aeye Inc(LIDR)CL A NEW008183204$69.9K38,0120.0%
Traeger Inc(COOK)COMMON STOCK89269P103$70.9K65,6360.0%
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