| Ardelyx Inc CMN(ARDX) | COM | 039697107 | $194.0K | 15,000 | 33.1% |
| Vanda Pharmaceuticals Inc. CMN(VNDA) | COM | 921659108 | $45.0K | 2,706,134 | 7.7% |
| Adamas Pharmaceuticals Inc CMN(ADMSEUR) | COM | 00548A106 | $42.7K | 2,601,351 | 7.3% |
| Synergy Pharmaceuticals Inc CMN | COM | 871639308 | $35.4K | 6,422,232 | 6.0% |
| Zogenix Inc CMN | COM | 98978L204 | $27.9K | 2,440,959 | 4.8% |
| Foamix Pharmaceuticals Limited CMN | COM | M46135105 | $25.6K | 2,769,425 | 4.4% |
| Dermira Inc CMN(DERMEUR) | COM | 24983L104 | $23.0K | 679,403 | 3.9% |
| Ignyta Inc CMN | COM | 451731103 | $21.9K | 3,475,227 | 3.7% |
| Enanta Pharmaceuticals Inc CMN(ENTA) | COM | 29251M106 | $21.0K | 790,000 | 3.6% |
| Neurocrine Biosciences Inc CMN(NBIX) | COM | 64125C109 | $20.0K | 394,080 | 3.4% |
| Avexis Inc CMN | COM | 05366U100 | $15.7K | 381,095 | 2.7% |
| Merrimack Pharmaceuticals Inc CMN | COM | 590328100 | $15.5K | 2,442,159 | 2.6% |
| Colucid Pharmaceuticals Inc CMN | COM | 19716T101 | $15.3K | 400,000 | 2.6% |
| Bovie Medical Corporation CMN | COM | 10211F100 | $14.0K | 2,680,000 | 2.4% |
| Sage Therapeutics, Inc CMN(SG7) | COM | 78667J108 | $12.2K | 264,893 | 2.1% |
| Connecture Inc | COM | 20786J106 | $7.8K | 4,127,232 | 1.3% |
| Aradigm Corp CMN(ARDMEUR) | COM | 038505400 | $6.9K | 1,002,962 | 1.2% |
| Ocera Therapeutics Inc CMN Class | COM | 67552A108 | $5.2K | 1,963,777 | 0.9% |
| DBV Technologies SA Sponsored ADR CMN | COM | 23306J101 | $4.8K | 131,452 | 0.8% |
| Sunesis Pharmaceuticals Inc CMN | COM | 867328700 | $4.6K | 1,063,573 | 0.8% |
| Alimera Sciences CMN | COM | 016259103 | $3.9K | 2,637,969 | 0.7% |
| PUT @ 5 EXP 03/17/2017(BCRX)Put | PUT | 09058V103 | $3.2K | 725,000 | 0.5% |
| PUT @ 95 EXP 10/21/2016Put | PUT | 36197T103 | $3.2K | 23,800 | 0.5% |
| Dipexium Pharmaceuticals Inc CMN | COM | 25456J104 | $2.6K | 178,930 | 0.4% |
| Tenax Therapeutics Inc CMN | COM | 88032L100 | $2.6K | 1,108,593 | 0.4% |
| PDL Biopharma Inc CMN(PDLI) | COM | 69329Y104 | $2.2K | 645,000 | 0.4% |
| Tetraphase Pharmaceuticals Inc CMN | COM | 88165N105 | $1.7K | 452,375 | 0.3% |
| Catabasis Pharmaceuticals, Inc CMN | COM | 14875P107 | $1.5K | 250,000 | 0.3% |
| Mirati Therapeutics Inc CMN(MRTXEUR) | COM | 60468T105 | $1.5K | 227,657 | 0.3% |
| Seres Therapeutics, Inc. CMN(MCRB1EUR) | COM | 81750R102 | $1.5K | 120,000 | 0.3% |
| PUT @ 20 EXP 10/21/2016(MCRB1EUR)Put | PUT | 81750R102 | $1.5K | 120,000 | 0.3% |
| Inotek Pharmaceuticals Corp CMN | COM | 45780V102 | $892 | 94,077 | 0.2% |
| Call @ 8 EXP 10/21/2016Call | CALL | 670002104 | $851 | 409,200 | 0.1% |
| Streamline Health Solutns, Inc CMN | COM | 86323X106 | $279 | 151,611 | 0.0% |
| Call @ 80 EXP 01/20/2017Call | CALL | 683745103 | $157 | 3,400 | 0.0% |