Q4 2019 Holdings
Filed 2020-02-14 | 99 holdings | $5.3B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $2.0B | 11,777,285 | 37.2% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $1.7B | 40,854,586 | 33.3% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $641.7M | 7,589,294 | 12.2% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $471.7M | 3,390,270 | 9.0% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $163.7M | 1,019,557 | 3.1% |
| Axsome Therapeutics, Inc.(AXSM) | COM | 05464T104 | $85.8M | 829,757 | 1.6% |
| Cerus Corporation(CERS) | COM | 157085101 | $45.4M | 10,749,937 | 0.9% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $37.8M | 10,946,166 | 0.7% |
| Aurinia Pharmaceuticals Inc.(AUPH) | COM | 05156V102 | $34.5M | 1,701,929 | 0.7% |
| Adaptive Biotechnologies Corporation(ADPT) | COM | 00650F109 | $33.4M | 1,115,411 | 0.6% |
| Cabaletta Bio, Inc.(CABA) | COM | 12674W109 | $8.9M | 636,363 | 0.2% |
| Seattle Genetics, Inc. | COM | 812578102 | $5.7M | 50,057,277 | 0.1% |
| Catalyst Pharmaceuticals, Inc.(CPRX) | COM | 14888U101 | $5.0M | 1,341,902 | 0.1% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $4.4M | 175,000 | 0.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.8M | 31,976,873 | 0.1% |
| Autolus Therapeutics plc(AUTL) | SPONSORED ADS | 05280R100 | $2.1M | 156,773 | 0.0% |
| CytomX Therapeutics, Inc.(CTMX) | COM | 23284F105 | $1.6M | 194,377 | 0.0% |
| Arcus Biosciences, Inc.(RCUS) | COM | 03969F109 | $1.2M | 121,534 | 0.0% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $893.1K | 8,258,068 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $794.9K | 11,047,289 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $739.6K | 34,496,685 | 0.0% |
| Exact Sciences Corporation(EXAS) | COM | 30063P105 | $239.1K | 2,585,791 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $168.4K | 1,307,220 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $156.4K | 14,614,264 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $146.7K | 9,097,165 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $141.4K | 6,018,104 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $134.8K | 1,254,243 | 0.0% |
| MyoKardia, Inc. | COM | 62857M105 | $129.3K | 1,774,234 | 0.0% |
| IGM Biosciences, Inc.(1K0) | COM | 449585108 | $120.0K | 3,144,000 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $106.5K | 1,169,278 | 0.0% |
| Ra Pharmaceuticals, Inc. | COM | 74933V108 | $98.3K | 2,093,839 | 0.0% |
| Principia Biopharma Inc.(PRNB) | COM | 74257L108 | $97.9K | 1,787,957 | 0.0% |
| Zymeworks Inc. | COM | 98985W102 | $77.7K | 1,708,472 | 0.0% |
| Tricida, Inc.(1T7) | COM | 89610F101 | $74.3K | 1,969,905 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $62.2K | 2,708,200 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $58.4K | 2,445,265 | 0.0% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $57.3K | 1,034,674 | 0.0% |
| Atreca, Inc.(BCELUSD) | CL A Common | 04965G109 | $54.7K | 3,532,760 | 0.0% |
| Audentes Therapeutics, Inc.(BOLDEUR) | COM | 05070R104 | $48.2K | 804,720 | 0.0% |
| Neurocrine Biosciences, Inc. | NOTE 2.25% 5/15/2024 | 64125CAD1 | $47.1K | $30,770,000 | 0.0% |
| Neoleukin Therapeutics, Inc. | COM | 64049K104 | $41.9K | 3,397,740 | 0.0% |
| GW Pharmaceuticals plc | ADS | 36197T103 | $38.8K | 370,845 | 0.0% |
| uniQure N.V.(QURE) | SHS | N90064101 | $37.1K | 517,700 | 0.0% |
| Allakos Inc.(ALLKGUSD) | COM | 01671P100 | $32.4K | 339,690 | 0.0% |
| Assembly Biosciences, Inc. | COM | 045396108 | $31.5K | 1,541,618 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $31.0K | 2,799,577 | 0.0% |
| ChemoCentryx, Inc.(CCXIEUR) | COM | 16383L106 | $29.2K | 739,016 | 0.0% |
| Merus N.V. | COM | N5749R100 | $28.7K | 2,037,469 | 0.0% |
| UroGen Pharma Ltd.(URGN) | COM | M96088105 | $27.7K | 831,488 | 0.0% |
| Aimmune Therapeutics, Inc.(AIMT) | COM | 00900T107 | $22.6K | 673,908 | 0.0% |