Q4 2020 Holdings
Filed 2021-02-16 | 126 holdings | $7.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $3.0B | 11,668,897 | 39.4% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $2.2B | 41,904,586 | 29.3% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $665.5M | 7,589,294 | 8.7% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $590.4M | 3,540,270 | 7.7% |
| AbCellera Biologics Inc.(ABCL) | COM | 00288U106 | $420.5M | 10,450,180 | 5.5% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $299.8M | 1,019,557 | 3.9% |
| Cerus Corporation(CERS) | COM | 157085101 | $94.9M | 13,713,195 | 1.2% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $94.6M | 12,695,818 | 1.2% |
| Axsome Therapeutics, Inc.(AXSM) | COM | 05464T104 | $63.5M | 778,834 | 0.8% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $53.0M | 9,830,877 | 0.7% |
| Adaptive Biotechnologies Corporation(ADPT) | COM | 00650F109 | $22.5M | 379,682 | 0.3% |
| Altimmune, Inc.(ALT) | COM | 02155H200 | $21.3M | 1,884,451 | 0.3% |
| Aurinia Pharmaceuticals Inc.(AUPH) | COM | 05156V102 | $19.5M | 1,410,064 | 0.3% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $8.7M | 616,520 | 0.1% |
| Seagen Inc.(SGENUSD) | COM | 81181C104 | $8.3M | 47,269,424 | 0.1% |
| Cabaletta Bio, Inc.(CABA) | COM | 12674W109 | $7.9M | 636,363 | 0.1% |
| Autolus Therapeutics plc(AUTL) | SPONSORED ADS | 05280R100 | $7.0M | 782,183 | 0.1% |
| Alector, Inc.(ALEC) | COM | 014442107 | $3.6M | 239,228 | 0.0% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.8M | 31,999,741 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $2.0M | 13,879,952 | 0.0% |
| Arcus Biosciences, Inc.(RCUS) | COM | 03969F109 | $1.9M | 72,709 | 0.0% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $1.4M | 8,760,794 | 0.0% |
| Prelude Therapeutics Incorporated(PRLD) | COM | 74065P101 | $724.0K | 10,118,636 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $654.3K | 15,649,182 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $309.6K | 1,409,784 | 0.0% |
| IGM Biosciences, Inc.(1K0) | COM | 449585108 | $277.7K | 3,144,892 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $166.7K | 1,499,213 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $136.9K | 27,991,761 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $126.9K | 5,994,704 | 0.0% |
| Kymera Therapeutics, Inc.(KYMR) | COM | 501575104 | $121.5K | 1,959,211 | 0.0% |
| Allakos Inc.(ALLKGUSD) | COM | 01671P100 | $100.0K | 714,250 | 0.0% |
| Pacific Biosciences of California, Inc.(PACB) | COM | 69404D108 | $83.1K | 3,201,972 | 0.0% |
| Zymeworks Inc. | COM | 98985W102 | $80.7K | 1,708,472 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $71.8K | 2,156,001 | 0.0% |
| Forma Therapeutics Holdings, Inc. | SHS | 34633R104 | $70.7K | 2,024,876 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $68.8K | 2,314,873 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $64.9K | 676,975 | 0.0% |
| Ultragenyx Pharmaceutical Inc.(RARE) | COM | 90400D108 | $61.5K | 444,444 | 0.0% |
| Nurix Therapeutics, Inc.(NRIX) | COM | 67080M103 | $58.8K | 1,788,921 | 0.0% |
| Atreca, Inc.(BCELUSD) | CL A COM | 04965G109 | $57.1K | 3,532,760 | 0.0% |
| Neoleukin Therapeutics, Inc. | COM | 64049K104 | $53.9K | 3,821,740 | 0.0% |
| Apellis Pharmaceuticals, Inc.(APLS) | COM | 03753U106 | $51.3K | 896,551 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $49.5K | 2,799,577 | 0.0% |
| ADC Therapeutics SA(ADCT) | SHS | H0036K147 | $45.4K | 1,418,107 | 0.0% |
| Aligos Therapeutics, Inc. | COM | 01626L105 | $44.5K | 1,610,000 | 0.0% |
| Horizon Therapeutics Public Ltd Co | SHS | G46188101 | $43.8K | 599,110 | 0.0% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $41.9K | 698,874 | 0.0% |
| ChemoCentryx, Inc.(CCXIEUR) | COM | 16383L106 | $40.7K | 656,710 | 0.0% |
| Global Blood Therapeutics, Inc. | COM | 37890U108 | $39.9K | 920,375 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $38.3K | 14,614,264 | 0.0% |