Q3 2021 Holdings
Filed 2021-11-15 | 52 holdings | $1.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Ascendis Pharma(ASND) | Sponsored ADR | 04351P101 | $315.6M | 1,980,000 | 30.8% |
| Argenx SE(ARGX) | Sponsored ADR | 04016X101 | $285.8M | 946,500 | 27.9% |
| Alnylam Pharmaceuticals Inc(ALNY) | Common | 02043Q107 | $160.5M | 850,000 | 15.6% |
| Biomarin Pharmaceutical Inc(BMRN) | Common | 09061G101 | $144.9M | 1,875,000 | 14.1% |
| Aadi Biosciences Inc(WHWK) | Common | 00032Q104 | $53.7M | 1,829,402 | 5.2% |
| Acadia Pharmaceuticals Inc(ACAD) | Common | 004225108 | $36.5M | 2,200,000 | 3.6% |
| Biogen Inc(BIIB) | Common | 09062X103 | $23.8M | 84,000 | 2.3% |
| Horizon Therapeutics PLC | Common | G46188101 | $985.9K | 9,000,000 | 0.1% |
| Mirati Therapeutics Inc(MRTXEUR) | Common | 60468T105 | $884.6K | 5,000,000 | 0.1% |
| Acceleron Pharma Inc(XLRN) | Common | 00434H108 | $688.4K | 4,000,000 | 0.1% |
| United Therapeutics Corp(UTHR) | Common | 91307C102 | $553.7K | 3,000,000 | 0.1% |
| Sarepta Therapeutics Inc(SRPT) | Common | 803607100 | $231.2K | 2,500,000 | 0.0% |
| Iovance Biotherapeutics Inc(IOVA) | Common | 462260100 | $209.6K | 8,500,000 | 0.0% |
| Arena Pharmaceuticals Inc(ARNAEUR) | Common | 040047607 | $204.0K | 3,425,000 | 0.0% |
| Amicus Therapeutics Inc(FOLD) | Common | 03152W109 | $168.8K | 17,679,273 | 0.0% |
| Apellis Pharmaceuticals Inc(APLS) | Common | 03753U106 | $164.8K | 5,000,000 | 0.0% |
| Vertex Pharmaceuticals Inc(VRTX) | Common | 92532F100 | $120.4K | 664,000 | 0.0% |
| Iveric BIO Inc(OPHTEUR) | Common | 46583P102 | $115.3K | 7,100,000 | 0.0% |
| Madrigal Pharmaceuticals Inc(MDGL) | Common | 558868105 | $113.7K | 1,425,000 | 0.0% |
| Trillium Therapeutics Inc | Common | 89620X506 | $100.1K | 5,700,000 | 0.0% |
| PMV Pharmaceuticals Inc(PMVP) | Common | 69353Y103 | $87.2K | 2,925,000 | 0.0% |
| Kura Oncology Inc(KURA) | Common | 50127T109 | $74.9K | 4,000,000 | 0.0% |
| Mersana Therapeutics Inc | Common | 59045L106 | $64.1K | 6,800,000 | 0.0% |
| Monte Rosa Therapeutics Inc(GLUE) | Common | 61225M102 | $61.0K | 3,311,434 | 0.0% |
| Xenon Pharmaceuticals Inc(XENE) | Common | 98420N105 | $55.8K | 3,650,000 | 0.0% |
| Mannkind Corp(MNKD) | Common | 56400P706 | $38.3K | 8,800,000 | 0.0% |
| Cymabay Therapeutics Inc(CBAYUSD) | Common | 23257D103 | $37.6K | 10,300,000 | 0.0% |
| Marinus Pharmaceuticals Inc(MRNS*) | Common | 56854Q200 | $36.8K | 3,235,000 | 0.0% |
| Deciphera Pharmaceuticals Inc(DCPHEUR) | Common | 24344T101 | $36.3K | 1,068,000 | 0.0% |
| Amarin Corp PLC | Sponsored ADR | 023111206 | $30.6K | 6,000,000 | 0.0% |
| Praxis Precision Medicines Inc | Common | 74006W108 | $29.6K | 1,600,000 | 0.0% |
| Syndax Pharmaceuticals Inc(SNDX) | Common | 87164F105 | $29.5K | 1,545,000 | 0.0% |
| Avidity Biosciences Inc(RNA) | Common | 05370A108 | $28.3K | 1,150,000 | 0.0% |
| Kymera Therapeutics Inc(KYMR) | Common | 501575104 | $26.8K | 455,750 | 0.0% |
| Dice Therapeutics Inc | Common | 23345J104 | $26.2K | 800,000 | 0.0% |
| Avadel Pharmaceuticals PLC | Sponsored ADR | 05337M104 | $22.3K | 2,275,000 | 0.0% |
| Nuvalent Inc(NUVL) | Common | 670703107 | $22.3K | 1,257,671 | 0.0% |
| Design Therapeutics Inc(DSGN) | Common | 25056L103 | $21.6K | 1,468,318 | 0.0% |
| Tango Therapeutics Inc(TNGX) | Common | 87583X109 | $20.0K | 1,550,000 | 0.0% |
| Fennec Pharmaceuticals Inc(FENC) | Common | 31447P100 | $15.7K | 1,670,000 | 0.0% |
| Adverum Biotechnologies Inc(ADVMCHF) | Common | 00773U108 | $15.1K | 6,950,000 | 0.0% |
| Merus N V | Common | N5749R100 | $9.9K | 450,000 | 0.0% |
| Genocea Biosciences Inc(GNCAQ) | Common | 372427401 | $9.8K | 5,084,184 | 0.0% |
| Sarepta Therapeutics Inc(SRPT)Call | Common | 803607100 | $2.2K | 200,000 | 0.0% |
| Iovance Biotherapeutics Inc(IOVA)Call | Common | 462260100 | $1.5K | 650,000 | 0.0% |
| Apellis Pharmaceuticals Inc(APLS)Call | Common | 03753U106 | $1.3K | 1,515,000 | 0.0% |
| Acceleron Pharma Inc(XLRN)Call | Common | 00434H108 | $32 | 476,100 | 0.0% |