Q3 2021 Holdings
Filed 2021-11-15 | 122 holdings | $7.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $4.2B | 11,668,897 | 58.7% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $723.9M | 4,541,604 | 10.0% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $696.1M | 41,910,704 | 9.7% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $589.0M | 7,620,494 | 8.2% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $338.1M | 1,119,557 | 4.7% |
| AbCellera Biologics Inc.(ABCL) | COM | 00288U106 | $209.4M | 10,450,180 | 2.9% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $182.7M | 12,710,818 | 2.5% |
| Cerus Corporation(CERS) | COM | 157085101 | $83.5M | 13,713,195 | 1.2% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $50.8M | 9,830,877 | 0.7% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $19.4M | 920,656 | 0.3% |
| Axsome Therapeutics, Inc.(AXSM) | COM | 05464T104 | $17.8M | 539,057 | 0.2% |
| Altimmune, Inc.(ALT) | COM | 02155H200 | $12.1M | 1,072,038 | 0.2% |
| Aurinia Pharmaceuticals Inc.(AUPH) | COM | 05156V102 | $11.5M | 520,523 | 0.2% |
| Cabaletta Bio, Inc.(CABA) | COM | 12674W109 | $8.1M | 662,063 | 0.1% |
| Seagen Inc.(SGENUSD) | COM | 81181C104 | $8.0M | 47,288,259 | 0.1% |
| Biomea Fusion, Inc.(BMEA) | COM | 09077A106 | $6.3M | 524,617 | 0.1% |
| aTyr Pharma, Inc.(ATYR) | COM | 002120202 | $5.7M | 625,000 | 0.1% |
| Alector, Inc.(ALEC) | COM | 014442107 | $5.5M | 239,228 | 0.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.2M | 32,022,125 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $1.4M | 14,681,304 | 0.0% |
| Prelude Therapeutics Inc.(PRLD) | COM | 74065P101 | $316.4K | 10,123,824 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $280.7K | 9,873,488 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $249.4K | 1,409,784 | 0.0% |
| IGM Biosciences, Inc.(1K0) | COM | 449585108 | $207.5K | 3,156,102 | 0.0% |
| Kymera Therapeutics, Inc.(KYMR) | COM | 501575104 | $140.1K | 2,384,742 | 0.0% |
| Pacific Biosciences of California, Inc.(PACB) | COM | 69404D108 | $139.1K | 5,444,963 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $119.6K | 1,499,213 | 0.0% |
| Legend Biotech Corporation(LEGN) | SPONSORED ADS | 52490G102 | $119.5K | 2,364,003 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $111.5K | 21,856,032 | 0.0% |
| Immunocore Holdings plc(IMCR) | ADS | 45258D105 | $93.4K | 2,520,730 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $86.9K | 8,131,678 | 0.0% |
| Global Blood Therapeutics, Inc. | COM | 37890U108 | $82.0K | 3,217,441 | 0.0% |
| Allakos Inc.(ALLKGUSD) | COM | 01671P100 | $74.4K | 703,050 | 0.0% |
| Nurix Therapeutics, Inc.(NRIX) | COM | 67080M103 | $73.5K | 2,454,082 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $71.6K | 14,614,264 | 0.0% |
| Instil Bio, Inc. | COM | 45783C101 | $69.6K | 3,893,700 | 0.0% |
| Verve Therapeutics, Inc. | COM | 92539P101 | $66.6K | 1,416,530 | 0.0% |
| Verastem, Inc. | COM | 92337C104 | $66.2K | 21,491,630 | 0.0% |
| Horizon Therapeutics Public Ltd Co | SHS | G46188101 | $65.6K | 599,110 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $64.9K | 676,975 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $59.4K | 2,156,001 | 0.0% |
| Immatics N.V.(IMTX) | SHS | N44445109 | $57.5K | 4,423,731 | 0.0% |
| Apellis Pharmaceuticals, Inc. | Note 3.5% 9/15/2026 | 03753UAB2 | $57.3K | $46,754,000 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $50.5K | 3,863,239 | 0.0% |
| Zymeworks Inc. | COM | 98985W102 | $49.6K | 1,708,472 | 0.0% |
| Travere Therapeutics, Inc.(TVTX) | COM | 89422G107 | $49.5K | 2,039,772 | 0.0% |
| bluebird bio, Inc. | COM | 09609G100 | $47.8K | 2,499,715 | 0.0% |
| Talis Biomedical Corporation | COM | 87424L108 | $47.3K | 7,574,835 | 0.0% |
| Forma Therapeutics Holdings, Inc. | SHS | 34633R104 | $47.0K | 2,024,876 | 0.0% |
| Merus N.V. | COM | N5749R100 | $44.8K | 2,037,469 | 0.0% |