Q4 2021 Holdings
Filed 2022-02-14 | 41 holdings | $1.1B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Argenx SE(ARGX) | Sponsored ADR | 04016X101 | $337.9M | 965,000 | 29.7% |
| Ascendis Pharma(ASND) | Sponsored ADR | 04351P101 | $269.1M | 2,000,000 | 23.7% |
| Biomarin Pharmaceutical Inc(BMRN) | Common | 09061G101 | $247.4M | 2,800,000 | 21.8% |
| Alnylam Pharmaceuticals Inc(ALNY) | Common | 02043Q107 | $182.3M | 1,075,000 | 16.0% |
| Acadia Pharmaceuticals Inc(ACAD) | Common | 004225108 | $51.3M | 2,200,000 | 4.5% |
| Aadi Biosciences Inc(WHWK) | Common | 00032Q104 | $44.2M | 1,829,402 | 3.9% |
| Horizon Therapeutics PLC | Common | G46188101 | $1.0M | 9,295,000 | 0.1% |
| Mirati Therapeutics Inc(MRTXEUR) | Common | 60468T105 | $744.5K | 5,075,000 | 0.1% |
| United Therapeutics Corp(UTHR) | Common | 91307C102 | $655.8K | 3,035,000 | 0.1% |
| Apellis Pharmaceuticals Inc(APLS) | Common | 03753U106 | $404.5K | 8,555,555 | 0.0% |
| Sarepta Therapeutics Inc(SRPT) | Common | 803607100 | $281.4K | 3,125,000 | 0.0% |
| Amicus Therapeutics Inc(FOLD) | Common | 03152W109 | $213.7K | 18,500,000 | 0.0% |
| Iovance Biotherapeutics Inc(IOVA) | Common | 462260100 | $165.6K | 8,675,000 | 0.0% |
| Xenon Pharmaceuticals Inc(XENE) | Common | 98420N105 | $155.7K | 4,985,000 | 0.0% |
| Iveric BIO Inc(OPHTEUR) | Common | 46583P102 | $121.2K | 7,250,000 | 0.0% |
| Madrigal Pharmaceuticals Inc(MDGL) | Common | 558868105 | $120.8K | 1,425,000 | 0.0% |
| Spdr Series Trust - S&P Biotech(XBI) | ETF | 78464A870 | $117.6K | 1,050,000 | 0.0% |
| Arena Pharmaceuticals Inc(ARNAEUR) | Common | 040047607 | $114.8K | 1,235,000 | 0.0% |
| Monte Rosa Therapeutics Inc(GLUE) | Common | 61225M102 | $67.6K | 3,311,434 | 0.0% |
| Kura Oncology Inc(KURA) | Common | 50127T109 | $56.0K | 4,000,000 | 0.0% |
| Syndax Pharmaceuticals Inc(SNDX) | Common | 87164F105 | $47.6K | 2,175,000 | 0.0% |
| Mersana Therapeutics Inc | Common | 59045L106 | $42.3K | 6,800,000 | 0.0% |
| Mannkind Corp(MNKD) | Common | 56400P706 | $38.5K | 8,800,000 | 0.0% |
| Marinus Pharmaceuticals Inc(MRNS*) | Common | 56854Q200 | $38.4K | 3,235,000 | 0.0% |
| Praxis Precision Medicines Inc | Common | 74006W108 | $35.1K | 1,780,000 | 0.0% |
| Design Therapeutics Inc(DSGN) | Common | 25056L103 | $35.0K | 1,636,100 | 0.0% |
| Kymera Therapeutics Inc(KYMR) | Common | 501575104 | $34.9K | 550,000 | 0.0% |
| Cymabay Therapeutics Inc(CBAYUSD) | Common | 23257D103 | $34.8K | 10,300,000 | 0.0% |
| PMV Pharmaceuticals Inc(PMVP) | Common | 69353Y103 | $33.8K | 1,465,000 | 0.0% |
| Krystal Biotech Inc(KRYS) | Common | 501147102 | $33.2K | 475,000 | 0.0% |
| Avidity Biosciences Inc(RNA) | Common | 05370A108 | $29.2K | 1,230,000 | 0.0% |
| Amarin Corp PLC | Sponsored ADR | 023111206 | $20.2K | 6,000,000 | 0.0% |
| Nuvalent Inc(NUVL) | Common | 670703107 | $18.4K | 1,102,671 | 0.0% |
| Tango Therapeutics Inc(TNGX) | Common | 87583X109 | $17.0K | 1,550,000 | 0.0% |
| Dice Therapeutics Inc | Common | 23345J104 | $14.2K | 562,500 | 0.0% |
| Avadel Pharmaceuticals PLC | Sponsored ADR | 05337M104 | $13.5K | 1,670,000 | 0.0% |
| Adverum Biotechnologies Inc(ADVMCHF) | Common | 00773U108 | $12.2K | 6,950,000 | 0.0% |
| IO Biotech Inc(IOBT) | Common | 449778109 | $10.2K | 2,055,883 | 0.0% |
| Genocea Biosciences Inc(GNCAQ) | Common | 372427401 | $5.9K | 5,084,184 | 0.0% |
| Fennec Pharmaceuticals Inc(FENC) | Common | 31447P100 | $5.3K | 1,200,000 | 0.0% |
| Sarepta Therapeutics Inc(SRPT)Call | Common | 803607100 | $2.9K | 300,000 | 0.0% |