Q1 2022 Holdings
Filed 2022-05-16 | 43 holdings | $1.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Argenx SE(ARGX) | Sponsored ADR | 04016X101 | $395.7M | 1,255,000 | 32.4% |
| Ascendis Pharma(ASND) | Sponsored ADR | 04351P101 | $258.2M | 2,200,000 | 21.1% |
| Biomarin Pharmaceutical Inc(BMRN) | Common | 09061G101 | $234.0M | 3,035,000 | 19.2% |
| Alnylam Pharmaceuticals Inc(ALNY) | Common | 02043Q107 | $212.3M | 1,300,000 | 17.4% |
| Acadia Pharmaceuticals Inc(ACAD) | Common | 004225108 | $55.1M | 2,275,000 | 4.5% |
| Aadi Biosciences Inc(WHWK) | Common | 00032Q104 | $31.0M | 1,829,402 | 2.5% |
| Biocryst Pharmaceuticlas Inc(BCRX) | Common | 09058V103 | $30.5M | 1,875,000 | 2.5% |
| Horizon Therapeutics PLC | Common | G46188101 | $683.9K | 6,500,000 | 0.1% |
| United Therapeutics Corp(UTHR) | Common | 91307C102 | $543.6K | 3,030,000 | 0.0% |
| Apellis Pharmaceuticals Inc(APLS) | Common | 03753U106 | $480.2K | 9,450,000 | 0.0% |
| Mirati Therapeutics Inc(MRTXEUR) | Common | 60468T105 | $437.8K | 5,325,000 | 0.0% |
| Spdr Series Trust - S&P Biotech(XBI) | ETF | 78464A870 | $274.1K | 3,050,000 | 0.0% |
| Sarepta Therapeutics Inc(SRPT) | Common | 803607100 | $244.9K | 3,135,000 | 0.0% |
| Amicus Therapeutics Inc(FOLD) | Common | 03152W109 | $194.1K | 20,500,000 | 0.0% |
| Seagen Inc(SGENUSD) | Common | 81181C104 | $189.4K | 1,315,000 | 0.0% |
| Xenon Pharmaceuticals Inc(XENE) | Common | 98420N105 | $152.4K | 4,985,000 | 0.0% |
| Iovance Biotherapeutics Inc(IOVA) | Common | 462260100 | $151.9K | 9,125,000 | 0.0% |
| Madrigal Pharmaceuticals Inc(MDGL) | Common | 558868105 | $139.8K | 1,425,000 | 0.0% |
| Iveric BIO Inc(OPHTEUR) | Common | 46583P102 | $122.0K | 7,250,000 | 0.0% |
| Kura Oncology Inc(KURA) | Common | 50127T109 | $77.2K | 4,800,000 | 0.0% |
| Krystal Biotech Inc(KRYS) | Common | 501147102 | $66.9K | 1,005,000 | 0.0% |
| Monte Rosa Therapeutics Inc(GLUE) | Common | 61225M102 | $46.4K | 3,311,434 | 0.0% |
| PMV Pharmaceuticals Inc(PMVP) | Common | 69353Y103 | $45.8K | 2,200,000 | 0.0% |
| Syndax Pharmaceuticals Inc(SNDX) | Common | 87164F105 | $38.6K | 2,220,500 | 0.0% |
| Design Therapeutics Inc(DSGN) | Common | 25056L103 | $35.9K | 2,222,222 | 0.0% |
| Kymera Therapeutics Inc(KYMR) | Common | 501575104 | $34.6K | 816,500 | 0.0% |
| Mannkind Corp(MNKD) | Common | 56400P706 | $32.4K | 8,800,000 | 0.0% |
| Cymabay Therapeutics Inc(CBAYUSD) | Common | 23257D103 | $32.0K | 10,300,000 | 0.0% |
| Marinus Pharmaceuticals Inc(MRNS*) | Common | 56854Q200 | $29.5K | 3,150,000 | 0.0% |
| Mersana Therapeutics Inc | Common | 59045L106 | $27.1K | 6,800,000 | 0.0% |
| Avidity Biosciences Inc(RNA) | Common | 05370A108 | $24.0K | 1,300,000 | 0.0% |
| Praxis Precision Medicines Inc | Common | 74006W108 | $22.0K | 2,150,000 | 0.0% |
| Dice Therapeutics Inc | Common | 23345J104 | $20.6K | 1,075,000 | 0.0% |
| Amarin Corp PLC | Sponsored ADR | 023111206 | $19.7K | 6,000,000 | 0.0% |
| Ultragenyx Pharmaceutical Inc(RARE) | Common | 90400D108 | $16.7K | 230,000 | 0.0% |
| Nuvalent Inc(NUVL) | Common | 670703107 | $14.6K | 1,049,471 | 0.0% |
| Tango Therapeutics Inc(TNGX) | Common | 87583X109 | $11.7K | 1,550,000 | 0.0% |
| Avadel Pharmaceuticals PLC | Sponsored ADR | 05337M104 | $11.4K | 1,670,000 | 0.0% |
| IO Biotech Inc(IOBT) | Common | 449778109 | $9.6K | 2,055,883 | 0.0% |
| Adverum Biotechnologies Inc(ADVMCHF) | Common | 00773U108 | $9.1K | 6,950,000 | 0.0% |
| Applied Molecular Trans Inc | Common | 03824M109 | $7.7K | 1,030,000 | 0.0% |
| Fennec Pharmaceuticals Inc(FENC) | Common | 31447P100 | $6.7K | 1,200,000 | 0.0% |
| Genocea Biosciences Inc(GNCAQ) | Common | 372427401 | $6.4K | 5,084,184 | 0.0% |