Q2 2022 Holdings
Filed 2022-08-15 | 117 holdings | $4.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $1.9B | 11,668,897 | 42.8% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $631.5M | 7,620,494 | 14.3% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $590.7M | 41,923,486 | 13.4% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $451.1M | 4,852,655 | 10.2% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $424.2M | 1,119,557 | 9.6% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $134.5M | 12,710,818 | 3.0% |
| AbCellera Biologics Inc.(ABCL) | COM | 00288U106 | $111.3M | 10,450,180 | 2.5% |
| Cerus Corporation(CERS) | COM | 157085101 | $85.0M | 16,067,558 | 1.9% |
| Biomea Fusion, Inc.(BMEA) | COM | 09077A106 | $25.2M | 2,104,559 | 0.6% |
| Altimmune, Inc.(ALT) | COM | 02155H200 | $24.3M | 2,075,403 | 0.5% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $16.7M | 9,830,877 | 0.4% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $15.4M | 827,480 | 0.3% |
| Seagen Inc.(SGENUSD) | COM | 81181C104 | $8.3M | 46,912,266 | 0.2% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.7M | 36,154,117 | 0.1% |
| Alector, Inc.(ALEC) | COM | 014442107 | $2.4M | 239,228 | 0.1% |
| aTyr Pharma, Inc.(ATYR) | COM | 002120202 | $1.1M | 374,395 | 0.0% |
| Cabaletta Bio, Inc.(CABA) | COM | 12674W109 | $702.0K | 662,063 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $132.3K | 17,310,490 | 0.0% |
| Global Blood Therapeutics, Inc. | COM | 37890U108 | $119.3K | 3,732,502 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $107.3K | 1,499,213 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $94.6K | 1,409,784 | 0.0% |
| Immunocore Holdings plc(IMCR) | ADS | 45258D105 | $94.0K | 2,520,730 | 0.0% |
| Horizon Therapeutics Public Ltd Co | SHS | G46188101 | $91.6K | 1,148,504 | 0.0% |
| Travere Therapeutics, Inc.(TVTX) | COM | 89422G107 | $80.0K | 3,300,009 | 0.0% |
| Replimune Group, Inc.(REPL) | COM | 76029N106 | $62.8K | 3,591,081 | 0.0% |
| Entrada Therapeutics, Inc.(TRDA) | COM | 29384C108 | $59.3K | 4,865,819 | 0.0% |
| IGM Biosciences, Inc.(1K0) | COM | 449585108 | $56.9K | 3,156,102 | 0.0% |
| Kymera Therapeutics, Inc.(KYMR) | COM | 501575104 | $56.7K | 2,879,825 | 0.0% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $53.0K | 807,735 | 0.0% |
| Prelude Therapeutics Inc.(PRLD) | COM | 74065P101 | $52.8K | 10,123,824 | 0.0% |
| Nurix Therapeutics, Inc.(NRIX) | COM | 67080M103 | $49.2K | 3,882,125 | 0.0% |
| Legend Biotech Corporation(LEGN) | SPONSORED ADS | 52490G102 | $47.1K | 856,658 | 0.0% |
| Alkermes plc(ALKS) | SHS | G01767105 | $44.7K | 1,500,000 | 0.0% |
| ChemoCentryx, Inc.(CCXIEUR) | COM | 16383L106 | $44.4K | 1,792,657 | 0.0% |
| Chinook Therapeutics, Inc.(290A) | COM | 16961L106 | $44.3K | 2,534,102 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $42.5K | 2,156,001 | 0.0% |
| Immatics N.V.(IMTX) | SHS | N44445109 | $38.5K | 4,423,731 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $37.3K | 14,614,264 | 0.0% |
| Sarepta Therapeutics, Inc. | DBCV 1.5% 11/15/2024 | 803607AB6 | $36.6K | $29,174,000 | 0.0% |
| Insmed Incorporated | Note 0.75% 6/1/2028 | 457669AB5 | $33.3K | $40,000,000 | 0.0% |
| Aerovate Therapeutics, Inc. | COM | 008064107 | $32.4K | 2,070,010 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $31.5K | 21,169,805 | 0.0% |
| Verastem, Inc. | COM | 92337C104 | $31.3K | 26,988,898 | 0.0% |
| Ultragenyx Pharmaceutical Inc.(RARE) | COM | 90400D108 | $28.1K | 470,974 | 0.0% |
| 2seventy bio, Inc.(TSVT*) | COMMON STOCK | 901384107 | $27.2K | 2,062,744 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $27.1K | 2,799,577 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $24.1K | 9,873,488 | 0.0% |
| Pacific Biosciences of California, Inc.(PACB) | COM | 69404D108 | $24.1K | 5,444,963 | 0.0% |
| Xenon Pharmaceuticals Inc.(XENE) | COM | 98420N105 | $22.9K | 751,639 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $22.7K | 8,131,678 | 0.0% |