Q3 2022 Holdings
Filed 2022-11-14 | 115 holdings | $3.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $1.6B | 11,668,897 | 39.9% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $685.9M | 41,923,486 | 17.4% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $646.0M | 7,620,494 | 16.4% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $501.1M | 4,852,655 | 12.7% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $160.2M | 12,710,818 | 4.1% |
| AbCellera Biologics Inc.(ABCL) | COM | 00288U106 | $103.4M | 10,450,180 | 2.6% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $98.9M | 280,159 | 2.5% |
| Cerus Corporation(CERS) | COM | 157085101 | $57.8M | 16,067,558 | 1.5% |
| Altimmune, Inc.(ALT) | COM | 02155H200 | $22.6M | 1,769,681 | 0.6% |
| Biomea Fusion, Inc.(BMEA) | COM | 09077A106 | $20.6M | 2,104,559 | 0.5% |
| Bicycle Therapeutics plc(BCYC) | SPONSORED ADS | 088786108 | $19.6M | 843,814 | 0.5% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $14.4M | 735,716 | 0.4% |
| Aadi Bioscience, Inc.(WHWK) | COM | 00032Q104 | $14.0M | 989,928 | 0.4% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $10.6M | 9,830,877 | 0.3% |
| Seagen Inc.(SGENUSD) | COM | 81181C104 | $6.4M | 46,912,266 | 0.2% |
| Century Therapeutics, Inc.(IPSC) | COM | 15673T100 | $3.7M | 370,587 | 0.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.4M | 36,154,574 | 0.1% |
| Alector, Inc.(ALEC) | COM | 014442107 | $2.3M | 239,228 | 0.1% |
| aTyr Pharma, Inc.(ATYR) | COM | 002120202 | $604.0K | 201,361 | 0.0% |
| Cabaletta Bio, Inc.(CABA) | COM | 12674W109 | $430.0K | 662,063 | 0.0% |
| Global Blood Therapeutics, Inc. | COM | 37890U108 | $254.2K | 3,732,502 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $148.5K | 6,062,702 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $134.0K | 17,310,490 | 0.0% |
| Immunocore Holdings plc(IMCR) | ADS | 45258D105 | $118.3K | 2,520,731 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $98.5K | 1,409,784 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $97.4K | 1,499,213 | 0.0% |
| ChemoCentryx, Inc.(CCXIEUR) | COM | 16383L106 | $92.6K | 1,792,657 | 0.0% |
| Travere Therapeutics, Inc.(TVTX) | COM | 89422G107 | $81.3K | 3,300,009 | 0.0% |
| Akero Therapeutics, Inc.(AKRO) | COM | 00973Y108 | $80.6K | 2,368,378 | 0.0% |
| Entrada Therapeutics, Inc.(TRDA) | COM | 29384C108 | $76.7K | 4,865,819 | 0.0% |
| IGM Biosciences, Inc.(1K0) | COM | 449585108 | $71.8K | 3,156,102 | 0.0% |
| Replimune Group, Inc.(REPL) | COM | 76029N106 | $67.2K | 3,893,843 | 0.0% |
| Prelude Therapeutics Inc.(PRLD) | COM | 74065P101 | $66.9K | 10,123,824 | 0.0% |
| Kymera Therapeutics, Inc.(KYMR) | COM | 501575104 | $62.7K | 2,879,825 | 0.0% |
| Horizon Therapeutics Public Ltd Co | SHS | G46188101 | $60.0K | 969,727 | 0.0% |
| Nurix Therapeutics, Inc.(NRIX) | COM | 67080M103 | $50.6K | 3,882,125 | 0.0% |
| Chinook Therapeutics, Inc.(290A) | COM | 16961L106 | $49.8K | 2,534,102 | 0.0% |
| Verve Therapeutics, Inc. | COM | 92539P101 | $48.7K | 1,416,530 | 0.0% |
| Immatics N.V.(IMTX) | SHS | N44445109 | $44.2K | 4,423,731 | 0.0% |
| Forma Therapeutics Holdings, Inc. | SHS | 34633R104 | $37.6K | 1,886,760 | 0.0% |
| Insmed Incorporated | Note 0.75% 6/1/2028 | 457669AB5 | $36.3K | $40,000,000 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $35.9K | 2,799,577 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $34.3K | 8,131,678 | 0.0% |
| Aerovate Therapeutics, Inc. | COM | 008064107 | $32.8K | 1,979,568 | 0.0% |
| 2seventy bio, Inc.(TSVT*) | COM | 901384107 | $30.0K | 2,062,744 | 0.0% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $29.4K | 422,185 | 0.0% |
| Xenon Pharmaceuticals Inc.(XENE) | COM | 98420N105 | $27.1K | 751,639 | 0.0% |
| CinCor Pharma, Inc. | COM | 17240Y109 | $26.5K | 807,212 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $25.9K | 14,614,264 | 0.0% |
| Ideaya Biosciences, Inc.(IDYA) | COM | 45166A102 | $24.9K | 1,668,355 | 0.0% |