Q4 2022 Holdings
Filed 2023-02-14 | 53 holdings | $1.7B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Karuna Therapeutics Inc | COM | 48576A100 | $407.4M | 2,073,124 | 24.2% |
| Natera Inc(NTRA) | COM | 632307104 | $124.5M | 3,100,560 | 7.4% |
| Aerovate Therapeutics Inc | COM | 008064107 | $110.1M | 3,758,686 | 6.5% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $107.6M | 880,800 | 6.4% |
| Sanofi SA(SNY) | SPONSORED ADR | 80105N105 | $95.2M | 1,965,475 | 5.6% |
| Cincor Pharma Inc | COM | 17240Y109 | $74.6M | 6,073,949 | 4.4% |
| Merck & Co Inc(MRK) | COM | 58933Y105 | $66.9M | 603,356 | 4.0% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $61.6M | 3,181,442 | 3.7% |
| Horizon Therapeutics PLC | SHS | G46188101 | $47.0M | 413,173 | 2.8% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $45.3M | 156,989 | 2.7% |
| AstraZeneca PLC(AZN) | SPONSORED ADR | 046353108 | $41.6M | 613,673 | 2.5% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $40.8M | 394,643 | 2.4% |
| Reata Pharmaceuticals Inc(RETAEUR) | CL A | 75615P103 | $37.7M | 992,029 | 2.2% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $32.1M | 247,955 | 1.9% |
| CTI Biopharma Corp(CTIC1USD) | COM | 12648L601 | $27.7M | 4,606,527 | 1.6% |
| Inhibrx Inc(INBXUSD) | COM | 45720L107 | $27.4M | 1,110,183 | 1.6% |
| United Therapeutics Corp(UTHR) | COM | 91307C102 | $24.8M | 89,207 | 1.5% |
| Alnylam Pharmaceuticals Inc(ALNY)Call | COM | 02043Q107 | $23.8M | 100,000 | 1.4% |
| Cytokinetics Inc(CYTK) | COM | 23282W605 | $23.3M | 508,930 | 1.4% |
| Chinook Therapeutics Inc(290A) | COM | 16961L106 | $21.1M | 806,459 | 1.3% |
| Zentalis Pharmaceuticals Inc(ZNTL) | COM | 98943L107 | $20.2M | 1,004,045 | 1.2% |
| Prometheus Biosciences Inc | COM | 74349U108 | $19.4M | 176,545 | 1.2% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $17.9M | 703,074 | 1.1% |
| Align Technology Inc(ALGN) | COM | 016255101 | $17.5M | 83,100 | 1.0% |
| Immatics NV(IMTX) | SHS | N44445109 | $17.4M | 2,000,776 | 1.0% |
| Dexcom Inc(DXCM) | COM | 252131107 | $15.9M | 140,678 | 0.9% |
| Iveric Bio Inc(OPHTEUR) | COM | 46583P102 | $13.7M | 638,398 | 0.8% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $13.4M | 56,448 | 0.8% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $12.2M | 578,268 | 0.7% |
| Y-mAbs Therapeutics Inc(YMABUSD) | COM | 984241109 | $10.7M | 2,194,278 | 0.6% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $8.6M | 474,530 | 0.5% |
| ImmunoGen Inc(IMGNEUR) | COM | 45253H101 | $8.4M | 1,686,154 | 0.5% |
| Kura Oncology Inc(KURA) | COM | 50127T109 | $7.4M | 593,561 | 0.4% |
| Agenus Inc(AGENEUR) | COM | 00847G705 | $6.9M | 2,894,057 | 0.4% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $6.5M | 314,811 | 0.4% |
| Geron Corp(GERN)Call | COM | 374163103 | $5.7M | 2,369,100 | 0.3% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $4.6M | 631,411 | 0.3% |
| Galera Therapeutics Inc(GRTX) | COM | 36338D108 | $4.6M | 3,083,712 | 0.3% |
| Cytokinetics Inc(CYTK)Call | COM | 23282W605 | $4.6M | 100,000 | 0.3% |
| Inozyme Pharma Inc | COM | 45790W108 | $3.8M | 3,655,308 | 0.2% |
| Nextcure Inc | COM | 65343E108 | $3.8M | 2,671,856 | 0.2% |
| Nucana PLC | SPONSORED ADR | 67022C106 | $3.7M | 5,599,999 | 0.2% |
| Bolt Biotherapeutics Inc(BOLT1EUR) | COM | 097702104 | $3.6M | 2,754,437 | 0.2% |
| Geron Corp(GERN) | COM | 374163103 | $3.5M | 1,459,589 | 0.2% |
| Agenus Inc(AGENEUR)Call | COM | 00847G705 | $3.0M | 1,267,000 | 0.2% |
| CTI Biopharma Corp(CTIC1USD)Call | COM | 12648L601 | $2.5M | 410,000 | 0.1% |
| PDS Biotechnology Corp(PDSB) | COM | 70465T107 | $1.9M | 142,635 | 0.1% |
| Nucana PLC | COMMON SHARES | GB00BYWYV | $1.6M | 2,400,000 | 0.1% |
| ObsEva SA | COM | H5861P103 | $688.7K | 4,749,623 | 0.0% |
| Synlogic Inc | COM | 87166L100 | $437.0K | 574,972 | 0.0% |