Q4 2022 Holdings
Filed 2023-02-14 | 69 holdings | $2.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $247.2M | 20,249,789 | 10.1% |
| Krystal Biotech Inc(KRYS) | COM | 501147102 | $150.3M | 1,896,645 | 6.1% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $144.3M | 2,632,912 | 5.9% |
| Replimune Group Inc(REPL) | COM | 76029N106 | $131.4M | 4,831,709 | 5.4% |
| Fate Therapeutics Inc(FATE) | COM | 31189P102 | $130.7M | 12,957,222 | 5.3% |
| Iveric BIO Inc(OPHTEUR) | COM | 46583P102 | $96.4M | 4,502,111 | 3.9% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $93.1M | 2,360,414 | 3.8% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $88.1M | 1,977,451 | 3.6% |
| Pliant Therapeutics Inc(PLRX) | COM | 729139105 | $75.0M | 3,878,599 | 3.1% |
| Beam Therapeutics Inc(BEAM) | COM | 07373V105 | $69.2M | 1,770,587 | 2.8% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $66.7M | 2,673,837 | 2.7% |
| Livanova PLC(LIVN) | SHS | G5509L101 | $61.4M | 1,106,409 | 2.5% |
| Deciphera Pharmaceuticals in(DCPHEUR) | COM | 24344T101 | $58.9M | 3,593,317 | 2.4% |
| IGM Biosciences Inc(1K0) | COM | 449585108 | $56.7M | 3,334,355 | 2.3% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $56.3M | 148,517 | 2.3% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $50.8M | 318,945 | 2.1% |
| Penumbra Inc(PEN) | COM | 70975L107 | $49.3M | 221,809 | 2.0% |
| Zymeworks del Inc(ZYME) | COM | 98985Y108 | $48.5M | 6,175,918 | 2.0% |
| Regenxbio Inc(RGNX) | COM | 75901B107 | $43.4M | 1,913,512 | 1.8% |
| Immunogen Inc(IMGNEUR) | COM | 45253H101 | $42.3M | 8,532,817 | 1.7% |
| Prime Medicine Inc(PRME) | COM | 74168J101 | $41.0M | 2,209,350 | 1.7% |
| Repare Therapeutics Inc(RPTX) | COM | 760273102 | $39.5M | 2,684,396 | 1.6% |
| 1Life Healthcare Inc | COM | 68269G107 | $38.9M | 2,326,625 | 1.6% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $32.9M | 3,000,784 | 1.3% |
| OAK STR Health Inc(OSH3EUR) | COM | 67181A107 | $30.6M | 1,420,617 | 1.3% |
| Ventyx Biosciences Inc(VTYX) | COM | 92332V107 | $29.3M | 894,974 | 1.2% |
| ADC Therapeutics SA(ADCT) | SHS | H0036K147 | $29.1M | 7,590,849 | 1.2% |
| Stryker Corporation(SYK) | COM | 863667101 | $25.9M | 105,880 | 1.1% |
| Entrada Therapeutics Inc(TRDA) | COM | 29384C108 | $25.1M | 1,854,108 | 1.0% |
| Gritstone BIO Inc(2JQ) | COM | 39868T105 | $23.9M | 6,931,460 | 1.0% |
| Verve Therapeutics Inc | COM | 92539P101 | $23.6M | 1,221,903 | 1.0% |
| Centene Corp del(CNC) | COM | 15135B101 | $23.1M | 281,260 | 0.9% |
| Augmedix Inc(AUGX) | COM | 05105P107 | $22.4M | 14,380,327 | 0.9% |
| Allakos Inc(ALLKGUSD) | COM | 01671P100 | $21.4M | 2,545,275 | 0.9% |
| Atara Biotherapeutics Inc(ATRAGBX) | COM | 046513107 | $20.5M | 6,242,756 | 0.8% |
| Elevance Health Inc(ELV) | COM | 036752103 | $20.0M | 38,970 | 0.8% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $19.3M | 1,088,131 | 0.8% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $19.0M | 2,095,820 | 0.8% |
| Annexon Inc(ANNX) | COM | 03589W102 | $18.1M | 3,503,190 | 0.7% |
| Stevanato Group S P A(STVN) | ORD SHS | T9224W109 | $16.9M | 942,525 | 0.7% |
| Absci Corporation(ABSI) | COM | 00091E109 | $16.9M | 8,031,094 | 0.7% |
| Rapt Therapeutics Inc(RAPTEUR) | COM | 75382E109 | $15.5M | 784,832 | 0.6% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $14.9M | 625,000 | 0.6% |
| Shattuck Labs Inc(STTK) | COM | 82024L103 | $12.9M | 5,619,914 | 0.5% |
| Medavail Holdings Inc | COM | 58406B103 | $10.4M | 34,604,516 | 0.4% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $10.1M | 266,187 | 0.4% |
| Lava Therapeutics NV | SHS | N51517105 | $9.9M | 2,816,196 | 0.4% |
| Allovir Inc | COM | 019818103 | $9.8M | 1,907,969 | 0.4% |
| Science 37 Holdings Inc | COM | 808644108 | $8.2M | 19,808,234 | 0.3% |
| ALX Oncology Hldgs Inc(ALXO) | COM | 00166B105 | $6.8M | 607,470 | 0.3% |