Q1 2023 Holdings
Filed 2023-05-11 | 53 holdings | $1.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Karuna Therapeutics Inc | COM | 48576A100 | $322.1M | 1,773,124 | 20.6% |
| Natera Inc(NTRA) | COM | 632307104 | $172.1M | 3,100,560 | 11.0% |
| Merck & Co Inc(MRK) | COM | 58933Y105 | $89.5M | 841,522 | 5.7% |
| Spdr S&P 500 ETF Trust(SPY)Put | TR UNIT | 78462F103 | $81.9M | 200,000 | 5.2% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $80.8M | 754,032 | 5.2% |
| Aerovate Therapeutics Inc | COM | 008064107 | $75.8M | 3,758,686 | 4.8% |
| Reata Pharmaceuticals Inc(RETAEUR) | CL A | 75615P103 | $57.1M | 627,683 | 3.6% |
| Eli Lilly and Co(LLY) | COM | 532457108 | $47.1M | 137,100 | 3.0% |
| Horizon Therapeutics PLC | SHS | G46188101 | $44.6M | 408,819 | 2.9% |
| Intuitive Surgical Inc(ISRG) | COM | 46120E602 | $38.2M | 149,589 | 2.4% |
| Biogen Inc(BIIB) | COM | 09062X103 | $36.9M | 132,600 | 2.4% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $34.9M | 359,035 | 2.2% |
| Dexcom Inc(DXCM) | COM | 252131107 | $29.9M | 257,227 | 1.9% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $28.4M | 1,263,721 | 1.8% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $26.9M | 3,467,156 | 1.7% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $25.0M | 517,095 | 1.6% |
| Zentalis Pharmaceuticals Inc(ZNTL) | COM | 98943L107 | $24.8M | 1,439,062 | 1.6% |
| Inhibrx Inc(INBXUSD) | COM | 45720L107 | $23.5M | 1,244,488 | 1.5% |
| Chinook Therapeutics Inc(290A) | COM | 16961L106 | $23.2M | 1,002,348 | 1.5% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $22.7M | 1,075,424 | 1.5% |
| Iveric bio Inc(OPHTEUR) | COM | 46583P102 | $22.0M | 905,982 | 1.4% |
| Immatics NV(IMTX) | SHS | N44445109 | $21.6M | 3,132,694 | 1.4% |
| Inozyme Pharma Inc | COM | 45790W108 | $20.9M | 3,655,308 | 1.3% |
| Geron Corp(GERN) | COM | 374163103 | $18.0M | 8,274,892 | 1.1% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $16.4M | 119,065 | 1.0% |
| Exelixis Inc(EXEL) | COM | 30161Q104 | $16.1M | 831,243 | 1.0% |
| Vir Biotechnology Inc(VIR) | COM | 92764N102 | $15.3M | 657,559 | 1.0% |
| Celldex Therapeutics Inc(CLDX) | COM | 15117B202 | $15.1M | 419,397 | 1.0% |
| Prometheus Biosciences Inc | COM | 74349U108 | $13.3M | 123,842 | 0.8% |
| Cytokinetics Inc(CYTK) | COM | 23282W605 | $12.5M | 353,796 | 0.8% |
| CTI Biopharma Corp(CTIC1USD) | COM | 12648L601 | $11.7M | 2,794,542 | 0.8% |
| Y-mAbs Therapeutics Inc(YMABUSD) | COM | 984241109 | $11.0M | 2,194,278 | 0.7% |
| Agenus Inc(AGENEUR) | COM | 00847G705 | $9.7M | 6,407,457 | 0.6% |
| Marinus Pharmaceuticals Inc(MRNS*) | COM | 56854Q200 | $8.3M | 1,200,389 | 0.5% |
| Galera Therapeutics Inc(GRTX) | COM | 36338D108 | $7.9M | 3,083,712 | 0.5% |
| Kura Oncology Inc(KURA) | COM | 50127T109 | $7.5M | 616,169 | 0.5% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $7.5M | 120,896 | 0.5% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $6.2M | 453,149 | 0.4% |
| Nucana PLC | SPONSORED ADR | 67022C106 | $5.4M | 5,599,999 | 0.3% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $4.0M | 183,838 | 0.3% |
| Nextcure Inc | COM | 65343E108 | $4.0M | 2,671,856 | 0.3% |
| ImmunoGen Inc(IMGNEUR)Call | COM | 45253H101 | $3.8M | 1,000,000 | 0.2% |
| Bolt Biotherapeutics Inc(BOLT1EUR) | COM | 097702104 | $3.8M | 2,754,437 | 0.2% |
| ImmunoGen Inc(IMGNEUR) | COM | 45253H101 | $3.6M | 924,532 | 0.2% |
| Keros Therapeutics Inc(KROS) | COM | 492327101 | $3.3M | 77,100 | 0.2% |
| Novocure Ltd(NVCR)Call | ORD SHS | G6674U108 | $3.0M | 50,000 | 0.2% |
| Nucana PLC | COMMON SHARES | GB00BYWYV | $2.3M | 2,400,000 | 0.1% |
| bluebird bio Inc | COM | 09609G100 | $2.1M | 672,815 | 0.1% |
| PDS Biotechnology Corp(PDSB) | COM | 70465T107 | $877.2K | 142,635 | 0.1% |
| Fusion Pharmaceuticals Inc | COM | 36118A100 | $441.5K | 117,099 | 0.0% |