Q3 2023 Holdings
Filed 2023-11-14 | 101 holdings | $17.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Seagen Inc.(SGENUSD) | COM | 81181C104 | $9.5B | 44,554,162 | 54.5% |
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $2.1B | 11,668,897 | 12.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.1B | 36,178,566 | 12.0% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $893.3M | 42,864,612 | 5.1% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $337.1M | 3,810,248 | 1.9% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $225.6M | 1,545,113 | 1.3% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $153.7M | 6,702,349 | 0.9% |
| Roivant Sciences Ltd.(ROIV) | SHS | G76279101 | $138.7M | 11,877,171 | 0.8% |
| Immunocore Holdings plc(IMCR) | ADS | 45258D105 | $130.8M | 2,520,731 | 0.8% |
| Invitae Corporation | Note 1.5% 4/1/2028 | 46185LAD5 | $130.4M | $300,000,000 | 0.8% |
| Akero Therapeutics, Inc.(AKRO) | COM | 00973Y108 | $119.8M | 2,368,378 | 0.7% |
| AbCellera Biologics Inc.(ABCL) | COM | 00288U106 | $95.5M | 20,763,323 | 0.6% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $90.0M | 12,710,818 | 0.5% |
| Replimune Group, Inc.(REPL) | COM | 76029N106 | $78.3M | 4,578,280 | 0.5% |
| Entrada Therapeutics, Inc.(TRDA) | COM | 29384C108 | $76.9M | 4,865,819 | 0.4% |
| Revolution Medicines, Inc.(RVMD) | COM | 76155X100 | $74.5M | 2,691,493 | 0.4% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $74.3M | 151,215 | 0.4% |
| SpringWorks Therapeutics, Inc. | COM | 85205L107 | $69.4M | 2,999,846 | 0.4% |
| Kymera Therapeutics, Inc.(KYMR) | COM | 501575104 | $66.0M | 4,750,400 | 0.4% |
| Immatics N.V.(IMTX) | SHS | N44445109 | $65.3M | 5,640,816 | 0.4% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $61.4M | 1,409,784 | 0.4% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $48.8M | 2,809,577 | 0.3% |
| Ultragenyx Pharmaceutical Inc.(RARE) | COM | 90400D108 | $48.7M | 1,366,547 | 0.3% |
| Denali Therapeutics Inc.(DNLI) | COM | 24823R105 | $47.3M | 2,292,003 | 0.3% |
| Prelude Therapeutics Inc.(PRLD) | COM | 74065P101 | $31.3M | 10,123,824 | 0.2% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $31.2M | 17,310,490 | 0.2% |
| Nurix Therapeutics, Inc.(NRIX) | COM | 67080M103 | $30.5M | 3,882,125 | 0.2% |
| Biomea Fusion, Inc.(BMEA) | COM | 09077A106 | $29.0M | 2,108,949 | 0.2% |
| Ideaya Biosciences, Inc.(IDYA) | COM | 45166A102 | $28.7M | 1,062,123 | 0.2% |
| Cerus Corporation(CERS) | COM | 157085101 | $27.9M | 17,239,501 | 0.2% |
| Aerovate Therapeutics, Inc. | COM | 008064107 | $26.6M | 1,963,479 | 0.2% |
| IGM Biosciences, Inc.(1K0) | COM | 449585108 | $26.4M | 3,157,764 | 0.2% |
| Xenon Pharmaceuticals Inc.(XENE) | COM | 98420N105 | $25.7M | 751,639 | 0.1% |
| Cabaletta Bio, Inc.(CABA) | COM | 12674W109 | $24.3M | 1,594,000 | 0.1% |
| Monte Rosa Therapeutics, Inc.(GLUE) | COM | 61225M102 | $23.5M | 4,916,095 | 0.1% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $19.9M | 14,614,264 | 0.1% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $19.7M | 169,934 | 0.1% |
| Verve Therapeutics, Inc. | COM | 92539P101 | $18.8M | 1,416,530 | 0.1% |
| Bicycle Therapeutics plc(BCYC) | SPONSORED ADS | 088786108 | $17.0M | 843,814 | 0.1% |
| Immunovant, Inc.(IMVT) | COM | 45258J102 | $16.3M | 425,009 | 0.1% |
| Cogent Biosciences, Inc.(COGT) | COM | 19240Q201 | $12.6M | 1,292,966 | 0.1% |
| Day One Biopharmaceuticals, Inc.(DAWN) | COM | 23954D109 | $12.3M | 1,000,000 | 0.1% |
| Prime Medicine, Inc.(PRME) | COM | 74168J101 | $9.8M | 1,028,466 | 0.1% |
| 2seventy bio, Inc.(TSVT*) | COM | 901384107 | $9.8M | 2,497,526 | 0.1% |
| Relay Therapeutics, Inc.(RLAY) | COM | 75943R102 | $9.8M | 1,160,117 | 0.1% |
| Pacific Biosciences of California, Inc.(PACB) | COM | 69404D108 | $9.4M | 1,127,782 | 0.1% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $8.7M | 343,000 | 0.0% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $8.6M | 10,969,282 | 0.0% |
| Tango Therapeutics, Inc.(TNGX) | COM | 87583X109 | $8.4M | 750,000 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $8.4M | 8,131,678 | 0.0% |