Q4 2023 Holdings
Filed 2024-02-14 | 62 holdings | $6.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Ascendis Pharma A/S(ASND) | SH | 04351P101 | $1.3B | 10,107,400 | 19.9% |
| Immunogen Inc(IMGNEUR) | SH | 45253H101 | $704.2M | 23,750,601 | 11.0% |
| Vaxcyte Inc(PCVX) | SH | 92243G108 | $495.6M | 7,891,254 | 7.7% |
| Legend Biotech Corp(LEGN) | SH | 52490G102 | $376.9M | 6,264,707 | 5.9% |
| Rhythm Pharmaceuticals Inc(RYTM) | SH | 76243J105 | $245.0M | 5,330,412 | 3.8% |
| Aerovate Therapeutics Inc | SH | 008064107 | $187.0M | 8,263,982 | 2.9% |
| Inhibrx Inc(INBXUSD) | SH | 45720L107 | $179.5M | 4,724,207 | 2.8% |
| Cymabay Therapeutics Inc(CBAYUSD) | SH | 23257D103 | $163.9M | 6,940,000 | 2.6% |
| Biogen Inc(BIIB) | SH | 09062X103 | $137.9M | 532,892 | 2.2% |
| Rxsight Inc(RXST) | SH | 78349D107 | $137.3M | 3,404,285 | 2.1% |
| 89Bio Inc(ETNBGBP) | SH | 282559103 | $127.5M | 11,416,948 | 2.0% |
| Verona Pharma PLC(VRNA) | SH | 925050106 | $125.6M | 6,317,990 | 2.0% |
| DAY One Biopharmaceuticals I(DAWN) | SH | 23954D109 | $114.0M | 7,809,852 | 1.8% |
| An2 Therapeutics Inc(ANTX) | SH | 037326105 | $113.7M | 5,551,295 | 1.8% |
| Tyra Biosciences Inc(TYRA) | SH | 90240B106 | $100.2M | 7,236,454 | 1.6% |
| Janux Therapeutics Inc(JANX) | SH | 47103J105 | $98.3M | 9,165,652 | 1.5% |
| Geron Corp(GERN) | SH | 374163103 | $97.5M | 46,202,425 | 1.5% |
| Icosavax Inc | SH | 45114M109 | $94.0M | 5,963,565 | 1.5% |
| Alpine Immune Sciences Inc(NVLSEUR) | SH | 02083G100 | $93.6M | 4,909,763 | 1.5% |
| Wave Life Sciences LTD(WVE) | SH | Y95308105 | $91.9M | 18,202,009 | 1.4% |
| Newamsterdam Pharma Co NV(NAMS) | SH | N62509109 | $87.8M | 7,864,000 | 1.4% |
| 4D Molecular Therapeutics in(FDMT) | SH | 35104E100 | $84.3M | 4,163,211 | 1.3% |
| Evolent Health Inc(EVH) | SH | 30050B101 | $84.2M | 2,549,132 | 1.3% |
| Axsome Therapeutics Inc(AXSM) | SH | 05464T104 | $79.6M | 1,000,000 | 1.2% |
| Fulcrum Therapeutics Inc(FULC) | SH | 359616109 | $78.4M | 11,609,704 | 1.2% |
| Cytek Biosciences Inc(CTKB) | SH | 23285D109 | $62.1M | 6,809,404 | 1.0% |
| Acumen Pharmaceuticals Inc(ABOS) | SH | 00509G209 | $57.3M | 14,932,063 | 0.9% |
| Pepgen Inc(PEPG) | SH | 713317105 | $55.3M | 8,131,952 | 0.9% |
| Apogee Therapeutics Inc(APGE) | SH | 03770N101 | $55.3M | 1,977,901 | 0.9% |
| ARS Pharmaceuticals Inc(SPRY) | SH | 82835W108 | $51.8M | 9,459,678 | 0.8% |
| Nkarta Inc(NKTX) | SH | 65487U108 | $51.5M | 7,805,129 | 0.8% |
| VOR Biopharma Inc | SH | 929033108 | $51.2M | 22,748,880 | 0.8% |
| Iteos Therapeutics Inc(5E7) | SH | 46565G104 | $48.4M | 4,417,259 | 0.8% |
| Madrigal Pharmaceuticals Inc(MDGL) | SH | 558868105 | $47.3M | 204,500 | 0.7% |
| Urogen Pharma LTD(URGN) | SH | M96088105 | $46.3M | 3,083,430 | 0.7% |
| Macrogenics Inc(MGNX) | SH | 556099109 | $39.0M | 4,053,077 | 0.6% |
| Eliem Therapeutics Inc(CLYM) | SH | 28658R106 | $35.5M | 13,150,849 | 0.6% |
| Taysha Gene Therapies Inc(TSHA) | SH | 877619106 | $32.7M | 18,472,503 | 0.5% |
| GH Research PLC(GHRS) | SH | G3855L106 | $32.4M | 5,587,333 | 0.5% |
| Enliven Therapeutics Inc(ELVN) | SH | 29337E102 | $29.4M | 2,122,465 | 0.5% |
| C4 Therapeutics Inc(CCCC) | SH | 12529R107 | $27.6M | 4,878,000 | 0.4% |
| Mineralys Therapeutics Inc(MLYS) | SH | 603170101 | $27.3M | 3,178,476 | 0.4% |
| Werewolf Therapeutics Inc(HOWL) | SH | 95075A107 | $23.7M | 6,144,881 | 0.4% |
| Acrivon Therapeutics Inc(ACRV) | SH | 004890109 | $23.7M | 4,810,508 | 0.4% |
| Pliant Therapeutics Inc(PLRX) | SH | 729139105 | $23.2M | 1,281,000 | 0.4% |
| Third Harmonic BIO Inc(THRD) | SH | 88427A107 | $22.3M | 2,033,056 | 0.3% |
| Avidity Biosciences Inc(RNA) | SH | 05370A108 | $22.2M | 2,454,533 | 0.3% |
| Solid Biosciences Inc(SLDB) | SH | 83422E204 | $21.0M | 3,426,286 | 0.3% |
| Structure Therapeutics Inc(GPCR) | SH | 86366E106 | $19.8M | 486,832 | 0.3% |
| Tenaya Therapeutics Inc(TNYA) | SH | 87990A106 | $17.8M | 5,507,347 | 0.3% |