Q4 2016 Holdings
Filed 2017-02-14 | 133 holdings | $1.5B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $744.6M | 25,819,768 | 48.5% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $398.2M | 4,806,483 | 26.0% |
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $111.5M | 3,673,175 | 7.3% |
| AbbVie Inc.(ABBV) | COM | 00287Y109 | $105.6M | 1,685,994 | 6.9% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $69.4M | 10,963,944 | 4.5% |
| Cerus Corporation(CERS) | COM | 157085101 | $56.8M | 13,053,275 | 3.7% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $20.7M | 1,023,266 | 1.4% |
| Agios Pharmaceuticals, Inc.(AGIO) | COM | 00847X104 | $5.4M | 128,666 | 0.4% |
| Catalyst Pharmaceuticals, Inc.(CPRX) | COM | 14888U101 | $5.4M | 5,102,153 | 0.3% |
| Biogen Inc.(BIIB) | COM | 09062X103 | $4.7M | 16,500 | 0.3% |
| Seattle Genetics, Inc. | COM | 812578102 | $2.4M | 45,711,856 | 0.2% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.4M | 23,499,087 | 0.2% |
| Cellectis S.A.(CLLS) | SPONSORED ADS | 15117K103 | $848.0K | 50,000 | 0.1% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $800.6K | 6,543,295 | 0.1% |
| Aldeyra Therapeutics, Inc.(ALDX) | COM | 01438T106 | $760.0K | 142,000 | 0.0% |
| Incyte Corporation | NOTE 1.25% 11/15/2020 | 45337CAL6 | $558.7K | $274,500,000 | 0.0% |
| Incyte Corporation | NOTE 0.375% 11/15/2018 | 45337CAK8 | $518.1K | $259,000,000 | 0.0% |
| Arbutus Biopharma Corporation(ABUS) | COM | 03879J100 | $442.0K | 180,582 | 0.0% |
| Alnylam Pharmaceuticals, Inc.(ALNY) | COM | 02043Q107 | $425.0K | 11,340 | 0.0% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $405.0K | 100,000 | 0.0% |
| Genomic Health, Inc.(GHDX) | COM | 37244C101 | $404.7K | 13,770,302 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $193.6K | 5,509,560 | 0.0% |
| Aquinox Pharmaceuticals, Inc. | COM | 03842B101 | $174.0K | 10,536,092 | 0.0% |
| BioMarin Pharmaceutical Inc. | NOTE 1.875% 4/23/2017 | 09061GAD3 | $90.5K | $22,379,000 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR NEW | 023111206 | $68.3K | 22,169,509 | 0.0% |
| Bellicum Pharmaceuticals, Inc. | COM | 079481107 | $66.3K | 4,865,647 | 0.0% |
| Spark Therapeutics, Inc. | COM | 84652J103 | $65.8K | 1,318,341 | 0.0% |
| Acorda Therapeutics, Inc. | COM | 00484M106 | $62.1K | 3,301,791 | 0.0% |
| Achaogen, Inc. | COM | 004449104 | $59.7K | 4,582,382 | 0.0% |
| Advanced Accelerator Applications S.A. | SPONSORED ADR | 00790T100 | $58.0K | 2,167,137 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $57.9K | 7,288,300 | 0.0% |
| Exelixis, Inc.(EXEL) | COM | 30161Q104 | $44.8K | 3,003,569 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $34.7K | 895,422 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $31.2K | 2,383,569 | 0.0% |
| Versartis, Inc. | COM | 92529L102 | $28.6K | 1,920,845 | 0.0% |
| Foamix Pharmaceuticals Ltd. | SHS | M46135105 | $27.4K | 2,466,702 | 0.0% |
| Progenics Pharmaceuticals, Inc. | COM | 743187106 | $27.2K | 3,150,808 | 0.0% |
| Acorda Therapeutics, Inc. | NOTE 1.75% 6/15/2021 | 00484MAA4 | $26.6K | $35,083,000 | 0.0% |
| Merus N.V. | COM | N5749R100 | $24.5K | 1,160,014 | 0.0% |
| Xencor, Inc.(XNCR) | COM | 98401F105 | $23.0K | 872,072 | 0.0% |
| Array BioPharma Inc.(ARRYEUR) | COM | 04269X105 | $22.7K | 2,585,913 | 0.0% |
| bluebird bio, Inc. | COM | 09609G100 | $21.7K | 351,441 | 0.0% |
| Derma Sciences, Inc. | COM PAR $.01 | 249827502 | $19.5K | 3,752,390 | 0.0% |
| Aegerion Pharmaceuticals, Inc. | NOTE 2.0% 8/15/2019 | 00767EAB8 | $19.1K | $26,517,000 | 0.0% |
| Galapagos NV(GLPG) | SPONSORED ADR | 36315X101 | $16.7K | 259,894 | 0.0% |
| Idera Pharmaceuticals, Inc. | COM NEW | 45168K306 | $15.4K | 10,272,314 | 0.0% |
| AveXis, Inc. | COM | 05366U100 | $15.0K | 315,300 | 0.0% |
| Intellia Therapeutics, Inc.(NTLA) | COM | 45826J105 | $13.9K | 1,062,120 | 0.0% |
| Aimmune Therapeutics, Inc.(AIMT) | COM | 00900T107 | $13.8K | 673,908 | 0.0% |
| Halozyme Therapeutics, Inc.(HALO) | COM | 40637H109 | $13.7K | 1,391,507 | 0.0% |