Q4 2017 Holdings
Filed 2018-02-14 | 123 holdings | $2.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $819.8M | 27,228,338 | 37.6% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $676.2M | 7,583,084 | 31.0% |
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $376.1M | 3,849,231 | 17.2% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $104.9M | 2,618,818 | 4.8% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $68.7M | 13,997,172 | 3.1% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $60.7M | 961,754 | 2.8% |
| Cerus Corporation(CERS) | COM | 157085101 | $32.9M | 9,745,209 | 1.5% |
| Catalyst Pharmaceuticals, Inc.(CPRX) | COM | 14888U101 | $22.9M | 5,852,153 | 1.0% |
| Agios Pharmaceuticals, Inc.(AGIO) | COM | 00847X104 | $7.4M | 128,666 | 0.3% |
| Incyte Corporation(INCY) | COM | 45337C102 | $3.2M | 34,230,523 | 0.1% |
| Seattle Genetics, Inc. | COM | 812578102 | $2.4M | 45,725,556 | 0.1% |
| Cellectis S.A.(CLLS) | SPONSORED ADS | 15117K103 | $1.5M | 50,000 | 0.1% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $1.0M | 8,553,864 | 0.0% |
| Arbutus Biopharma Corporation(ABUS) | COM | 03879J100 | $912.0K | 180,582 | 0.0% |
| Adaptimmune Therapeutics plc(ADAPY) | SPONSORED ADR | 00653A107 | $668.0K | 100,000 | 0.0% |
| Genomic Health, Inc.(GHDX) | COM | 37244C101 | $471.3K | 13,781,102 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $135.5K | 5,509,560 | 0.0% |
| Aquinox Pharmaceuticals, Inc. | COM | 03842B101 | $128.6K | 10,934,154 | 0.0% |
| Ablynx NV | SPONSORED ADR | 00372Y105 | $104.0K | 4,161,118 | 0.0% |
| Sage Therapeutics, Inc.(SG7) | COM | 78667J108 | $101.5K | 616,514 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR NEW | 023111206 | $90.9K | 22,669,509 | 0.0% |
| AveXis, Inc. | COM | 05366U100 | $85.8K | 775,000 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $77.9K | 1,004,624 | 0.0% |
| Array BioPharma Inc.(ARRYEUR) | COM | 04269X105 | $72.4K | 5,656,196 | 0.0% |
| Spark Therapeutics, Inc. | COM | 84652J103 | $71.2K | 1,384,130 | 0.0% |
| Erytech Pharma S.A. | SPONSORED ADR | 29604W108 | $68.0K | 3,090,069 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $66.2K | 7,288,300 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $59.5K | 2,049,020 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $56.5K | 615,684 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $55.4K | 3,060,641 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $46.5K | 2,549,461 | 0.0% |
| Exelixis, Inc.(EXEL) | COM | 30161Q104 | $45.8K | 1,506,499 | 0.0% |
| Bellicum Pharmaceuticals, Inc. | COM | 079481107 | $42.3K | 5,032,313 | 0.0% |
| Novavax, Inc. | Note 3.75% 2/1/2023 | 670002AB0 | $40.9K | $88,500,000 | 0.0% |
| Idera Pharmaceuticals, Inc. | COM NEW | 45168K306 | $38.6K | 18,315,802 | 0.0% |
| Ignyta, Inc. | COM | 451731103 | $37.0K | 1,384,266 | 0.0% |
| bluebird bio, Inc. | COM | 09609G100 | $35.6K | 200,000 | 0.0% |
| Sangamo Therapeutics, Inc.(SGMO) | COM | 800677106 | $34.7K | 2,113,376 | 0.0% |
| Halozyme Therapeutics, Inc.(HALO) | COM | 40637H109 | $32.0K | 1,581,424 | 0.0% |
| Abeona Therapeutics Inc.(ABEO1EUR) | COM | 00289Y107 | $31.5K | 1,984,364 | 0.0% |
| Acorda Therapeutics, Inc. | NOTE 1.75% 6/15/2021 | 00484MAA4 | $29.8K | $35,083,000 | 0.0% |
| GW Pharmaceuticals plc | ADS | 36197T103 | $29.3K | 221,800 | 0.0% |
| CymaBay Therapeutics, Inc.(CBAYUSD) | COM | 23257D103 | $27.5K | 2,991,775 | 0.0% |
| Aimmune Therapeutics, Inc.(AIMT) | COM | 00900T107 | $25.5K | 673,908 | 0.0% |
| Galapagos NV(GLPG) | SPONSORED ADR | 36315X101 | $24.4K | 259,894 | 0.0% |
| Merus N.V. | COM | N5749R100 | $22.5K | 1,160,014 | 0.0% |
| Intellia Therapeutics, Inc.(NTLA) | COM | 45826J105 | $22.0K | 1,145,453 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $21.8K | 700,000 | 0.0% |
| Xencor, Inc.(XNCR) | COM | 98401F105 | $19.1K | 872,072 | 0.0% |
| Progenics Pharmaceuticals, Inc. | COM | 743187106 | $18.7K | 3,150,808 | 0.0% |