Q3 2018 Holdings
Filed 2018-11-14 | 97 holdings | $3.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $2.1B | 11,959,824 | 52.8% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $735.3M | 7,583,084 | 18.9% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $590.4M | 28,439,114 | 15.1% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $201.1M | 2,837,352 | 5.2% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $115.2M | 15,103,081 | 3.0% |
| Cerus Corporation(CERS) | COM | 157085101 | $77.5M | 10,749,937 | 2.0% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $77.3M | 1,019,557 | 2.0% |
| Catalyst Pharmaceuticals, Inc.(CPRX) | COM | 14888U101 | $11.0M | 2,900,000 | 0.3% |
| Autolus Therapeutics plc(AUTL) | SPON ADS | 05280R100 | $7.2M | 235,294 | 0.2% |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | COM | 04280A100 | $5.9M | 307,496 | 0.2% |
| Seattle Genetics, Inc. | COM | 812578102 | $3.9M | 51,046,060 | 0.1% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $3.8M | 131,250 | 0.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.4M | 34,251,309 | 0.1% |
| Aquestive Therapeutics, Inc.(AQST) | COM | 03843E104 | $1.7M | 99,600 | 0.0% |
| Arcus Biosciences, Inc.(RCUS) | COM | 03969F109 | $1.7M | 121,534 | 0.0% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $1.2M | 8,555,894 | 0.0% |
| Genomic Health, Inc.(GHDX) | COM | 37244C101 | $968.4K | 13,790,970 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $554.3K | 34,069,509 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $250.4K | 1,169,278 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $159.1K | 5,025,298 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $140.5K | 8,399,411 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $123.7K | 5,509,560 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $118.4K | 2,513,462 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $116.1K | 944,624 | 0.0% |
| Array BioPharma Inc.(ARRYEUR) | COM | 04269X105 | $86.0K | 5,656,196 | 0.0% |
| Sage Therapeutics, Inc.(SG7) | COM | 78667J108 | $80.2K | 567,497 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $79.0K | 2,708,200 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $76.5K | 3,000,000 | 0.0% |
| Spark Therapeutics, Inc. | COM | 84652J103 | $75.5K | 1,384,130 | 0.0% |
| GW Pharmaceuticals plc | ADS | 36197T103 | $68.5K | 396,700 | 0.0% |
| CymaBay Therapeutics, Inc.(CBAYUSD) | COM | 23257D103 | $54.5K | 4,917,700 | 0.0% |
| Principia Biopharma Inc.(PRNB) | COM | 74257L108 | $52.2K | 1,787,807 | 0.0% |
| Tricida, Inc.(1T7) | COM | 89610F101 | $48.9K | 1,600,000 | 0.0% |
| Endocyte, Inc. | COM | 29269A102 | $45.3K | 2,548,069 | 0.0% |
| Idera Pharmaceuticals, Inc. | COM | 45168K405 | $43.1K | 4,833,897 | 0.0% |
| Corsicanto II Designated Activity Company | NOTE 3.5% 1/5/2047 | 220485AB2 | $41.7K | 10,000,000 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $37.4K | 1,851,982 | 0.0% |
| Aquinox Pharmaceuticals, Inc. | COM | 03842B101 | $32.0K | 10,934,154 | 0.0% |
| Abeona Therapeutics Inc.(ABEO1EUR) | COM | 00289Y107 | $28.0K | 2,184,364 | 0.0% |
| Solid Biosciences Inc. | COM | 83422E105 | $27.7K | 587,884 | 0.0% |
| Galapagos NV(GLPG) | SPONSORED ADR | 36315X101 | $26.7K | 237,191 | 0.0% |
| Xencor, Inc.(XNCR) | COM | 98401F105 | $23.5K | 602,495 | 0.0% |
| MyoKardia, Inc. | COM | 62857M105 | $23.3K | 357,215 | 0.0% |
| Merus N.V. | COM | N5749R100 | $22.9K | 1,160,014 | 0.0% |
| uniQure N.V.(QURE) | SHS | N90064101 | $22.0K | 605,000 | 0.0% |
| Sangamo Therapeutics, Inc.(SGMO) | COM | 800677106 | $21.8K | 1,283,923 | 0.0% |
| Clementia Pharmaceuticals Inc. | COM | 185575107 | $21.6K | 1,933,624 | 0.0% |
| Zymeworks Inc. | COM | 98985W102 | $20.6K | 1,311,085 | 0.0% |
| Aimmune Therapeutics, Inc.(AIMT) | COM | 00900T107 | $18.4K | 673,908 | 0.0% |
| Neurocrine Biosciences, Inc. | NOTE 2.25% 5/15/2024 | 64125CAD1 | $17.1K | 10,000,000 | 0.0% |