Q4 2018 Holdings
Filed 2019-02-13 | 93 holdings | $3.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $1.7B | 11,959,824 | 48.7% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $646.2M | 7,589,294 | 18.8% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $642.2M | 39,713,842 | 18.6% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $177.8M | 2,837,352 | 5.2% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $121.9M | 15,103,081 | 3.5% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $97.9M | 1,019,557 | 2.8% |
| Cerus Corporation(CERS) | COM | 157085101 | $54.5M | 10,749,937 | 1.6% |
| Catalyst Pharmaceuticals, Inc.(CPRX) | COM | 14888U101 | $5.6M | 2,900,000 | 0.2% |
| Autolus Therapeutics plc(AUTL) | SPON ADS | 05280R100 | $5.1M | 156,773 | 0.1% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $3.9M | 131,250 | 0.1% |
| Seattle Genetics, Inc. | COM | 812578102 | $2.9M | 51,046,060 | 0.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.2M | 34,251,607 | 0.1% |
| Arcus Biosciences, Inc.(RCUS) | COM | 03969F109 | $1.3M | 121,534 | 0.0% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $833.0K | 8,555,894 | 0.0% |
| Genomic Health, Inc.(GHDX) | COM | 37244C101 | $756.4K | 11,744,010 | 0.0% |
| Aquestive Therapeutics, Inc.(AQST) | COM | 03843E104 | $627.0K | 99,600 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $579.7K | 42,592,824 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $131.8K | 1,169,278 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $130.2K | 5,018,104 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $106.6K | 2,513,462 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $84.3K | 3,000,000 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $72.8K | 2,708,200 | 0.0% |
| Array BioPharma Inc.(ARRYEUR) | COM | 04269X105 | $71.8K | 5,041,696 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $64.9K | 9,145,115 | 0.0% |
| Neurocrine Biosciences, Inc. | NOTE 2.25% 5/15/2024 | 64125CAD1 | $63.4K | $53,270,000 | 0.0% |
| Spark Therapeutics, Inc. | COM | 84652J103 | $54.2K | 1,384,130 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $52.2K | 730,355 | 0.0% |
| Principia Biopharma Inc.(PRNB) | COM | 74257L108 | $49.0K | 1,787,807 | 0.0% |
| Clementia Pharmaceuticals Inc. | COM | 185575107 | $43.8K | 3,724,445 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $43.2K | 3,902,421 | 0.0% |
| GW Pharmaceuticals plc | ADS | 36197T103 | $41.7K | 428,345 | 0.0% |
| CymaBay Therapeutics, Inc.(CBAYUSD) | COM | 23257D103 | $38.7K | 4,917,700 | 0.0% |
| Tricida, Inc.(1T7) | COM | 89610F101 | $37.7K | 1,600,000 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $35.4K | 5,509,560 | 0.0% |
| Zymeworks Inc. | COM | 98985W102 | $25.1K | 1,708,472 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $24.3K | 1,851,982 | 0.0% |
| Aquinox Pharmaceuticals, Inc. | COM | 03842B101 | $23.6K | 10,934,154 | 0.0% |
| Audentes Therapeutics, Inc.(BOLDEUR) | COM | 05070R104 | $19.4K | 910,463 | 0.0% |
| uniQure N.V.(QURE) | SHS | N90064101 | $17.4K | 605,000 | 0.0% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $16.3K | 784,674 | 0.0% |
| Merus N.V. | COM | N5749R100 | $16.2K | 1,160,014 | 0.0% |
| Aimmune Therapeutics, Inc.(AIMT) | COM | 00900T107 | $16.1K | 673,908 | 0.0% |
| Xencor, Inc.(XNCR) | COM | 98401F105 | $15.9K | 440,186 | 0.0% |
| Solid Biosciences Inc. | COM | 83422E105 | $15.8K | 587,884 | 0.0% |
| MyoKardia, Inc. | COM | 62857M105 | $15.4K | 315,243 | 0.0% |
| Abeona Therapeutics Inc.(ABEO1EUR) | COM | 00289Y107 | $15.0K | 2,103,164 | 0.0% |
| Ra Pharmaceuticals, Inc. | COM | 74933V108 | $15.0K | 823,113 | 0.0% |
| BioMarin Pharmaceutical Inc. | NOTE 0.599% 8/1/2024 | 09061GAH4 | $14.9K | $15,000,000 | 0.0% |
| Idera Pharmaceuticals, Inc. | COM PAR | 45168K405 | $13.4K | 4,836,237 | 0.0% |
| Aeglea BioTherapeutics, Inc.(AGLEUSD) | COM | 00773J103 | $12.8K | 1,713,604 | 0.0% |