Q1 2019 Holdings
Filed 2019-05-15 | 96 holdings | $4.1B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| BeiGene, Ltd.(ONC) | SPONSORED ADR | 07725L102 | $1.6B | 11,959,824 | 38.6% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $1.1B | 39,713,842 | 26.1% |
| BioMarin Pharmaceutical Inc.(BMRN) | COM | 09061G101 | $674.2M | 7,589,294 | 16.5% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $399.0M | 3,390,270 | 9.8% |
| argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $127.3M | 1,019,557 | 3.1% |
| BioCryst Pharmaceuticals, Inc.(BCRX) | COM | 09058V103 | $123.1M | 15,118,081 | 3.0% |
| Cerus Corporation(CERS) | COM | 157085101 | $67.0M | 10,749,937 | 1.6% |
| Axsome Therapeutics, Inc.(AXSM) | COM | 05464T104 | $17.1M | 1,200,000 | 0.4% |
| Catalyst Pharmaceuticals, Inc.(CPRX) | COM | 14888U101 | $14.8M | 2,900,000 | 0.4% |
| Autolus Therapeutics plc(AUTL) | SPON ADS | 05280R100 | $4.9M | 156,773 | 0.1% |
| Seattle Genetics, Inc. | COM | 812578102 | $3.7M | 51,049,760 | 0.1% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $3.0M | 131,250 | 0.1% |
| Incyte Corporation(INCY) | COM | 45337C102 | $2.9M | 34,271,827 | 0.1% |
| CytomX Therapeutics, Inc.(CTMX) | COM | 23284F105 | $2.1M | 194,377 | 0.1% |
| Arcus Biosciences, Inc.(RCUS) | COM | 03969F109 | $1.5M | 121,534 | 0.0% |
| Alexion Pharmaceuticals, Inc.(ALXN) | COM | 015351109 | $1.2M | 8,558,068 | 0.0% |
| Amarin Corporation plc | SPONSORED ADR | 023111206 | $897.0K | 43,210,459 | 0.0% |
| Genomic Health, Inc.(GHDX) | COM | 37244C101 | $714.4K | 10,198,943 | 0.0% |
| Aquestive Therapeutics, Inc.(AQST) | COM | 03843E104 | $688.0K | 99,600 | 0.0% |
| Mirati Therapeutics, Inc.(MRTXEUR) | COM | 60468T105 | $184.2K | 2,513,462 | 0.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $146.5K | 1,169,278 | 0.0% |
| Heron Therapeutics, Inc.(HRTX) | COM | 427746102 | $122.6K | 5,018,104 | 0.0% |
| Clementia Pharmaceuticals Inc. | COM | 185575107 | $97.2K | 3,724,445 | 0.0% |
| Neurocrine Biosciences, Inc.(NBIX) | COM | 64125C109 | $96.8K | 1,098,670 | 0.0% |
| Array BioPharma Inc.(ARRYEUR) | COM | 04269X105 | $93.7K | 3,842,289 | 0.0% |
| Invitae Corporation(NVTA1EUR) | COM | 46185L103 | $91.4K | 3,902,421 | 0.0% |
| Spark Therapeutics, Inc. | COM | 84652J103 | $85.6K | 751,927 | 0.0% |
| CymaBay Therapeutics, Inc.(CBAYUSD) | COM | 23257D103 | $75.8K | 5,707,411 | 0.0% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $74.2K | 2,708,200 | 0.0% |
| GW Pharmaceuticals plc | ADS | 36197T103 | $72.2K | 428,345 | 0.0% |
| Neurocrine Biosciences, Inc. | NOTE 2.25% 5/15/2024 | 64125CAD1 | $72.0K | $53,270,000 | 0.0% |
| Tricida, Inc.(1T7) | COM | 89610F101 | $69.6K | 1,803,238 | 0.0% |
| Audentes Therapeutics, Inc.(BOLDEUR) | COM | 05070R104 | $66.9K | 1,715,183 | 0.0% |
| Principia Biopharma Inc.(PRNB) | COM | 74257L108 | $60.8K | 1,787,807 | 0.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $60.4K | 2,077,601 | 0.0% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $59.7K | 9,145,115 | 0.0% |
| Kiniksa Pharmaceuticals, Ltd. | COM CL A | G5269C101 | $54.2K | 3,000,000 | 0.0% |
| MyoKardia, Inc. | COM | 62857M105 | $52.8K | 1,016,306 | 0.0% |
| DBV Technologies S.A. | SPONSORED ADR | 23306J101 | $42.5K | 5,509,560 | 0.0% |
| uniQure N.V.(QURE) | SHS | N90064101 | $36.1K | 605,000 | 0.0% |
| Aquinox Pharmaceuticals, Inc. | COM | 03842B101 | $29.5K | 10,934,154 | 0.0% |
| Zymeworks Inc. | COM | 98985W102 | $27.6K | 1,708,472 | 0.0% |
| Krystal Biotech, Inc.(KRYS) | COM | 501147102 | $25.8K | 784,674 | 0.0% |
| Ra Pharmaceuticals, Inc. | COM | 74933V108 | $18.4K | 823,113 | 0.0% |
| Merus N.V. | COM | N5749R100 | $17.1K | 1,160,014 | 0.0% |
| BioMarin Pharmaceutical Inc. | NOTE 0.599% 8/1/2024 | 09061GAH4 | $15.4K | $15,000,000 | 0.0% |
| Aimmune Therapeutics, Inc.(AIMT) | COM | 00900T107 | $15.1K | 673,908 | 0.0% |
| Aeglea BioTherapeutics, Inc.(AGLEUSD) | COM | 00773J103 | $13.8K | 1,713,604 | 0.0% |
| Xencor, Inc.(XNCR) | COM | 98401F105 | $13.3K | 428,120 | 0.0% |
| Idera Pharmaceuticals, Inc. | COM PAR | 45168K405 | $12.3K | 4,839,895 | 0.0% |