Q4 2023 Holdings
Filed 2024-02-14 | 136 holdings | $1.1B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Krystal Biotech Inc(KRYS)Put | COM | 501147102 | $51.1M | 412,000 | 4.8% |
| Cytokinetics Inc(CYTK)Call | COM NEW | 23282W605 | $50.4M | 603,500 | 4.7% |
| Spdr SER TR(XBI)Put | S&P BIOTECH | 78464A870 | $49.1M | 550,000 | 4.6% |
| ELI Lilly & Co(LLY)Put | COM | 532457108 | $40.8M | 70,000 | 3.8% |
| Crispr Therapeutics AG(CRSP)Put | NAMEN AKT | H17182108 | $40.7M | 649,400 | 3.8% |
| Alnylam Pharmaceuticals Inc(ALNY)Call | COM | 02043Q107 | $32.5M | 169,700 | 3.0% |
| Argenx SE(ARGX)Put | SPONSORED ADR | 04016X101 | $29.7M | 78,100 | 2.8% |
| Argenx SE(ARGX)Call | SPONSORED ADR | 04016X101 | $29.7M | 78,100 | 2.8% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $26.5M | 70,000 | 2.5% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $24.2M | 680,370 | 2.3% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $23.8M | 590,243 | 2.2% |
| Prothena Corp PLC(PRTA)Call | SHS | G72800108 | $21.8M | 600,000 | 2.0% |
| Abbvie Inc(ABBV)Call | COM | 00287Y109 | $20.5M | 132,500 | 1.9% |
| Spdr SER TR(XHB) | S&P HOMEBUILD | 78464A888 | $19.1M | 200,000 | 1.8% |
| Amylyx Pharmaceuticals Inc(AMLX)Call | COM | 03237H101 | $19.1M | 1,298,400 | 1.8% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $19.1M | 473,126 | 1.8% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $19.0M | 258,142 | 1.8% |
| Alnylam Pharmaceuticals Inc(ALNY)Put | COM | 02043Q107 | $18.9M | 98,600 | 1.8% |
| Karuna Therapeutics IncCall | COM | 48576A100 | $18.5M | 58,600 | 1.7% |
| Sarepta Therapeutics Inc(SRPT)Call | COM | 803607100 | $17.6M | 182,600 | 1.6% |
| Lantheus Hldgs Inc(LNTH)Call | COM | 516544103 | $16.7M | 270,000 | 1.6% |
| Prothena Corp PLC(PRTA)Put | SHS | G72800108 | $15.2M | 418,400 | 1.4% |
| Acelyrin Inc | COM | 00445A100 | $14.9M | 1,991,005 | 1.4% |
| Immunogen Inc(IMGNEUR)Call | COM | 45253H101 | $13.5M | 456,800 | 1.3% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $12.9M | 877,500 | 1.2% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $12.8M | 132,640 | 1.2% |
| Immunovant Inc(IMVT)Call | COM | 45258J102 | $12.7M | 300,700 | 1.2% |
| Krystal Biotech Inc(KRYS)Call | COM | 501147102 | $12.4M | 100,000 | 1.2% |
| Moonlake Immunotherapeutics(MLTX)Put | CLASS A ORD | 61559X104 | $12.1M | 200,600 | 1.1% |
| Annexon Inc(ANNX) | COM | 03589W102 | $12.0M | 2,650,000 | 1.1% |
| Biomea Fusion Inc(BMEA)Call | COM | 09077A106 | $11.3M | 777,600 | 1.1% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $11.3M | 194,982 | 1.1% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $10.5M | 518,519 | 1.0% |
| Amgen Inc(AMGN)Call | COM | 031162100 | $10.1M | 35,000 | 0.9% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $9.8M | 233,394 | 0.9% |
| Sarepta Therapeutics Inc(SRPT)Put | COM | 803607100 | $9.8M | 101,800 | 0.9% |
| Alexandria Real Estate EQ in(ARE)Put | COM | 015271109 | $9.3M | 73,300 | 0.9% |
| Alpine Immune Sciences Inc(NVLSEUR) | COM | 02083G100 | $9.3M | 487,248 | 0.9% |
| Eyepoint Pharmaceuticals Inc(EYPT)Call | COM NEW | 30233G209 | $9.0M | 391,000 | 0.8% |
| Apellis Pharmaceuticals Inc(APLS)Call | COM | 03753U106 | $9.0M | 150,000 | 0.8% |
| Corcept Therapeutics Inc(CORT)Call | COM | 218352102 | $8.8M | 271,300 | 0.8% |
| Corcept Therapeutics Inc(CORT)Put | COM | 218352102 | $8.8M | 271,300 | 0.8% |
| Eyepoint Pharmaceuticals Inc(EYPT) | COM NEW | 30233G209 | $8.5M | 368,130 | 0.8% |
| Catalyst Pharmaceuticals Inc(CPRX) | COM | 14888U101 | $8.5M | 505,862 | 0.8% |
| Marinus Pharmaceuticals Inc(MRNS*) | COM NEW | 56854Q200 | $8.1M | 746,069 | 0.8% |
| Dyne Therapeutics Inc(DYN)Call | COM | 26818M108 | $8.1M | 607,600 | 0.8% |
| Nuvalent Inc(NUVL)Call | COM | 670703107 | $7.7M | 104,400 | 0.7% |
| Arcus Biosciences Inc(RCUS)Call | COM | 03969F109 | $7.6M | 400,000 | 0.7% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $7.3M | 319,000 | 0.7% |
| Biomea Fusion Inc(BMEA)Put | COM | 09077A106 | $7.3M | 500,000 | 0.7% |