Q4 2025 Holdings
Filed 2026-02-17 | 37 holdings | $1.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $219.0M | 6,165,223 | 14.0% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $173.8M | 3,433,051 | 11.1% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $169.2M | 8,050,959 | 10.8% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $161.4M | 5,943,180 | 10.3% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $134.8M | 2,922,335 | 8.6% |
| Biocryst Pharmaceuticals Inc(BCRX) | COM | 09058V103 | $73.1M | 9,366,526 | 4.7% |
| Beam Therapeutics Inc(BEAM) | COM | 07373V105 | $67.6M | 2,440,214 | 4.3% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $45.8M | 1,470,541 | 2.9% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $41.1M | 1,564,492 | 2.6% |
| CG Oncology Inc(CGON) | COM | 156944100 | $39.3M | 945,830 | 2.5% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $38.2M | 8,966,077 | 2.4% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $37.4M | 1,970,357 | 2.4% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $36.9M | 2,169,105 | 2.4% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $32.2M | 3,114,132 | 2.1% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $29.7M | 856,462 | 1.9% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $29.5M | 934,799 | 1.9% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $29.2M | 1,810,954 | 1.9% |
| Beam Therapeutics Inc(BEAM)Call | COM | 07373V105 | $26.0M | 937,000 | 1.7% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $22.8M | 908,607 | 1.5% |
| Dynavax Technologies Corp(DVAX) | COM NEW | 268158201 | $21.2M | 1,375,632 | 1.4% |
| Burning Rock Biotech LTD(BNR) | SPONSORED ADS | 12233L206 | $20.0M | 994,883 | 1.3% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $19.8M | 517,884 | 1.3% |
| Pharvaris N V(PHVS) | COM | N69605108 | $17.8M | 640,395 | 1.1% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $13.5M | 1,492,898 | 0.9% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $12.0M | 1,424,259 | 0.8% |
| Biohaven LTD(BHVN) | COM | G1110E107 | $7.9M | 702,884 | 0.5% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $7.4M | 784,606 | 0.5% |
| Sutro Biopharma Inc(STRO) | COM SHS | 869367201 | $5.5M | 479,590 | 0.4% |
| Amarin Corp PLC(EH3) | SPONSORED ADR | 023111404 | $5.4M | 389,273 | 0.3% |
| Geron Corp(GERN) | COM | 374163103 | $4.6M | 3,456,318 | 0.3% |
| Climb BIO Inc(CLYM) | COM | 28658R106 | $4.1M | 1,028,341 | 0.3% |
| Caribou Biosciences Inc(CRBU) | COM | 142038108 | $4.0M | 2,503,302 | 0.3% |
| Omeros Corp(OMER)Put | COM | 682143102 | $3.4M | 200,000 | 0.2% |
| Evommune Inc(EVMN) | COM SHS | 30054Y107 | $3.2M | 185,482 | 0.2% |
| Proqr Thrapeutics N V | SHS EURO | N71542109 | $3.2M | 1,566,317 | 0.2% |
| Alector Inc(ALEC) | COM | 014442107 | $3.1M | 2,000,000 | 0.2% |
| Prelude Therapeutics Inc(PRLD) | COM | 74065P101 | $2.3M | 788,867 | 0.1% |