Q3 2025 Holdings
Filed 2025-11-14 | 81 holdings | $2.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $119.3M | 600,000 | 5.4% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $102.6M | 1,250,000 | 4.6% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $95.1M | 1,100,000 | 4.3% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $84.9M | 1,000,000 | 3.8% |
| Alcon AG(ALC) | ORD SHS | H01301128 | $82.0M | 1,100,000 | 3.7% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $80.5M | 5,100,000 | 3.6% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $76.8M | 9,750,000 | 3.5% |
| Globus Medical Inc(GMED) | CL A | 379577208 | $71.6M | 1,250,000 | 3.2% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $70.3M | 1,075,000 | 3.2% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $65.9M | 500,000 | 3.0% |
| Becton Dickinson & Co(BDX) | COM | 075887109 | $60.8M | 325,000 | 2.7% |
| Scholar Rock Holding Corp(SRRK) | COM | 80706P103 | $55.9M | 1,500,000 | 2.5% |
| Immatics NV(IMTX) | SHS | N44445109 | $54.1M | 6,350,000 | 2.4% |
| Repligen Corp(RGEN) | COM | 759916109 | $53.5M | 400,000 | 2.4% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $46.4M | 1,180,000 | 2.1% |
| BioMarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $45.0M | 830,000 | 2.0% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $44.2M | 1,100,000 | 2.0% |
| Dexcom Inc(DXCM) | COM | 252131107 | $43.7M | 650,000 | 2.0% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $39.8M | 725,000 | 1.8% |
| Biogen Inc(BIIB) | COM | 09062X103 | $38.5M | 275,000 | 1.7% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $38.3M | 400,000 | 1.7% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $36.1M | 4,956,000 | 1.6% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $35.1M | 2,775,000 | 1.6% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $33.9M | 2,425,000 | 1.5% |
| Abbott Laboratories(ABT) | COM | 002824100 | $33.5M | 250,000 | 1.5% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $33.0M | 500,000 | 1.5% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $32.1M | 3,475,000 | 1.4% |
| Crinetics Pharmaceuticals Inc(CRNX) | COM | 22663K107 | $31.2M | 750,000 | 1.4% |
| Celldex Therapeutics Inc(CLDX) | COM NEW | 15117B202 | $31.2M | 1,205,000 | 1.4% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $30.1M | 1,765,000 | 1.4% |
| Danaher Corp(DHR) | COM | 235851102 | $29.7M | 150,000 | 1.3% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $29.4M | 630,000 | 1.3% |
| Rapport Therapeutics Inc(RAPP) | COM | 75383L102 | $28.2M | 950,000 | 1.3% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $23.7M | 1,160,000 | 1.1% |
| Geron Corp(GERN) | COM | 374163103 | $23.6M | 17,225,000 | 1.1% |
| Belite Bio Inc(BLTE) | SPONSORED ADS | 07782B104 | $23.1M | 312,500 | 1.0% |
| Ultragenyx Pharmaceutical Inc(RARE) | COM | 90400D108 | $22.6M | 750,000 | 1.0% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $22.1M | 760,000 | 1.0% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $21.6M | 3,250,000 | 1.0% |
| Black Diamond Therapeutics Inc(BDTX) | COM | 09203E105 | $21.0M | 5,550,000 | 0.9% |
| Day One Biopharmaceuticals Inc(DAWN) | COM | 23954D109 | $18.9M | 2,675,000 | 0.9% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $18.4M | 2,975,000 | 0.8% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $18.2M | 150,000 | 0.8% |
| Taysha Gene Therapies Inc(TSHA) | COM SHS | 877619106 | $18.0M | 5,500,000 | 0.8% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $16.9M | 425,000 | 0.8% |
| Savara Inc(SVRA) | COM | 805111101 | $14.3M | 4,015,000 | 0.6% |
| Bruker Corp(BRKR) | COM | 116794108 | $14.3M | 440,000 | 0.6% |
| Regeneron Pharmaceuticals Inc(REGN) | COM | 75886F107 | $14.1M | 25,000 | 0.6% |
| uniQure NV(QURE) | SHS | N90064101 | $13.1M | 225,000 | 0.6% |
| Beta Bionics Inc(BBNX) | COM | 08659B102 | $11.9M | 600,000 | 0.5% |