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Opaleye Management Inc.

Portfolio Profile

CIK: 0001595855 | BOSTON, MA

Investment Profile

Style

Aggressive Growth

Turnover

Medium

Orientation

Concentrated trader
$1.1B
AUM
58
Positions
64.76%
Top 10 Conc.
88.49%
Top 25 Conc.

Top Holdings

#SecuritySharesValue% of Portfolio
1Liquidia Corporation(LQDA)2,447,500$195.1M17.67%
2Eton Pharmaceuticals Inc(ETON)2,860,000$103.5M9.38%
3Harrow Inc(HROW)2,400,000$101.9M9.23%
4Disc Medicine Inc(IRON)855,000$62.5M5.66%
5Urogen Pharma LTD(URGN)1,439,996$53.0M4.80%
6

Sector Allocation

Latest filing, equity positions only

Healthcare87.15% · $962.3M
Unclassified12.85% · $141.9M

Sector Rotation

Quarter-over-quarter weight changes

SectorPrev %Curr %Change
Healthcare88.86%87.15%-1.71%
Unclassified11.14%12.85%+1.71%

Cap Size Rotation

Quarter-over-quarter weight changes by market cap

AUM History

$307.4M | 41 pos.
$376.1M | 47 pos.
$458.9M | 52 pos.
$437.7M | 51 pos.
$599.6M | 44 pos.
$571.4M | 39 pos.
Apogee Therapeutics Inc(APGE)
390,000
$51.8M
4.69%
7Meiragtx Hldgs PLC(MGTX)3,550,000$48.0M4.34%
8Sol-Gel Technologies LTD(SLGL)500,000$37.1M3.36%
9Rezolute Inc(RZLT)6,300,000$32.8M2.97%
10TG Therapeutics Inc(TGTX)535,000$29.4M2.66%
Cap SizePrev %Curr %Change
Small Cap41.45%37.15%-4.3%
Mid Cap32.47%36.49%+4.02%
Unclassified11.14%12.85%+1.71%
Micro Cap13.67%11.82%-1.85%
Large Cap1.28%1.7%+0.42%
$449.2M | 45 pos.
$494.1M | 41 pos.
$707.3M | 43 pos.
$757.9M | 54 pos.
$759.2M | 54 pos.
$1.1B | 58 pos.
Q3
23
Q4
23
Q1
24
Q2
24
Q3
24
Q4
24
Q1
25
Q2
25
Q3
25
Q4
25
Q1
26
Q2
26

Recent Activity

Quarter-over-quarter position changes

13
New
9
Closed
15
Increased
13
Decreased
17
Unchanged