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5AM Venture Management, LLC

Portfolio Profile

CIK: 0001799883 | SAN FRANCISCO, CA

Investment Profile

Style

Deep Value

Turnover

Low

Orientation

Concentrated trader
$287.9M
AUM
16
Positions
85.57%
Top 10 Conc.
100%
Top 25 Conc.

Top Holdings

#SecuritySharesValue% of Portfolio
1Maplight Therapeutics Inc(MPLT)950,011$34.0M11.83%
2Tyra Biosciences Inc(TYRA)1,029,298$32.9M11.42%
3Entrada Therapeutics Inc(TRDA)4,056,379$29.9M10.37%
4Pharvaris N V(PHVS)797,600$27.6M9.58%
5Camp4 Therapeutics Corp(CAMP)5,869,091$25.6M8.91%

Sector Allocation

Latest filing, equity positions only

Healthcare78.59% · $226.3M
Unclassified21.41% · $61.6M

Sector Rotation

Quarter-over-quarter weight changes

SectorPrev %Curr %Change
Healthcare85.42%78.59%-6.83%
Unclassified14.58%21.41%+6.83%

Cap Size Rotation

Quarter-over-quarter weight changes by market cap

AUM History

$401.4M | 24 pos.
$347.5M | 26 pos.
$377.0M | 25 pos.
$446.6M | 26 pos.
$447.1M | 28 pos.
$484.0M | 28 pos.
6
Artiva Biotherapeutics Inc(ARTV)
2,353,304
$22.8M
7.93%
7Tectonic Therapeutic Inc(TECX)606,660$20.9M7.24%
8Zentalis Pharmaceuticals Inc(ZNTL)3,947,913$19.1M6.65%
9Celldex Therapeutics Inc New(CLDX)497,270$18.5M6.43%
10Eyepoint Inc(EYPT)1,050,000$15.0M5.22%
Cap SizePrev %Curr %Change
Micro Cap22.43%32.28%+9.85%
Small Cap28.25%31.07%+2.82%
Unclassified14.58%21.41%+6.83%
Mid Cap34.74%15.24%-19.5%
$419.1M | 31 pos.
$264.4M | 31 pos.
$273.0M | 25 pos.
$318.1M | 21 pos.
$360.2M | 20 pos.
$287.9M | 16 pos.
Q2
23
Q3
23
Q4
23
Q1
24
Q2
24
Q3
24
Q4
24
Q1
25
Q3
25
Q4
25
Q1
26
Q2
26

Recent Activity

Quarter-over-quarter position changes

0
New
4
Closed
0
Increased
1
Decreased
15
Unchanged