Design Therapeutics Inc (DSGN)

Q2 2026 vs Q3 2026

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options 13D/13G Peers Targeting Trading Summary Profile

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Geode Capital Management, LLC

INCREASED

Shares973,710 from 958,417

Change+15,293 (+2%)

Value$12.2M (-$1.6M)

Filed 2026-11-06

Dimensional Fund Advisors LP

INCREASED

Shares727,567 from 694,743

Change+32,824 (+5%)

Value$9.1M (-$906.0K)

Filed 2026-11-04

China Universal Asset Management Co., Ltd.

INCREASED

Shares112,419 from 89,940

Change+22,479 (+25%)

Value$1.4M (+$117.3K)

Filed 2026-10-28

MacKenzie Financial Corp

NEW

Shares110,764

Change+110,764

Value$1.4M

Filed 2026-11-02

Bank of New York Mellon Corp

INCREASED

Shares97,731 from 92,069

Change+5,662 (+6%)

Value$1.2M (-$103.8K)

Filed 2026-11-05

Alps Advisors Inc

INCREASED

Shares82,927 from 63,391

Change+19,536 (+31%)

Value$1.0M (+$125.1K)

Filed 2026-11-03

Strs Ohio

INCREASED

Shares64,000 from 50,500

Change+13,500 (+27%)

Value$804.5K (+$73.7K)

Filed 2026-10-30

Russell Investments Group, Ltd.

DECREASED

Shares50,505 from 66,859

Change-16,354 (-24%)

Value$634.8K (-$332.6K)

Filed 2026-11-06

Y-Intercept (Hong Kong) Ltd

INCREASED

Shares32,468 from 12,910

Change+19,558 (+151%)

Value$408.1K (+$221.3K)

Filed 2026-10-16

Creative Planning

INCREASED

Shares32,089 from 15,844

Change+16,245 (+103%)

Value$403.4K (+$174.1K)

Filed 2026-11-02

Oppenheimer & Co Inc

DECREASED

Shares31,646 from 32,087

Change-441 (-1%)

Value$397.8K (-$66.5K)

Filed 2026-10-26

Deutsche Bank Ag\

DECREASED

Shares26,799 from 30,613

Change-3,814 (-12%)

Value$336.9K (-$106.1K)

Filed 2026-11-06

AlphaCentric Advisors LLC

INCREASED

Shares22,505 from 21,537

Change+968 (+4%)

Value$282.9K (-$28.8K)

Filed 2026-11-03

Citigroup Inc

INCREASED

Shares19,638 from 15,880

Change+3,758 (+24%)

Value$246.8K (+$17.1K)

Filed 2026-11-04

Profund Advisors LLC

NEW

Shares14,351

Change+14,351

Value$180.4K

Filed 2026-10-29

Barclays PLC

INCREASED

Shares11,771 from 11,707

Change+64 (+1%)

Value$148.0K (-$21.4K)

Filed 2026-11-06

Clearstead Advisors, LLC

INCREASED

Shares5,611 from 5,610

Change+1 (+0%)

Value$70.5K (-$10.6K)

Filed 2026-11-06

Caitong International Asset Management Co., Ltd

INCREASED

Shares4,092 from 1,259

Change+2,833 (+225%)

Value$51.4K (+$33.2K)

Filed 2026-10-29

Mirae Asset Global Investments Co., Ltd.

INCREASED

Shares3,198 from 2,793

Change+405 (+15%)

Value$40.2K (-$216)

Filed 2026-11-03

Nisa Investment Advisors, LLC

DECREASED

Shares3,124 from 14,824

Change-11,700 (-79%)

Value$39.3K (-$175.2K)

Filed 2026-10-20

Gamma Investing LLC

INCREASED

Shares2,135 from 1,450

Change+685 (+47%)

Value$26.8K (+$5.9K)

Filed 2026-10-08

State of Wyoming

DECREASED

Shares1,754 from 2,566

Change-812 (-32%)

Value$22.0K (-$15.1K)

Filed 2026-10-28

PNC Financial Services Group, Inc.

DECREASED

Shares1,689 from 1,816

Change-127 (-7%)

Value$21.2K (-$5.0K)

Filed 2026-11-06

GF Fund Management Co. Ltd.

INCREASED

Shares1,315 from 1,209

Change+106 (+9%)

Value$16.5K (-$964)

Filed 2026-10-26

Sterling Capital Management LLC

INCREASED

Shares1,009 from 108

Change+901 (+834%)

Value$12.7K (+$11.1K)

Filed 2026-10-22

Larson Financial Group LLC

INCREASED

Shares642 from 181

Change+461 (+255%)

Value$8.1K (+$5.5K)

Filed 2026-11-05

EverSource Wealth Advisors, LLC

INCREASED

Shares603 from 25

Change+578 (+2312%)

Value$7.6K (+$7.2K)

Filed 2026-11-04

Private Wealth Management Group, LLC

DECREASED

Shares421 from 533

Change-112 (-21%)

Value$5.3K (-$2.4K)

Filed 2026-10-19

SJS Investment Consulting Inc.

INCREASED

Shares272 from 4

Change+268 (+6700%)

Value$3.4K (+$3.4K)

Filed 2026-10-26

Physician Wealth Advisors, Inc.

UNCHANGED

Shares268 from 268

Change0 (0%)

Value$3.4K (-$509)

Filed 2026-10-20

Allworth Financial LP

UNCHANGED

Shares96 from 96

Change0 (0%)

Value$1.4K ($0)

Filed 2026-11-06

Versant Capital Management, Inc

UNCHANGED

Shares86 from 86

Change0 (0%)

Value$1.1K (-$163)

Filed 2026-10-02

Parkside Financial Bank & Trust

NEW

Shares70

Change+70

Value$880

Filed 2026-10-27

Simplex Trading, LLC

DECREASED

Shares47 from 172

Change-125 (-73%)

Value$590 (-$1.9K)

Filed 2026-11-04

Farther Finance Advisors, LLC

INCREASED

Shares38 from 20

Change+18 (+90%)

Value$478 (+$189)

Filed 2026-10-08

Silver Grove Financial Group, Inc.

DECREASED

Shares36 from 58

Change-22 (-38%)

Value$453 (-$386)

Filed 2026-11-05

Root Financial Partners, LLC

NEW

Shares35

Change+35

Value$440

Filed 2026-10-21

US Bancorp \de\

UNCHANGED

Shares26 from 26

Change0 (0%)

Value$327 (-$49)

Filed 2026-11-05

True Wealth Design, LLC

INCREASED

Shares23 from 18

Change+5 (+28%)

Value$290 (+$29)

Filed 2026-10-13

Capital Advisors, Ltd. LLC

UNCHANGED

Shares12 from 12

Change0 (0%)

Value$0 ($0)

Filed 2026-10-27

SBI Securities Co., Ltd.

UNCHANGED

Shares10 from 10

Change0 (0%)

Value$126 (-$19)

Filed 2026-10-22

Essential Partners LLC

UNCHANGED

Shares1 from 1

Change0 (0%)

Value$13 (-$1)

Filed 2026-10-14

MassMutual Private Wealth & Trust, FSB

CLOSED

Shares0 from 239

Change-239 (-100%)

Value$0 (-$3.5K)

Filed 2026-10-05

Stone House Investment Management, LLC

CLOSED

Shares0 from 239

Change-239 (-100%)

Value$0 (-$3.5K)

Filed 2026-10-23

SR One Capital Management, LP

N/A

Shares— from 6,526,476

Change-6,526,476 (-100%)

Value—

Logos Global Management LP

N/A

Shares— from 3,000,000

Change-3,000,000 (-100%)

Value—

Baker Bros. Advisors LP

N/A

Shares— from 2,678,430

Change-2,678,430 (-100%)

Value—

Driehaus Capital Management LLC

N/A

Shares— from 2,661,115

Change-2,661,115 (-100%)

Value—

BlackRock, Inc.

N/A

Shares— from 2,660,024

Change-2,660,024 (-100%)

Value—

Point72 Asset Management, L.P.

N/A

Shares— from 2,366,453

Change-2,366,453 (-100%)

Value—

Trails Edge Capital Partners, LP

N/A

Shares— from 2,001,282

Change-2,001,282 (-100%)

Value—

Frazier Life Sciences Management, L.P.

N/A

Shares— from 1,809,854

Change-1,809,854 (-100%)

Value—

Vivo Capital, LLC

N/A

Shares— from 1,612,903

Change-1,612,903 (-100%)

Value—

Vanguard Capital Management LLC

N/A

Shares— from 1,571,022

Change-1,571,022 (-100%)

Value—

Caption Management, LLC

N/A

Shares— from 1,118,098

Change-1,118,098 (-100%)

Value—

Almitas Capital LLC

N/A

Shares— from 1,026,893

Change-1,026,893 (-100%)

Value—

Sofinnova Investments, Inc.

N/A

Shares— from 865,135

Change-865,135 (-100%)

Value—

FMR LLC

N/A

Shares— from 776,462

Change-776,462 (-100%)

Value—

Morgan Stanley

N/A

Shares— from 765,425

Change-765,425 (-100%)

Value—

State Street Corp

N/A

Shares— from 736,221

Change-736,221 (-100%)

Value—

Woodline Partners LP

N/A

Shares— from 700,354

Change-700,354 (-100%)

Value—

Goldman Sachs Group Inc

N/A

Shares— from 656,584

Change-656,584 (-100%)

Value—

Jacobs Levy Equity Management, Inc

N/A

Shares— from 565,597

Change-565,597 (-100%)

Value—

Acadian Asset Management LLC

N/A

Shares— from 537,479

Change-537,479 (-100%)

Value—

Siren, L.L.C.

N/A

Shares— from 523,212

Change-523,212 (-100%)

Value—

Qube Research & Technologies Ltd

N/A

Shares— from 437,079

Change-437,079 (-100%)

Value—

Renaissance Technologies LLC

N/A

Shares— from 387,913

Change-387,913 (-100%)

Value—

Kennedy Capital Management LLC

N/A

Shares— from 384,036

Change-384,036 (-100%)

Value—

Northern Trust Corp

N/A

Shares— from 353,197

Change-353,197 (-100%)

Value—

Algert Global LLC

N/A

Shares— from 296,085

Change-296,085 (-100%)

Value—

Acuta Capital Partners, LLC

N/A

Shares— from 282,564

Change-282,564 (-100%)

Value—

Charles Schwab Investment Management Inc

N/A

Shares— from 271,264

Change-271,264 (-100%)

Value—

Vanguard Portfolio Management LLC

N/A

Shares— from 251,442

Change-251,442 (-100%)

Value—

Vanguard Fiduciary Trust Co

N/A

Shares— from 230,202

Change-230,202 (-100%)

Value—

Prudential Financial Inc

N/A

Shares— from 224,170

Change-224,170 (-100%)

Value—

D. E. Shaw & Co., Inc.

N/A

Shares— from 195,645

Change-195,645 (-100%)

Value—

Eversept Partners, LP

N/A

Shares— from 190,000

Change-190,000 (-100%)

Value—

KVP Capital Advisors, LP

N/A

Shares— from 185,000

Change-185,000 (-100%)

Value—

J. Goldman & Co LP

N/A

Shares— from 176,770

Change-176,770 (-100%)

Value—

Millennium Management LLC

N/A

Shares— from 147,714

Change-147,714 (-100%)

Value—

Raymond James Financial Inc

N/A

Shares— from 138,521

Change-138,521 (-100%)

Value—

Balyasny Asset Management L.P.

N/A

Shares— from 111,103

Change-111,103 (-100%)

Value—

Elmind Capital, LP

N/A

Shares— from 107,900

Change-107,900 (-100%)

Value—

Nuveen, LLC

N/A

Shares— from 104,734

Change-104,734 (-100%)

Value—

Dafna Capital Management LLC

N/A

Shares— from 102,600

Change-102,600 (-100%)

Value—

Citadel Advisors LLC

N/A

Shares— from 81,971

Change-81,971 (-100%)

Value—

SummitTX Capital, L.P.

N/A

Shares— from 80,663

Change-80,663 (-100%)

Value—

American Century Companies Inc

N/A

Shares— from 76,825

Change-76,825 (-100%)

Value—

Palumbo Wealth Management LLC

N/A

Shares— from 71,744

Change-71,744 (-100%)

Value—

AQR Capital Management LLC

N/A

Shares— from 71,114

Change-71,114 (-100%)

Value—

Ameriprise Financial Inc

N/A

Shares— from 67,598

Change-67,598 (-100%)

Value—

State of Wisconsin Investment Board

N/A

Shares— from 59,249

Change-59,249 (-100%)

Value—

Verdad Advisers, LP

N/A

Shares— from 47,557

Change-47,557 (-100%)

Value—

Bank of America Corp

N/A

Shares— from 43,728

Change-43,728 (-100%)

Value—

Alliancebernstein L.P.

N/A

Shares— from 43,230

Change-43,230 (-100%)

Value—

ExodusPoint Capital Management, LP

N/A

Shares— from 41,286

Change-41,286 (-100%)

Value—

Rhumbline Advisers

N/A

Shares— from 38,132

Change-38,132 (-100%)

Value—

Vanguard Global Advisers, LLC

N/A

Shares— from 35,534

Change-35,534 (-100%)

Value—

UBS Group AG

N/A

Shares— from 34,761

Change-34,761 (-100%)

Value—

Susquehanna Portfolio Strategies, LLC

N/A

Shares— from 33,375

Change-33,375 (-100%)

Value—

Two Sigma Investments, LP

N/A

Shares— from 32,925

Change-32,925 (-100%)

Value—

Canada Pension Plan Investment Board

N/A

Shares— from 32,600

Change-32,600 (-100%)

Value—

Virtus Investment Advisers, LLC

N/A

Shares— from 29,827

Change-29,827 (-100%)

Value—

Squarepoint Ops LLC

N/A

Shares— from 29,630

Change-29,630 (-100%)

Value—

Trexquant Investment LP

N/A

Shares— from 28,150

Change-28,150 (-100%)

Value—

Wells Fargo & Company

N/A

Shares— from 28,072

Change-28,072 (-100%)

Value—

Bridgeway Capital Management, LLC

N/A

Shares— from 27,000

Change-27,000 (-100%)

Value—

Quantinno Capital Management LP

N/A

Shares— from 26,901

Change-26,901 (-100%)

Value—

Price T Rowe Associates Inc

N/A

Shares— from 25,606

Change-25,606 (-100%)

Value—

SEI Investments Co

N/A

Shares— from 22,740

Change-22,740 (-100%)

Value—

XTX Topco Ltd

N/A

Shares— from 22,383

Change-22,383 (-100%)

Value—

Invesco Ltd.

N/A

Shares— from 21,429

Change-21,429 (-100%)

Value—

Public Employees Retirement System of Ohio

N/A

Shares— from 20,700

Change-20,700 (-100%)

Value—

MetLife Investment Management, LLC

N/A

Shares— from 20,609

Change-20,609 (-100%)

Value—

Wellington Management Group LLP

N/A

Shares— from 19,400

Change-19,400 (-100%)

Value—

JPMorgan Chase & Co

N/A

Shares— from 16,904

Change-16,904 (-100%)

Value—

Susquehanna International Group, LLP

N/A

Shares— from 15,650

Change-15,650 (-100%)

Value—

Mirae Asset Global Etfs Holdings Ltd.

N/A

Shares— from 14,171

Change-14,171 (-100%)

Value—

Susquehanna Fundamental Investments, LLC

N/A

Shares— from 12,553

Change-12,553 (-100%)

Value—

Royal Bank of Canada

N/A

Shares— from 12,254

Change-12,254 (-100%)

Value—

New York State Common Retirement Fund

N/A

Shares— from 10,826

Change-10,826 (-100%)

Value—

GSA Capital Partners LLP

N/A

Shares— from 10,328

Change-10,328 (-100%)

Value—

Police & Firemen's Retirement System of New Jersey

N/A

Shares— from 9,849

Change-9,849 (-100%)

Value—

BNP Paribas Financial Markets

N/A

Shares— from 5,751

Change-5,751 (-100%)

Value—

Tower Research Capital LLC (TRC)

N/A

Shares— from 4,908

Change-4,908 (-100%)

Value—

Rockefeller Capital Management L.P.

N/A

Shares— from 3,684

Change-3,684 (-100%)

Value—

CAZ Investments LP

N/A

Shares— from 3,500

Change-3,500 (-100%)

Value—

Zurcher Kantonalbank (Zurich Cantonalbank)

N/A

Shares— from 3,025

Change-3,025 (-100%)

Value—

Legal & General Group Plc

N/A

Shares— from 2,987

Change-2,987 (-100%)

Value—

Ameritas Investment Partners, Inc.

N/A

Shares— from 2,793

Change-2,793 (-100%)

Value—

UBS Asset Management Americas LLC

N/A

Shares— from 1,143

Change-1,143 (-100%)

Value—

Allied Private Wealth LLC

N/A

Shares— from 880

Change-880 (-100%)

Value—

California State Teachers Retirement System

N/A

Shares— from 335

Change-335 (-100%)

Value—

Osaic Holdings, Inc.

N/A

Shares— from 225

Change-225 (-100%)

Value—

Arax Advisory Partners

N/A

Shares— from 180

Change-180 (-100%)

Value—

Optiver Holding B.V.

N/A

Shares— from 160

Change-160 (-100%)

Value—

National Bank of Canada

N/A

Shares— from 83

Change-83 (-100%)

Value—

Quarry LP

N/A

Shares— from 31

Change-31 (-100%)

Value—

Rothschild Investment LLC

N/A

Shares— from 22

Change-22 (-100%)

Value—

	Status
Geode Capital Management, LLC	INCREASED	973,710	958,417	+15,293	+2%	$13.9M	$12.2M	-$1.6M	2026-11-06
Dimensional Fund Advisors LP	INCREASED	727,567	694,743	+32,824	+5%	$10.1M	$9.1M	-$906.0K	2026-11-04
China Universal Asset Management Co., Ltd.	INCREASED	112,419	89,940	+22,479	+25%	$1.3M	$1.4M	+$117.3K	2026-10-28
MacKenzie Financial Corp	NEW	110,764	—	+110,764	—	—	$1.4M	—	2026-11-02
Bank of New York Mellon Corp	INCREASED	97,731	92,069	+5,662	+6%	$1.3M	$1.2M	-$103.8K	2026-11-05
Alps Advisors Inc	INCREASED	82,927	63,391	+19,536	+31%	$917.3K	$1.0M	+$125.1K	2026-11-03
Strs Ohio	INCREASED	64,000	50,500	+13,500	+27%	$730.7K	$804.5K	+$73.7K	2026-10-30
Russell Investments Group, Ltd.	DECREASED	50,505	66,859	-16,354	-24%	$967.4K	$634.8K	-$332.6K	2026-11-06
Y-Intercept (Hong Kong) Ltd	INCREASED	32,468	12,910	+19,558	+151%	$186.8K	$408.1K	+$221.3K	2026-10-16
Creative Planning	INCREASED	32,089	15,844	+16,245	+103%	$229.3K	$403.4K	+$174.1K	2026-11-02
Oppenheimer & Co Inc	DECREASED	31,646	32,087	-441	-1%	$464.3K	$397.8K	-$66.5K	2026-10-26
Deutsche Bank Ag\	DECREASED	26,799	30,613	-3,814	-12%	$443.0K	$336.9K	-$106.1K	2026-11-06
AlphaCentric Advisors LLC	INCREASED	22,505	21,537	+968	+4%	$311.6K	$282.9K	-$28.8K	2026-11-03
Citigroup Inc	INCREASED	19,638	15,880	+3,758	+24%	$229.8K	$246.8K	+$17.1K	2026-11-04
Profund Advisors LLC	NEW	14,351	—	+14,351	—	—	$180.4K	—	2026-10-29
Barclays PLC	INCREASED	11,771	11,707	+64	+1%	$169.4K	$148.0K	-$21.4K	2026-11-06
Clearstead Advisors, LLC	INCREASED	5,611	5,610	+1	+0%	$81.2K	$70.5K	-$10.6K	2026-11-06
Caitong International Asset Management Co., Ltd	INCREASED	4,092	1,259	+2,833	+225%	$18.2K	$51.4K	+$33.2K	2026-10-29
Mirae Asset Global Investments Co., Ltd.	INCREASED	3,198	2,793	+405	+15%	$40.4K	$40.2K	-$216	2026-11-03
Nisa Investment Advisors, LLC	DECREASED	3,124	14,824	-11,700	-79%	$214.5K	$39.3K	-$175.2K	2026-10-20
Gamma Investing LLC	INCREASED	2,135	1,450	+685	+47%	$21.0K	$26.8K	+$5.9K	2026-10-08
State of Wyoming	DECREASED	1,754	2,566	-812	-32%	$37.1K	$22.0K	-$15.1K	2026-10-28
PNC Financial Services Group, Inc.	DECREASED	1,689	1,816	-127	-7%	$26.3K	$21.2K	-$5.0K	2026-11-06
GF Fund Management Co. Ltd.	INCREASED	1,315	1,209	+106	+9%	$17.5K	$16.5K	-$964	2026-10-26
Sterling Capital Management LLC	INCREASED	1,009	108	+901	+834%	$1.6K	$12.7K	+$11.1K	2026-10-22
Larson Financial Group LLC	INCREASED	642	181	+461	+255%	$2.6K	$8.1K	+$5.5K	2026-11-05
EverSource Wealth Advisors, LLC	INCREASED	603	25	+578	+2312%	$362	$7.6K	+$7.2K	2026-11-04
Private Wealth Management Group, LLC	DECREASED	421	533	-112	-21%	$7.7K	$5.3K	-$2.4K	2026-10-19
SJS Investment Consulting Inc.	INCREASED	272	4	+268	+6700%	$58	$3.4K	+$3.4K	2026-10-26
Physician Wealth Advisors, Inc.	UNCHANGED	268	268	0	0%	$3.9K	$3.4K	-$509	2026-10-20
Allworth Financial LP	UNCHANGED	96	96	0	0%	$1.4K	$1.4K	$0	2026-11-06
Versant Capital Management, Inc	UNCHANGED	86	86	0	0%	$1.2K	$1.1K	-$163	2026-10-02
Parkside Financial Bank & Trust	NEW	70	—	+70	—	—	$880	—	2026-10-27
Simplex Trading, LLC	DECREASED	47	172	-125	-73%	$2.5K	$590	-$1.9K	2026-11-04
Farther Finance Advisors, LLC	INCREASED	38	20	+18	+90%	$289	$478	+$189	2026-10-08
Silver Grove Financial Group, Inc.	DECREASED	36	58	-22	-38%	$839	$453	-$386	2026-11-05
Root Financial Partners, LLC	NEW	35	—	+35	—	—	$440	—	2026-10-21
US Bancorp \de\	UNCHANGED	26	26	0	0%	$376	$327	-$49	2026-11-05
True Wealth Design, LLC	INCREASED	23	18	+5	+28%	$261	$290	+$29	2026-10-13
Capital Advisors, Ltd. LLC	UNCHANGED	12	12	0	0%	$0	$0	$0	2026-10-27
SBI Securities Co., Ltd.	UNCHANGED	10	10	0	0%	$145	$126	-$19	2026-10-22
Essential Partners LLC	UNCHANGED	1	1	0	0%	$14	$13	-$1	2026-10-14
MassMutual Private Wealth & Trust, FSB	CLOSED	0	239	-239	-100%	$3.5K	$0	-$3.5K	2026-10-05
Stone House Investment Management, LLC	CLOSED	0	239	-239	-100%	$3.5K	$0	-$3.5K	2026-10-23
SR One Capital Management, LP	N/A	—	6,526,476	-6,526,476	-100%	$94.4M	—	—	—
Logos Global Management LP	N/A	—	3,000,000	-3,000,000	-100%	$43.4M	—	—	—
Baker Bros. Advisors LP	N/A	—	2,678,430	-2,678,430	-100%	$38.8M	—	—	—
Driehaus Capital Management LLC	N/A	—	2,661,115	-2,661,115	-100%	$38.5M	—	—	—
BlackRock, Inc.	N/A	—	2,660,024	-2,660,024	-100%	$38.5M	—	—	—
Point72 Asset Management, L.P.	N/A	—	2,366,453	-2,366,453	-100%	$34.2M	—	—	—
Trails Edge Capital Partners, LP	N/A	—	2,001,282	-2,001,282	-100%	$29.0M	—	—	—
Frazier Life Sciences Management, L.P.	N/A	—	1,809,854	-1,809,854	-100%	$26.2M	—	—	—
Vivo Capital, LLC	N/A	—	1,612,903	-1,612,903	-100%	$23.3M	—	—	—
Vanguard Capital Management LLC	N/A	—	1,571,022	-1,571,022	-100%	$22.7M	—	—	—
Caption Management, LLC	N/A	—	1,118,098	-1,118,098	-100%	$16.2M	—	—	—
Almitas Capital LLC	N/A	—	1,026,893	-1,026,893	-100%	$14.9M	—	—	—
Sofinnova Investments, Inc.	N/A	—	865,135	-865,135	-100%	$12.5M	—	—	—
FMR LLC	N/A	—	776,462	-776,462	-100%	$11.2M	—	—	—
Morgan Stanley	N/A	—	765,425	-765,425	-100%	$11.1M	—	—	—
State Street Corp	N/A	—	736,221	-736,221	-100%	$10.7M	—	—	—
Woodline Partners LP	N/A	—	700,354	-700,354	-100%	$10.1M	—	—	—
Goldman Sachs Group Inc	N/A	—	656,584	-656,584	-100%	$9.5M	—	—	—
Jacobs Levy Equity Management, Inc	N/A	—	565,597	-565,597	-100%	$8.2M	—	—	—
Acadian Asset Management LLC	N/A	—	537,479	-537,479	-100%	$7.8M	—	—	—
Siren, L.L.C.	N/A	—	523,212	-523,212	-100%	$7.6M	—	—	—
Qube Research & Technologies Ltd	N/A	—	437,079	-437,079	-100%	$6.3M	—	—	—
Renaissance Technologies LLC	N/A	—	387,913	-387,913	-100%	$5.6M	—	—	—
Kennedy Capital Management LLC	N/A	—	384,036	-384,036	-100%	$5.6M	—	—	—
Northern Trust Corp	N/A	—	353,197	-353,197	-100%	$5.1M	—	—	—
Algert Global LLC	N/A	—	296,085	-296,085	-100%	$4.3M	—	—	—
Acuta Capital Partners, LLC	N/A	—	282,564	-282,564	-100%	$4.1M	—	—	—
Charles Schwab Investment Management Inc	N/A	—	271,264	-271,264	-100%	$3.9M	—	—	—
Vanguard Portfolio Management LLC	N/A	—	251,442	-251,442	-100%	$3.6M	—	—	—
Vanguard Fiduciary Trust Co	N/A	—	230,202	-230,202	-100%	$3.3M	—	—	—
Prudential Financial Inc	N/A	—	224,170	-224,170	-100%	$3.2M	—	—	—
D. E. Shaw & Co., Inc.	N/A	—	195,645	-195,645	-100%	$2.8M	—	—	—
Eversept Partners, LP	N/A	—	190,000	-190,000	-100%	$2.7M	—	—	—
KVP Capital Advisors, LP	N/A	—	185,000	-185,000	-100%	$2.7M	—	—	—
J. Goldman & Co LP	N/A	—	176,770	-176,770	-100%	$2.6M	—	—	—
Millennium Management LLC	N/A	—	147,714	-147,714	-100%	$2.1M	—	—	—
Raymond James Financial Inc	N/A	—	138,521	-138,521	-100%	$2.0M	—	—	—
Balyasny Asset Management L.P.	N/A	—	111,103	-111,103	-100%	$1.6M	—	—	—
Elmind Capital, LP	N/A	—	107,900	-107,900	-100%	$1.6M	—	—	—
Nuveen, LLC	N/A	—	104,734	-104,734	-100%	$1.5M	—	—	—
Dafna Capital Management LLC	N/A	—	102,600	-102,600	-100%	$1.5M	—	—	—
Citadel Advisors LLC	N/A	—	81,971	-81,971	-100%	$1.2M	—	—	—
SummitTX Capital, L.P.	N/A	—	80,663	-80,663	-100%	$1.2M	—	—	—
American Century Companies Inc	N/A	—	76,825	-76,825	-100%	$1.1M	—	—	—
Palumbo Wealth Management LLC	N/A	—	71,744	-71,744	-100%	$1.0M	—	—	—
AQR Capital Management LLC	N/A	—	71,114	-71,114	-100%	$1.0M	—	—	—
Ameriprise Financial Inc	N/A	—	67,598	-67,598	-100%	$978.1K	—	—	—
State of Wisconsin Investment Board	N/A	—	59,249	-59,249	-100%	$857.3K	—	—	—
Verdad Advisers, LP	N/A	—	47,557	-47,557	-100%	$688.2K	—	—	—
Bank of America Corp	N/A	—	43,728	-43,728	-100%	$632.7K	—	—	—
Alliancebernstein L.P.	N/A	—	43,230	-43,230	-100%	$460.0K	—	—	—
ExodusPoint Capital Management, LP	N/A	—	41,286	-41,286	-100%	$597.4K	—	—	—
Rhumbline Advisers	N/A	—	38,132	-38,132	-100%	$551.8K	—	—	—
Vanguard Global Advisers, LLC	N/A	—	35,534	-35,534	-100%	$514.2K	—	—	—
UBS Group AG	N/A	—	34,761	-34,761	-100%	$503.0K	—	—	—
Susquehanna Portfolio Strategies, LLC	N/A	—	33,375	-33,375	-100%	$482.9K	—	—	—
Two Sigma Investments, LP	N/A	—	32,925	-32,925	-100%	$476.4K	—	—	—
Canada Pension Plan Investment Board	N/A	—	32,600	-32,600	-100%	$471.7K	—	—	—
Virtus Investment Advisers, LLC	N/A	—	29,827	-29,827	-100%	$431.6K	—	—	—
Squarepoint Ops LLC	N/A	—	29,630	-29,630	-100%	$428.7K	—	—	—
Trexquant Investment LP	N/A	—	28,150	-28,150	-100%	$407.3K	—	—	—
Wells Fargo & Company	N/A	—	28,072	-28,072	-100%	$406.2K	—	—	—
Bridgeway Capital Management, LLC	N/A	—	27,000	-27,000	-100%	$390.7K	—	—	—
Quantinno Capital Management LP	N/A	—	26,901	-26,901	-100%	$389.3K	—	—	—
Price T Rowe Associates Inc	N/A	—	25,606	-25,606	-100%	$371.0K	—	—	—
SEI Investments Co	N/A	—	22,740	-22,740	-100%	$329.1K	—	—	—
XTX Topco Ltd	N/A	—	22,383	-22,383	-100%	$323.9K	—	—	—
Invesco Ltd.	N/A	—	21,429	-21,429	-100%	$310.1K	—	—	—
Public Employees Retirement System of Ohio	N/A	—	20,700	-20,700	-100%	$299.5K	—	—	—
MetLife Investment Management, LLC	N/A	—	20,609	-20,609	-100%	$298.2K	—	—	—
Wellington Management Group LLP	N/A	—	19,400	-19,400	-100%	$280.7K	—	—	—
JPMorgan Chase & Co	N/A	—	16,904	-16,904	-100%	$240.7K	—	—	—
Susquehanna International Group, LLP	N/A	—	15,650	-15,650	-100%	$226.5K	—	—	—
Mirae Asset Global Etfs Holdings Ltd.	N/A	—	14,171	-14,171	-100%	$205.1K	—	—	—
Susquehanna Fundamental Investments, LLC	N/A	—	12,553	-12,553	-100%	$181.6K	—	—	—
Royal Bank of Canada	N/A	—	12,254	-12,254	-100%	$178.0K	—	—	—
New York State Common Retirement Fund	N/A	—	10,826	-10,826	-100%	$156.7K	—	—	—
GSA Capital Partners LLP	N/A	—	10,328	-10,328	-100%	$149.0K	—	—	—
Police & Firemen's Retirement System of New Jersey	N/A	—	9,849	-9,849	-100%	$142.5K	—	—	—
BNP Paribas Financial Markets	N/A	—	5,751	-5,751	-100%	$83.2K	—	—	—
Tower Research Capital LLC (TRC)	N/A	—	4,908	-4,908	-100%	$71.0K	—	—	—
Rockefeller Capital Management L.P.	N/A	—	3,684	-3,684	-100%	$53.3K	—	—	—
CAZ Investments LP	N/A	—	3,500	-3,500	-100%	$50.6K	—	—	—
Zurcher Kantonalbank (Zurich Cantonalbank)	N/A	—	3,025	-3,025	-100%	$43.8K	—	—	—
Legal & General Group Plc	N/A	—	2,987	-2,987	-100%	$43.2K	—	—	—
Ameritas Investment Partners, Inc.	N/A	—	2,793	-2,793	-100%	$40.4K	—	—	—
UBS Asset Management Americas LLC	N/A	—	1,143	-1,143	-100%	$16.5K	—	—	—
Allied Private Wealth LLC	N/A	—	880	-880	-100%	$13.4K	—	—	—
California State Teachers Retirement System	N/A	—	335	-335	-100%	$4.8K	—	—	—
Osaic Holdings, Inc.	N/A	—	225	-225	-100%	$3.3K	—	—	—
Arax Advisory Partners	N/A	—	180	-180	-100%	$2.6K	—	—	—
Optiver Holding B.V.	N/A	—	160	-160	-100%	$2.3K	—	—	—
National Bank of Canada	N/A	—	83	-83	-100%	$1.2K	—	—	—
Quarry LP	N/A	—	31	-31	-100%	$449	—	—	—
Rothschild Investment LLC	N/A	—	22	-22	-100%	$318	—	—	—

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