Lyra Therapeutics Inc (LYRA)

Q1 2025 vs Q2 2025

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options Short Interest 13D/13G Peers Targeting Trading Summary Profile

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IFP Advisors, Inc

NEW

Shares300

Change+300

Value$26

Filed 2025-07-24

Perceptive Advisors LLC

CLOSED

Shares0 from 12,757,562

Change-12,757,562 (-100%)

Value$0 (-$1.6M)

Filed 2025-08-14

BlackRock, Inc.

CLOSED

Shares0 from 3,018,986

Change-3,018,986 (-100%)

Value$0 (-$381.3K)

Filed 2025-08-12

Vanguard Group Inc

CLOSED

Shares0 from 1,765,585

Change-1,765,585 (-100%)

Value$0 (-$222.5K)

Filed 2025-08-11

Samsara BioCapital, LLC

CLOSED

Shares0 from 1,390,130

Change-1,390,130 (-100%)

Value$0 (-$175.6K)

Filed 2025-08-14

Ikarian Capital, LLC

CLOSED

Shares0 from 1,058,148

Change-1,058,148 (-100%)

Value$0 (-$133.6K)

Filed 2025-08-14

Geode Capital Management, LLC

CLOSED

Shares0 from 1,016,004

Change-1,016,004 (-100%)

Value$0 (-$128.3K)

Filed 2025-08-08

Adar1 Capital Management, LLC

CLOSED

Shares0 from 533,200

Change-533,200 (-100%)

Value$0 (-$67.3K)

Filed 2025-08-14

State Street Corp

CLOSED

Shares0 from 488,720

Change-488,720 (-100%)

Value$0 (-$61.7K)

Filed 2025-08-14

UBS Group AG

CLOSED

Shares0 from 434,226

Change-434,226 (-100%)

Value$0 (-$54.7K)

Filed 2025-08-14

Goldman Sachs Group Inc

CLOSED

Shares0 from 370,194

Change-370,194 (-100%)

Value$0 (-$46.8K)

Filed 2025-08-14

Two Sigma Advisers, LP

CLOSED

Shares0 from 364,478

Change-364,478 (-100%)

Value$0 (-$46.0K)

Filed 2025-08-14

Northern Trust Corp

CLOSED

Shares0 from 332,639

Change-332,639 (-100%)

Value$0 (-$42.0K)

Filed 2025-08-13

BNP Paribas Financial Markets

CLOSED

Shares0 from 242,546

Change-242,546 (-100%)

Value$0 (-$30.6K)

Filed 2025-08-14

Boothbay Fund Management, LLC

CLOSED

Shares0 from 233,989

Change-233,989 (-100%)

Value$0 (-$29.6K)

Filed 2025-08-14

Susquehanna International Group, LLP

CLOSED

Shares0 from 217,567

Change-217,567 (-100%)

Value$0 (-$27.5K)

Filed 2025-08-14

Two Sigma Investments, LP

CLOSED

Shares0 from 193,145

Change-193,145 (-100%)

Value$0 (-$24.4K)

Filed 2025-08-14

New York State Common Retirement Fund

CLOSED

Shares0 from 154,800

Change-154,800 (-100%)

Value$0 (-$19.6K)

Filed 2025-10-08

Charles Schwab Investment Management Inc

CLOSED

Shares0 from 111,609

Change-111,609 (-100%)

Value$0 (-$14.1K)

Filed 2025-08-12

Rhumbline Advisers

CLOSED

Shares0 from 87,710

Change-87,710 (-100%)

Value$0 (-$11.0K)

Filed 2025-08-12

Bank of New York Mellon Corp

CLOSED

Shares0 from 71,585

Change-71,585 (-100%)

Value$0 (-$9.0K)

Filed 2025-08-05

Morgan Stanley

CLOSED

Shares0 from 65,619

Change-65,619 (-100%)

Value$0 (-$8.3K)

Filed 2025-08-14

FMR LLC

CLOSED

Shares0 from 58,213

Change-58,213 (-100%)

Value$0 (-$7.4K)

Filed 2025-08-14

AQR Capital Management LLC

CLOSED

Shares0 from 58,041

Change-58,041 (-100%)

Value$0 (-$7.3K)

Filed 2025-08-14

JPMorgan Chase & Co

CLOSED

Shares0 from 56,277

Change-56,277 (-100%)

Value$0 (-$7.1K)

Filed 2025-08-12

Tower Research Capital LLC (TRC)

CLOSED

Shares0 from 52,736

Change-52,736 (-100%)

Value$0 (-$6.7K)

Filed 2025-08-15

Barclays PLC

CLOSED

Shares0 from 50,038

Change-50,038 (-100%)

Value$0 (-$6.3K)

Filed 2026-02-27

Jane Street Group, LLC

CLOSED

Shares0 from 43,997

Change-43,997 (-100%)

Value$0 (-$5.6K)

Filed 2025-08-14

Citigroup Inc

CLOSED

Shares0 from 35,177

Change-35,177 (-100%)

Value$0 (-$4.4K)

Filed 2025-08-11

Alliancebernstein L.P.

CLOSED

Shares0 from 33,120

Change-33,120 (-100%)

Value$0 (-$4.2K)

Filed 2025-08-14

SEI Investments Co

CLOSED

Shares0 from 30,067

Change-30,067 (-100%)

Value$0 (-$3.8K)

Filed 2025-08-14

Mirae Asset Global Etfs Holdings Ltd.

CLOSED

Shares0 from 29,018

Change-29,018 (-100%)

Value$0 (-$3.7K)

Filed 2025-08-14

Wells Fargo & Company

CLOSED

Shares0 from 25,305

Change-25,305 (-100%)

Value$0 (-$3.2K)

Filed 2025-08-14

Corebridge Financial, Inc.

CLOSED

Shares0 from 23,709

Change-23,709 (-100%)

Value$0 (-$3.0K)

Filed 2025-08-12

Invesco Ltd.

CLOSED

Shares0 from 23,626

Change-23,626 (-100%)

Value$0 (-$3.0K)

Filed 2025-08-13

Bank of America Corp

CLOSED

Shares0 from 21,352

Change-21,352 (-100%)

Value$0 (-$2.7K)

Filed 2025-08-14

Price T Rowe Associates Inc

CLOSED

Shares0 from 17,541

Change-17,541 (-100%)

Value$0 (-$3)

Filed 2025-08-14

Intech Investment Management LLC

CLOSED

Shares0 from 16,560

Change-16,560 (-100%)

Value$0 (-$2.1K)

Filed 2025-08-08

Squarepoint Ops LLC

CLOSED

Shares0 from 15,283

Change-15,283 (-100%)

Value$0 (-$1.9K)

Filed 2025-08-27

SG Americas Securities, LLC

CLOSED

Shares0 from 14,620

Change-14,620 (-100%)

Value$0 (-$2)

Filed 2025-08-08

Abel Hall, LLC

CLOSED

Shares0 from 12,214

Change-12,214 (-100%)

Value$0 (-$1.5K)

Filed 2025-07-23

CIBC World Markets Corp

CLOSED

Shares0 from 10,739

Change-10,739 (-100%)

Value$0 (-$1.4K)

Filed 2025-08-14

ProShare Advisors LLC

CLOSED

Shares0 from 10,477

Change-10,477 (-100%)

Value$0 (-$1.3K)

Filed 2025-08-07

Sassicaia Capital Advisers LLC

CLOSED

Shares0 from 10,000

Change-10,000 (-100%)

Value$0 (-$1.3K)

Filed 2025-08-13

Royal Bank of Canada

CLOSED

Shares0 from 8,019

Change-8,019 (-100%)

Value$0 (-$1.0K)

Filed 2025-11-21

CWM, LLC

CLOSED

Shares0 from 6,677

Change-6,677 (-100%)

Value$0 (-$1)

Filed 2025-07-25

Northwestern Mutual Wealth Management Co

CLOSED

Shares0 from 6,000

Change-6,000 (-100%)

Value$0 (-$758)

Filed 2025-08-13

Ameritas Investment Partners, Inc.

CLOSED

Shares0 from 4,741

Change-4,741 (-100%)

Value$0 (-$599)

Filed 2025-08-12

SBI Securities Co., Ltd.

CLOSED

Shares0 from 4,272

Change-4,272 (-100%)

Value$0 (-$540)

Filed 2025-08-08

California State Teachers Retirement System

CLOSED

Shares0 from 3,507

Change-3,507 (-100%)

Value$0 (-$443)

Filed 2025-08-14

Amalgamated Bank

CLOSED

Shares0 from 1,674

Change-1,674 (-100%)

Value$0 ($0)

Filed 2025-08-04

Simplex Trading, LLC

CLOSED

Shares0 from 1,317

Change-1,317 (-100%)

Value$0 ($0)

Filed 2025-08-05

Comerica Bank

CLOSED

Shares0 from 1,159

Change-1,159 (-100%)

Value$0 (-$146)

Filed 2025-08-14

Wilmington Savings Fund Society, FSB

CLOSED

Shares0 from 1,025

Change-1,025 (-100%)

Value$0 (-$129)

Filed 2025-07-28

Jones Financial Companies Lllp

CLOSED

Shares0 from 500

Change-500 (-100%)

Value$0 (-$69)

Filed 2025-08-13

Nisa Investment Advisors, LLC

CLOSED

Shares0 from 500

Change-500 (-100%)

Value$0 (-$63)

Filed 2025-07-31

EverSource Wealth Advisors, LLC

CLOSED

Shares0 from 343

Change-343 (-100%)

Value$0 (-$43)

Filed 2025-08-13

Sterling Capital Management LLC

CLOSED

Shares0 from 88

Change-88 (-100%)

Value$0 (-$11)

Filed 2025-08-08

Proequities, Inc.

CLOSED

Shares0 from 0

Change0

Value$0 ($0)

Filed 2025-08-12

	Status
IFP Advisors, Inc	NEW	300	—	+300	—	—	$26	—	2025-07-24
Perceptive Advisors LLC	CLOSED	0	12,757,562	-12,757,562	-100%	$1.6M	$0	-$1.6M	2025-08-14
BlackRock, Inc.	CLOSED	0	3,018,986	-3,018,986	-100%	$381.3K	$0	-$381.3K	2025-08-12
Vanguard Group Inc	CLOSED	0	1,765,585	-1,765,585	-100%	$222.5K	$0	-$222.5K	2025-08-11
Samsara BioCapital, LLC	CLOSED	0	1,390,130	-1,390,130	-100%	$175.6K	$0	-$175.6K	2025-08-14
Ikarian Capital, LLC	CLOSED	0	1,058,148	-1,058,148	-100%	$133.6K	$0	-$133.6K	2025-08-14
Geode Capital Management, LLC	CLOSED	0	1,016,004	-1,016,004	-100%	$128.3K	$0	-$128.3K	2025-08-08
Adar1 Capital Management, LLC	CLOSED	0	533,200	-533,200	-100%	$67.3K	$0	-$67.3K	2025-08-14
State Street Corp	CLOSED	0	488,720	-488,720	-100%	$61.7K	$0	-$61.7K	2025-08-14
UBS Group AG	CLOSED	0	434,226	-434,226	-100%	$54.7K	$0	-$54.7K	2025-08-14
Goldman Sachs Group Inc	CLOSED	0	370,194	-370,194	-100%	$46.8K	$0	-$46.8K	2025-08-14
Two Sigma Advisers, LP	CLOSED	0	364,478	-364,478	-100%	$46.0K	$0	-$46.0K	2025-08-14
Northern Trust Corp	CLOSED	0	332,639	-332,639	-100%	$42.0K	$0	-$42.0K	2025-08-13
BNP Paribas Financial Markets	CLOSED	0	242,546	-242,546	-100%	$30.6K	$0	-$30.6K	2025-08-14
Boothbay Fund Management, LLC	CLOSED	0	233,989	-233,989	-100%	$29.6K	$0	-$29.6K	2025-08-14
Susquehanna International Group, LLP	CLOSED	0	217,567	-217,567	-100%	$27.5K	$0	-$27.5K	2025-08-14
Two Sigma Investments, LP	CLOSED	0	193,145	-193,145	-100%	$24.4K	$0	-$24.4K	2025-08-14
New York State Common Retirement Fund	CLOSED	0	154,800	-154,800	-100%	$19.6K	$0	-$19.6K	2025-10-08
Charles Schwab Investment Management Inc	CLOSED	0	111,609	-111,609	-100%	$14.1K	$0	-$14.1K	2025-08-12
Rhumbline Advisers	CLOSED	0	87,710	-87,710	-100%	$11.0K	$0	-$11.0K	2025-08-12
Bank of New York Mellon Corp	CLOSED	0	71,585	-71,585	-100%	$9.0K	$0	-$9.0K	2025-08-05
Morgan Stanley	CLOSED	0	65,619	-65,619	-100%	$8.3K	$0	-$8.3K	2025-08-14
FMR LLC	CLOSED	0	58,213	-58,213	-100%	$7.4K	$0	-$7.4K	2025-08-14
AQR Capital Management LLC	CLOSED	0	58,041	-58,041	-100%	$7.3K	$0	-$7.3K	2025-08-14
JPMorgan Chase & Co	CLOSED	0	56,277	-56,277	-100%	$7.1K	$0	-$7.1K	2025-08-12
Tower Research Capital LLC (TRC)	CLOSED	0	52,736	-52,736	-100%	$6.7K	$0	-$6.7K	2025-08-15
Barclays PLC	CLOSED	0	50,038	-50,038	-100%	$6.3K	$0	-$6.3K	2026-02-27
Jane Street Group, LLC	CLOSED	0	43,997	-43,997	-100%	$5.6K	$0	-$5.6K	2025-08-14
Citigroup Inc	CLOSED	0	35,177	-35,177	-100%	$4.4K	$0	-$4.4K	2025-08-11
Alliancebernstein L.P.	CLOSED	0	33,120	-33,120	-100%	$4.2K	$0	-$4.2K	2025-08-14
SEI Investments Co	CLOSED	0	30,067	-30,067	-100%	$3.8K	$0	-$3.8K	2025-08-14
Mirae Asset Global Etfs Holdings Ltd.	CLOSED	0	29,018	-29,018	-100%	$3.7K	$0	-$3.7K	2025-08-14
Wells Fargo & Company	CLOSED	0	25,305	-25,305	-100%	$3.2K	$0	-$3.2K	2025-08-14
Corebridge Financial, Inc.	CLOSED	0	23,709	-23,709	-100%	$3.0K	$0	-$3.0K	2025-08-12
Invesco Ltd.	CLOSED	0	23,626	-23,626	-100%	$3.0K	$0	-$3.0K	2025-08-13
Bank of America Corp	CLOSED	0	21,352	-21,352	-100%	$2.7K	$0	-$2.7K	2025-08-14
Price T Rowe Associates Inc	CLOSED	0	17,541	-17,541	-100%	$3	$0	-$3	2025-08-14
Intech Investment Management LLC	CLOSED	0	16,560	-16,560	-100%	$2.1K	$0	-$2.1K	2025-08-08
Squarepoint Ops LLC	CLOSED	0	15,283	-15,283	-100%	$1.9K	$0	-$1.9K	2025-08-27
SG Americas Securities, LLC	CLOSED	0	14,620	-14,620	-100%	$2	$0	-$2	2025-08-08
Abel Hall, LLC	CLOSED	0	12,214	-12,214	-100%	$1.5K	$0	-$1.5K	2025-07-23
CIBC World Markets Corp	CLOSED	0	10,739	-10,739	-100%	$1.4K	$0	-$1.4K	2025-08-14
ProShare Advisors LLC	CLOSED	0	10,477	-10,477	-100%	$1.3K	$0	-$1.3K	2025-08-07
Sassicaia Capital Advisers LLC	CLOSED	0	10,000	-10,000	-100%	$1.3K	$0	-$1.3K	2025-08-13
Royal Bank of Canada	CLOSED	0	8,019	-8,019	-100%	$1.0K	$0	-$1.0K	2025-11-21
CWM, LLC	CLOSED	0	6,677	-6,677	-100%	$1	$0	-$1	2025-07-25
Northwestern Mutual Wealth Management Co	CLOSED	0	6,000	-6,000	-100%	$758	$0	-$758	2025-08-13
Ameritas Investment Partners, Inc.	CLOSED	0	4,741	-4,741	-100%	$599	$0	-$599	2025-08-12
SBI Securities Co., Ltd.	CLOSED	0	4,272	-4,272	-100%	$540	$0	-$540	2025-08-08
California State Teachers Retirement System	CLOSED	0	3,507	-3,507	-100%	$443	$0	-$443	2025-08-14
Amalgamated Bank	CLOSED	0	1,674	-1,674	-100%	$0	$0	$0	2025-08-04
Simplex Trading, LLC	CLOSED	0	1,317	-1,317	-100%	$0	$0	$0	2025-08-05
Comerica Bank	CLOSED	0	1,159	-1,159	-100%	$146	$0	-$146	2025-08-14
Wilmington Savings Fund Society, FSB	CLOSED	0	1,025	-1,025	-100%	$129	$0	-$129	2025-07-28
Jones Financial Companies Lllp	CLOSED	0	500	-500	-100%	$69	$0	-$69	2025-08-13
Nisa Investment Advisors, LLC	CLOSED	0	500	-500	-100%	$63	$0	-$63	2025-07-31
EverSource Wealth Advisors, LLC	CLOSED	0	343	-343	-100%	$43	$0	-$43	2025-08-13
Sterling Capital Management LLC	CLOSED	0	88	-88	-100%	$11	$0	-$11	2025-08-08
Proequities, Inc.	CLOSED	0	0	0	—	$0	$0	$0	2025-08-12

Showing 59 of 59 institutions