Prelude Therapeutics Inc (PRLD)

Q2 2026 vs Q3 2026

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options 13D/13G Peers Targeting Trading Summary Profile

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Dimensional Fund Advisors LP

INCREASED

Shares89,041 from 35,210

Change+53,831 (+153%)

Value$348.5K (+$161.7K)

Filed 2026-11-04

Bank of New York Mellon Corp

UNCHANGED

Shares68,187 from 68,187

Change0 (0%)

Value$266.6K (-$96.8K)

Filed 2026-11-05

Empirical Financial Services, LLC d.b.a. Empirical Wealth Management

NEW

Shares12,841

Change+12,841

Value$50.2K

Filed 2026-10-27

Strs Ohio

INCREASED

Shares7,700 from 5,500

Change+2,200 (+40%)

Value$30.1K (+$792)

Filed 2026-10-30

State of Wyoming

DECREASED

Shares6,629 from 32,862

Change-26,233 (-80%)

Value$25.9K (-$149.2K)

Filed 2026-10-28

Nisa Investment Advisors, LLC

UNCHANGED

Shares1,634 from 1,634

Change0 (0%)

Value$6.4K (-$2.3K)

Filed 2026-10-20

Citigroup Inc

DECREASED

Shares1,376 from 13,033

Change-11,657 (-89%)

Value$5.4K (-$64.1K)

Filed 2026-11-04

Sterling Capital Management LLC

INCREASED

Shares911 from 97

Change+814 (+839%)

Value$3.6K (+$3.0K)

Filed 2026-10-22

Gamma Investing LLC

NEW

Shares495

Change+495

Value$1.9K

Filed 2026-10-08

Fortitude Family Office, LLC

UNCHANGED

Shares230 from 230

Change0 (0%)

Value$899 (-$327)

Filed 2026-10-14

Farther Finance Advisors, LLC

NEW

Shares44

Change+44

Value$172

Filed 2026-10-08

SBI Securities Co., Ltd.

INCREASED

Shares27 from 22

Change+5 (+23%)

Value$106 (-$11)

Filed 2026-10-22

Caitong International Asset Management Co., Ltd

DECREASED

Shares5 from 18

Change-13 (-72%)

Value$20 (-$76)

Filed 2026-10-29

Orbimed Advisors LLC

N/A

Shares— from 13,724,571

Change-13,724,571 (-100%)

Value—

Baker Bros. Advisors LP

N/A

Shares— from 10,123,824

Change-10,123,824 (-100%)

Value—

RA Capital Management, L.P.

N/A

Shares— from 6,475,882

Change-6,475,882 (-100%)

Value—

Soleus Capital Management, L.P.

N/A

Shares— from 3,378,378

Change-3,378,378 (-100%)

Value—

Kynam Capital Management, LP

N/A

Shares— from 2,415,087

Change-2,415,087 (-100%)

Value—

Vanguard Capital Management LLC

N/A

Shares— from 2,009,445

Change-2,009,445 (-100%)

Value—

BlackRock, Inc.

N/A

Shares— from 1,797,501

Change-1,797,501 (-100%)

Value—

Sphera Funds Management Ltd.

N/A

Shares— from 1,019,832

Change-1,019,832 (-100%)

Value—

Two Sigma Investments, LP

N/A

Shares— from 993,369

Change-993,369 (-100%)

Value—

Adar1 Capital Management, LLC

N/A

Shares— from 900,900

Change-900,900 (-100%)

Value—

Millennium Management LLC

N/A

Shares— from 844,993

Change-844,993 (-100%)

Value—

Geode Capital Management, LLC

N/A

Shares— from 841,862

Change-841,862 (-100%)

Value—

Adage Capital Partners GP, L.L.C.

N/A

Shares— from 766,095

Change-766,095 (-100%)

Value—

Acadian Asset Management LLC

N/A

Shares— from 611,359

Change-611,359 (-100%)

Value—

Morgan Stanley

N/A

Shares— from 503,860

Change-503,860 (-100%)

Value—

State Street Corp

N/A

Shares— from 428,787

Change-428,787 (-100%)

Value—

UBS Group AG

N/A

Shares— from 318,797

Change-318,797 (-100%)

Value—

Vanguard Fiduciary Trust Co

N/A

Shares— from 284,886

Change-284,886 (-100%)

Value—

Renaissance Technologies LLC

N/A

Shares— from 281,200

Change-281,200 (-100%)

Value—

Northern Trust Corp

N/A

Shares— from 240,599

Change-240,599 (-100%)

Value—

Vanguard Portfolio Management LLC

N/A

Shares— from 193,920

Change-193,920 (-100%)

Value—

Marshall Wace, LLP

N/A

Shares— from 190,692

Change-190,692 (-100%)

Value—

Connor, Clark & Lunn Investment Management Ltd.

N/A

Shares— from 125,606

Change-125,606 (-100%)

Value—

Goldman Sachs Group Inc

N/A

Shares— from 120,834

Change-120,834 (-100%)

Value—

Hillsdale Investment Management Inc.

N/A

Shares— from 81,400

Change-81,400 (-100%)

Value—

Charles Schwab Investment Management Inc

N/A

Shares— from 67,622

Change-67,622 (-100%)

Value—

Bridgeway Capital Management, LLC

N/A

Shares— from 64,500

Change-64,500 (-100%)

Value—

Squarepoint Ops LLC

N/A

Shares— from 59,540

Change-59,540 (-100%)

Value—

Panagora Asset Management Inc

N/A

Shares— from 47,574

Change-47,574 (-100%)

Value—

Mariner, LLC

N/A

Shares— from 45,261

Change-45,261 (-100%)

Value—

Nuveen, LLC

N/A

Shares— from 37,023

Change-37,023 (-100%)

Value—

Invesco Ltd.

N/A

Shares— from 34,742

Change-34,742 (-100%)

Value—

Cerity Partners LLC

N/A

Shares— from 32,875

Change-32,875 (-100%)

Value—

Graham Capital Management, L.P.

N/A

Shares— from 29,770

Change-29,770 (-100%)

Value—

Deutsche Bank Ag\

N/A

Shares— from 27,824

Change-27,824 (-100%)

Value—

Wells Fargo & Company

N/A

Shares— from 25,325

Change-25,325 (-100%)

Value—

Bank of America Corp

N/A

Shares— from 23,875

Change-23,875 (-100%)

Value—

Price T Rowe Associates Inc

N/A

Shares— from 22,758

Change-22,758 (-100%)

Value—

Citadel Advisors LLC

N/A

Shares— from 22,554

Change-22,554 (-100%)

Value—

Rhumbline Advisers

N/A

Shares— from 22,074

Change-22,074 (-100%)

Value—

Vanguard Global Advisers, LLC

N/A

Shares— from 16,210

Change-16,210 (-100%)

Value—

ExodusPoint Capital Management, LP

N/A

Shares— from 15,475

Change-15,475 (-100%)

Value—

Barclays PLC

N/A

Shares— from 14,529

Change-14,529 (-100%)

Value—

New York State Common Retirement Fund

N/A

Shares— from 14,200

Change-14,200 (-100%)

Value—

HSBC Holdings PLC

N/A

Shares— from 13,652

Change-13,652 (-100%)

Value—

JPMorgan Chase & Co

N/A

Shares— from 13,538

Change-13,538 (-100%)

Value—

Mangrove Partners IM, LLC

N/A

Shares— from 13,352

Change-13,352 (-100%)

Value—

Qube Research & Technologies Ltd

N/A

Shares— from 13,110

Change-13,110 (-100%)

Value—

Mirae Asset Global Etfs Holdings Ltd.

N/A

Shares— from 12,784

Change-12,784 (-100%)

Value—

GSA Capital Partners LLP

N/A

Shares— from 12,672

Change-12,672 (-100%)

Value—

Spark Investment Management LLC

N/A

Shares— from 10,600

Change-10,600 (-100%)

Value—

Alliancebernstein L.P.

N/A

Shares— from 10,530

Change-10,530 (-100%)

Value—

Police & Firemen's Retirement System of New Jersey

N/A

Shares— from 10,492

Change-10,492 (-100%)

Value—

LOS Angeles Capital Management LLC

N/A

Shares— from 6,430

Change-6,430 (-100%)

Value—

FMR LLC

N/A

Shares— from 5,629

Change-5,629 (-100%)

Value—

BNP Paribas Financial Markets

N/A

Shares— from 4,104

Change-4,104 (-100%)

Value—

Group One Trading LLC

N/A

Shares— from 3,907

Change-3,907 (-100%)

Value—

Legal & General Group Plc

N/A

Shares— from 2,699

Change-2,699 (-100%)

Value—

Royal Bank of Canada

N/A

Shares— from 2,658

Change-2,658 (-100%)

Value—

Ameritas Investment Partners, Inc.

N/A

Shares— from 2,520

Change-2,520 (-100%)

Value—

Tower Research Capital LLC (TRC)

N/A

Shares— from 2,377

Change-2,377 (-100%)

Value—

Russell Investments Group, Ltd.

N/A

Shares— from 2,220

Change-2,220 (-100%)

Value—

PNC Financial Services Group, Inc.

N/A

Shares— from 1,171

Change-1,171 (-100%)

Value—

Quarry LP

N/A

Shares— from 755

Change-755 (-100%)

Value—

Optiver Holding B.V.

N/A

Shares— from 4

Change-4 (-100%)

Value—

	Status
Dimensional Fund Advisors LP	INCREASED	89,041	35,210	+53,831	+153%	$186.8K	$348.5K	+$161.7K	2026-11-04
Bank of New York Mellon Corp	UNCHANGED	68,187	68,187	0	0%	$363.4K	$266.6K	-$96.8K	2026-11-05
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management	NEW	12,841	—	+12,841	—	—	$50.2K	—	2026-10-27
Strs Ohio	INCREASED	7,700	5,500	+2,200	+40%	$29.3K	$30.1K	+$792	2026-10-30
State of Wyoming	DECREASED	6,629	32,862	-26,233	-80%	$175.2K	$25.9K	-$149.2K	2026-10-28
Nisa Investment Advisors, LLC	UNCHANGED	1,634	1,634	0	0%	$8.7K	$6.4K	-$2.3K	2026-10-20
Citigroup Inc	DECREASED	1,376	13,033	-11,657	-89%	$69.5K	$5.4K	-$64.1K	2026-11-04
Sterling Capital Management LLC	INCREASED	911	97	+814	+839%	$517	$3.6K	+$3.0K	2026-10-22
Gamma Investing LLC	NEW	495	—	+495	—	—	$1.9K	—	2026-10-08
Fortitude Family Office, LLC	UNCHANGED	230	230	0	0%	$1.2K	$899	-$327	2026-10-14
Farther Finance Advisors, LLC	NEW	44	—	+44	—	—	$172	—	2026-10-08
SBI Securities Co., Ltd.	INCREASED	27	22	+5	+23%	$117	$106	-$11	2026-10-22
Caitong International Asset Management Co., Ltd	DECREASED	5	18	-13	-72%	$96	$20	-$76	2026-10-29
Orbimed Advisors LLC	N/A	—	13,724,571	-13,724,571	-100%	$73.2M	—	—	—
Baker Bros. Advisors LP	N/A	—	10,123,824	-10,123,824	-100%	$54.0M	—	—	—
RA Capital Management, L.P.	N/A	—	6,475,882	-6,475,882	-100%	$34.5M	—	—	—
Soleus Capital Management, L.P.	N/A	—	3,378,378	-3,378,378	-100%	$18.0M	—	—	—
Kynam Capital Management, LP	N/A	—	2,415,087	-2,415,087	-100%	$12.9M	—	—	—
Vanguard Capital Management LLC	N/A	—	2,009,445	-2,009,445	-100%	$10.7M	—	—	—
BlackRock, Inc.	N/A	—	1,797,501	-1,797,501	-100%	$9.6M	—	—	—
Sphera Funds Management Ltd.	N/A	—	1,019,832	-1,019,832	-100%	$5.4M	—	—	—
Two Sigma Investments, LP	N/A	—	993,369	-993,369	-100%	$5.3M	—	—	—
Adar1 Capital Management, LLC	N/A	—	900,900	-900,900	-100%	$4.8M	—	—	—
Millennium Management LLC	N/A	—	844,993	-844,993	-100%	$4.5M	—	—	—
Geode Capital Management, LLC	N/A	—	841,862	-841,862	-100%	$4.5M	—	—	—
Adage Capital Partners GP, L.L.C.	N/A	—	766,095	-766,095	-100%	$4.1M	—	—	—
Acadian Asset Management LLC	N/A	—	611,359	-611,359	-100%	$3.3M	—	—	—
Morgan Stanley	N/A	—	503,860	-503,860	-100%	$2.7M	—	—	—
State Street Corp	N/A	—	428,787	-428,787	-100%	$2.3M	—	—	—
UBS Group AG	N/A	—	318,797	-318,797	-100%	$1.7M	—	—	—
Vanguard Fiduciary Trust Co	N/A	—	284,886	-284,886	-100%	$1.5M	—	—	—
Renaissance Technologies LLC	N/A	—	281,200	-281,200	-100%	$1.5M	—	—	—
Northern Trust Corp	N/A	—	240,599	-240,599	-100%	$1.3M	—	—	—
Vanguard Portfolio Management LLC	N/A	—	193,920	-193,920	-100%	$1.0M	—	—	—
Marshall Wace, LLP	N/A	—	190,692	-190,692	-100%	$1.0M	—	—	—
Connor, Clark & Lunn Investment Management Ltd.	N/A	—	125,606	-125,606	-100%	$669.5K	—	—	—
Goldman Sachs Group Inc	N/A	—	120,834	-120,834	-100%	$644.0K	—	—	—
Hillsdale Investment Management Inc.	N/A	—	81,400	-81,400	-100%	$433.9K	—	—	—
Charles Schwab Investment Management Inc	N/A	—	67,622	-67,622	-100%	$360.4K	—	—	—
Bridgeway Capital Management, LLC	N/A	—	64,500	-64,500	-100%	$343.8K	—	—	—
Squarepoint Ops LLC	N/A	—	59,540	-59,540	-100%	$317.3K	—	—	—
Panagora Asset Management Inc	N/A	—	47,574	-47,574	-100%	$253.6K	—	—	—
Mariner, LLC	N/A	—	45,261	-45,261	-100%	$241.2K	—	—	—
Nuveen, LLC	N/A	—	37,023	-37,023	-100%	$197.3K	—	—	—
Invesco Ltd.	N/A	—	34,742	-34,742	-100%	$185.2K	—	—	—
Cerity Partners LLC	N/A	—	32,875	-32,875	-100%	$175.2K	—	—	—
Graham Capital Management, L.P.	N/A	—	29,770	-29,770	-100%	$158.7K	—	—	—
Deutsche Bank Ag\	N/A	—	27,824	-27,824	-100%	$148.3K	—	—	—
Wells Fargo & Company	N/A	—	25,325	-25,325	-100%	$135.0K	—	—	—
Bank of America Corp	N/A	—	23,875	-23,875	-100%	$127.3K	—	—	—
Price T Rowe Associates Inc	N/A	—	22,758	-22,758	-100%	$122.0K	—	—	—
Citadel Advisors LLC	N/A	—	22,554	-22,554	-100%	$120.2K	—	—	—
Rhumbline Advisers	N/A	—	22,074	-22,074	-100%	$117.6K	—	—	—
Vanguard Global Advisers, LLC	N/A	—	16,210	-16,210	-100%	$86.4K	—	—	—
ExodusPoint Capital Management, LP	N/A	—	15,475	-15,475	-100%	$82.5K	—	—	—
Barclays PLC	N/A	—	14,529	-14,529	-100%	$77.4K	—	—	—
New York State Common Retirement Fund	N/A	—	14,200	-14,200	-100%	$75.7K	—	—	—
HSBC Holdings PLC	N/A	—	13,652	-13,652	-100%	$74.4K	—	—	—
JPMorgan Chase & Co	N/A	—	13,538	-13,538	-100%	$66.7K	—	—	—
Mangrove Partners IM, LLC	N/A	—	13,352	-13,352	-100%	$71.2K	—	—	—
Qube Research & Technologies Ltd	N/A	—	13,110	-13,110	-100%	$69.9K	—	—	—
Mirae Asset Global Etfs Holdings Ltd.	N/A	—	12,784	-12,784	-100%	$68.1K	—	—	—
GSA Capital Partners LLP	N/A	—	12,672	-12,672	-100%	$68.0K	—	—	—
Spark Investment Management LLC	N/A	—	10,600	-10,600	-100%	$56.5K	—	—	—
Alliancebernstein L.P.	N/A	—	10,530	-10,530	-100%	$36.0K	—	—	—
Police & Firemen's Retirement System of New Jersey	N/A	—	10,492	-10,492	-100%	$55.9K	—	—	—
LOS Angeles Capital Management LLC	N/A	—	6,430	-6,430	-100%	$34.3K	—	—	—
FMR LLC	N/A	—	5,629	-5,629	-100%	$30.0K	—	—	—
BNP Paribas Financial Markets	N/A	—	4,104	-4,104	-100%	$21.9K	—	—	—
Group One Trading LLC	N/A	—	3,907	-3,907	-100%	$20.8K	—	—	—
Legal & General Group Plc	N/A	—	2,699	-2,699	-100%	$14.4K	—	—	—
Royal Bank of Canada	N/A	—	2,658	-2,658	-100%	$14.0K	—	—	—
Ameritas Investment Partners, Inc.	N/A	—	2,520	-2,520	-100%	$13.4K	—	—	—
Tower Research Capital LLC (TRC)	N/A	—	2,377	-2,377	-100%	$12.7K	—	—	—
Russell Investments Group, Ltd.	N/A	—	2,220	-2,220	-100%	$11.8K	—	—	—
PNC Financial Services Group, Inc.	N/A	—	1,171	-1,171	-100%	$6.2K	—	—	—
Quarry LP	N/A	—	755	-755	-100%	$4.0K	—	—	—
Optiver Holding B.V.	N/A	—	4	-4	-100%	$21	—	—	—

Showing 78 of 78 institutions