Seaport Therapeutics Inc (SPTX)

Q2 2026 vs Q3 2026

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options Short Interest 13D/13G Peers Targeting Trading Summary Profile

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FMR LLC

INCREASED

Shares1,837,672 from 1,185,100

Change+652,572 (+55%)

Value$37.1M (+$11.3M)

Filed 2026-11-10

Principal Financial Group Inc

DECREASED

Shares377,391 from 414,672

Change-37,281 (-9%)

Value$7.6M (-$1.4M)

Filed 2026-11-02

Geode Capital Management, LLC

INCREASED

Shares377,231 from 175,866

Change+201,365 (+115%)

Value$7.6M (+$3.8M)

Filed 2026-11-06

Aberdeen Group plc

DECREASED

Shares267,678 from 310,355

Change-42,677 (-14%)

Value$35.9M (+$29.1M)

Filed 2026-11-06

AdvisorShares Investments LLC

NEW

Shares94,000

Change+94,000

Value$1.9M

Filed 2026-11-09

Alps Advisors Inc

INCREASED

Shares70,921 from 54,328

Change+16,593 (+31%)

Value$1.4M (+$250.5K)

Filed 2026-11-03

Bank of New York Mellon Corp

NEW

Shares29,489

Change+29,489

Value$594.8K

Filed 2026-11-05

Nuveen, LLC

NEW

Shares18,603

Change+18,603

Value$375.2K

Filed 2026-11-10

HighTower Advisors, LLC

UNCHANGED

Shares16,666 from 16,666

Change0 (0%)

Value$336.2K (-$25.8K)

Filed 2026-11-10

Deutsche Bank Ag\

NEW

Shares12,024

Change+12,024

Value$242.5K

Filed 2026-11-06

Citigroup Inc

INCREASED

Shares6,820 from 2,454

Change+4,366 (+178%)

Value$137.6K (+$84.3K)

Filed 2026-11-04

Barclays PLC

INCREASED

Shares5,600 from 837

Change+4,763 (+569%)

Value$113.0K (+$94.8K)

Filed 2026-11-06

Strs Ohio

NEW

Shares3,800

Change+3,800

Value$76.6K

Filed 2026-10-30

Police & Firemen's Retirement System of New Jersey

NEW

Shares3,342

Change+3,342

Value$67.4K

Filed 2026-11-09

Assetmark, Inc

INCREASED

Shares1,767 from 1,431

Change+336 (+23%)

Value$35.6K (+$4.6K)

Filed 2026-10-21

Russell Investments Group, Ltd.

NEW

Shares1,093

Change+1,093

Value$22.0K

Filed 2026-11-06

Sterling Capital Management LLC

NEW

Shares391

Change+391

Value$7.9K

Filed 2026-10-22

Farther Finance Advisors, LLC

NEW

Shares334

Change+334

Value$6.7K

Filed 2026-10-08

Squarepoint Ops LLC

CLOSED

Shares0 from 24,753

Change-24,753 (-100%)

Value$0 (-$537.6K)

Filed 2026-11-09

Arch Venture Management, LLC

N/A

Shares— from 6,294,951

Change-6,294,951 (-100%)

Value—

General Atlantic, L.P.

N/A

Shares— from 6,101,582

Change-6,101,582 (-100%)

Value—

Sofinnova Investments, Inc.

N/A

Shares— from 3,564,871

Change-3,564,871 (-100%)

Value—

Goldman Sachs Group Inc

N/A

Shares— from 2,178,642

Change-2,178,642 (-100%)

Value—

TRV GP VI, LLC

N/A

Shares— from 2,061,222

Change-2,061,222 (-100%)

Value—

Canada Pension Plan Investment Board

N/A

Shares— from 1,975,791

Change-1,975,791 (-100%)

Value—

JPMorgan Chase & Co

N/A

Shares— from 1,815,845

Change-1,815,845 (-100%)

Value—

Foresite Capital Management VI LLC

N/A

Shares— from 1,779,521

Change-1,779,521 (-100%)

Value—

Price T Rowe Associates Inc

N/A

Shares— from 1,308,604

Change-1,308,604 (-100%)

Value—

Bellevue Group AG

N/A

Shares— from 1,100,000

Change-1,100,000 (-100%)

Value—

Siren, L.L.C.

N/A

Shares— from 1,095,316

Change-1,095,316 (-100%)

Value—

Jennison Associates LLC

N/A

Shares— from 1,079,669

Change-1,079,669 (-100%)

Value—

RA Capital Management, L.P.

N/A

Shares— from 700,000

Change-700,000 (-100%)

Value—

Vanguard Capital Management LLC

N/A

Shares— from 599,217

Change-599,217 (-100%)

Value—

Woodline Partners LP

N/A

Shares— from 586,345

Change-586,345 (-100%)

Value—

Perceptive Advisors LLC

N/A

Shares— from 500,000

Change-500,000 (-100%)

Value—

Braidwell LP

N/A

Shares— from 500,000

Change-500,000 (-100%)

Value—

UBS Group AG

N/A

Shares— from 279,184

Change-279,184 (-100%)

Value—

BlackRock, Inc.

N/A

Shares— from 229,863

Change-229,863 (-100%)

Value—

Seven Grand Managers, LLC

N/A

Shares— from 225,000

Change-225,000 (-100%)

Value—

Citadel Advisors LLC

N/A

Shares— from 191,144

Change-191,144 (-100%)

Value—

Pier Capital, LLC

N/A

Shares— from 169,985

Change-169,985 (-100%)

Value—

Ameriprise Financial Inc

N/A

Shares— from 131,788

Change-131,788 (-100%)

Value—

Charles Schwab Investment Management Inc

N/A

Shares— from 97,693

Change-97,693 (-100%)

Value—

Vanguard Fiduciary Trust Co

N/A

Shares— from 87,772

Change-87,772 (-100%)

Value—

Pentwater Capital Management LP

N/A

Shares— from 83,000

Change-83,000 (-100%)

Value—

Manufacturers Life Insurance Company, the

N/A

Shares— from 82,565

Change-82,565 (-100%)

Value—

Alyeska Investment Group, L.P.

N/A

Shares— from 75,000

Change-75,000 (-100%)

Value—

State Street Corp

N/A

Shares— from 66,650

Change-66,650 (-100%)

Value—

TD Asset Management Inc

N/A

Shares— from 47,944

Change-47,944 (-100%)

Value—

Millennium Management LLC

N/A

Shares— from 45,337

Change-45,337 (-100%)

Value—

GSA Capital Partners LLP

N/A

Shares— from 33,178

Change-33,178 (-100%)

Value—

Dafna Capital Management LLC

N/A

Shares— from 32,400

Change-32,400 (-100%)

Value—

Northern Trust Corp

N/A

Shares— from 31,802

Change-31,802 (-100%)

Value—

Adar1 Capital Management, LLC

N/A

Shares— from 26,000

Change-26,000 (-100%)

Value—

Burkehill Global Management, LP

N/A

Shares— from 25,000

Change-25,000 (-100%)

Value—

Ghisallo Capital Management LLC

N/A

Shares— from 25,000

Change-25,000 (-100%)

Value—

Morgan Stanley

N/A

Shares— from 11,692

Change-11,692 (-100%)

Value—

XTX Topco Ltd

N/A

Shares— from 10,983

Change-10,983 (-100%)

Value—

Weiss Asset Management LP

N/A

Shares— from 10,000

Change-10,000 (-100%)

Value—

Zimmer Partners, LP

N/A

Shares— from 10,000

Change-10,000 (-100%)

Value—

Vanguard Portfolio Management LLC

N/A

Shares— from 9,081

Change-9,081 (-100%)

Value—

Vanguard Global Advisers, LLC

N/A

Shares— from 7,159

Change-7,159 (-100%)

Value—

Jones Financial Companies Lllp

N/A

Shares— from 2,256

Change-2,256 (-100%)

Value—

	Status
FMR LLC	INCREASED	1,837,672	1,185,100	+652,572	+55%	$25.7M	$37.1M	+$11.3M	2026-11-10
Principal Financial Group Inc	DECREASED	377,391	414,672	-37,281	-9%	$9.0M	$7.6M	-$1.4M	2026-11-02
Geode Capital Management, LLC	INCREASED	377,231	175,866	+201,365	+115%	$3.8M	$7.6M	+$3.8M	2026-11-06
Aberdeen Group plc	DECREASED	267,678	310,355	-42,677	-14%	$6.7M	$35.9M	+$29.1M	2026-11-06
AdvisorShares Investments LLC	NEW	94,000	—	+94,000	—	—	$1.9M	—	2026-11-09
Alps Advisors Inc	INCREASED	70,921	54,328	+16,593	+31%	$1.2M	$1.4M	+$250.5K	2026-11-03
Bank of New York Mellon Corp	NEW	29,489	—	+29,489	—	—	$594.8K	—	2026-11-05
Nuveen, LLC	NEW	18,603	—	+18,603	—	—	$375.2K	—	2026-11-10
HighTower Advisors, LLC	UNCHANGED	16,666	16,666	0	0%	$362.0K	$336.2K	-$25.8K	2026-11-10
Deutsche Bank Ag\	NEW	12,024	—	+12,024	—	—	$242.5K	—	2026-11-06
Citigroup Inc	INCREASED	6,820	2,454	+4,366	+178%	$53.3K	$137.6K	+$84.3K	2026-11-04
Barclays PLC	INCREASED	5,600	837	+4,763	+569%	$18.2K	$113.0K	+$94.8K	2026-11-06
Strs Ohio	NEW	3,800	—	+3,800	—	—	$76.6K	—	2026-10-30
Police & Firemen's Retirement System of New Jersey	NEW	3,342	—	+3,342	—	—	$67.4K	—	2026-11-09
Assetmark, Inc	INCREASED	1,767	1,431	+336	+23%	$31.1K	$35.6K	+$4.6K	2026-10-21
Russell Investments Group, Ltd.	NEW	1,093	—	+1,093	—	—	$22.0K	—	2026-11-06
Sterling Capital Management LLC	NEW	391	—	+391	—	—	$7.9K	—	2026-10-22
Farther Finance Advisors, LLC	NEW	334	—	+334	—	—	$6.7K	—	2026-10-08
Squarepoint Ops LLC	CLOSED	0	24,753	-24,753	-100%	$537.6K	$0	-$537.6K	2026-11-09
Arch Venture Management, LLC	N/A	—	6,294,951	-6,294,951	-100%	$136.6M	—	—	—
General Atlantic, L.P.	N/A	—	6,101,582	-6,101,582	-100%	$132.5M	—	—	—
Sofinnova Investments, Inc.	N/A	—	3,564,871	-3,564,871	-100%	$77.4M	—	—	—
Goldman Sachs Group Inc	N/A	—	2,178,642	-2,178,642	-100%	$47.3M	—	—	—
TRV GP VI, LLC	N/A	—	2,061,222	-2,061,222	-100%	$44.8M	—	—	—
Canada Pension Plan Investment Board	N/A	—	1,975,791	-1,975,791	-100%	$42.9M	—	—	—
JPMorgan Chase & Co	N/A	—	1,815,845	-1,815,845	-100%	$40.9M	—	—	—
Foresite Capital Management VI LLC	N/A	—	1,779,521	-1,779,521	-100%	$38.7M	—	—	—
Price T Rowe Associates Inc	N/A	—	1,308,604	-1,308,604	-100%	$28.4K	—	—	—
Bellevue Group AG	N/A	—	1,100,000	-1,100,000	-100%	$23.9M	—	—	—
Siren, L.L.C.	N/A	—	1,095,316	-1,095,316	-100%	$23.8M	—	—	—
Jennison Associates LLC	N/A	—	1,079,669	-1,079,669	-100%	$23.5M	—	—	—
RA Capital Management, L.P.	N/A	—	700,000	-700,000	-100%	$15.2M	—	—	—
Vanguard Capital Management LLC	N/A	—	599,217	-599,217	-100%	$13.0M	—	—	—
Woodline Partners LP	N/A	—	586,345	-586,345	-100%	$12.7M	—	—	—
Perceptive Advisors LLC	N/A	—	500,000	-500,000	-100%	$10.9M	—	—	—
Braidwell LP	N/A	—	500,000	-500,000	-100%	$10.9M	—	—	—
UBS Group AG	N/A	—	279,184	-279,184	-100%	$6.1M	—	—	—
BlackRock, Inc.	N/A	—	229,863	-229,863	-100%	$5.0M	—	—	—
Seven Grand Managers, LLC	N/A	—	225,000	-225,000	-100%	$4.9M	—	—	—
Citadel Advisors LLC	N/A	—	191,144	-191,144	-100%	$4.2M	—	—	—
Pier Capital, LLC	N/A	—	169,985	-169,985	-100%	$3.7M	—	—	—
Ameriprise Financial Inc	N/A	—	131,788	-131,788	-100%	$2.9M	—	—	—
Charles Schwab Investment Management Inc	N/A	—	97,693	-97,693	-100%	$2.1M	—	—	—
Vanguard Fiduciary Trust Co	N/A	—	87,772	-87,772	-100%	$1.9M	—	—	—
Pentwater Capital Management LP	N/A	—	83,000	-83,000	-100%	$1.8M	—	—	—
Manufacturers Life Insurance Company, the	N/A	—	82,565	-82,565	-100%	$1.8M	—	—	—
Alyeska Investment Group, L.P.	N/A	—	75,000	-75,000	-100%	$1.6M	—	—	—
State Street Corp	N/A	—	66,650	-66,650	-100%	$1.4M	—	—	—
TD Asset Management Inc	N/A	—	47,944	-47,944	-100%	$1.0M	—	—	—
Millennium Management LLC	N/A	—	45,337	-45,337	-100%	$984.7K	—	—	—
GSA Capital Partners LLP	N/A	—	33,178	-33,178	-100%	$721	—	—	—
Dafna Capital Management LLC	N/A	—	32,400	-32,400	-100%	$703.7K	—	—	—
Northern Trust Corp	N/A	—	31,802	-31,802	-100%	$690.7K	—	—	—
Adar1 Capital Management, LLC	N/A	—	26,000	-26,000	-100%	$564.7K	—	—	—
Burkehill Global Management, LP	N/A	—	25,000	-25,000	-100%	$543.0K	—	—	—
Ghisallo Capital Management LLC	N/A	—	25,000	-25,000	-100%	$543.0K	—	—	—
Morgan Stanley	N/A	—	11,692	-11,692	-100%	$254.0K	—	—	—
XTX Topco Ltd	N/A	—	10,983	-10,983	-100%	$238.6K	—	—	—
Weiss Asset Management LP	N/A	—	10,000	-10,000	-100%	$217.2K	—	—	—
Zimmer Partners, LP	N/A	—	10,000	-10,000	-100%	$217.2K	—	—	—
Vanguard Portfolio Management LLC	N/A	—	9,081	-9,081	-100%	$197.2K	—	—	—
Vanguard Global Advisers, LLC	N/A	—	7,159	-7,159	-100%	$155.5K	—	—	—
Jones Financial Companies Lllp	N/A	—	2,256	-2,256	-100%	$48.3K	—	—	—

Showing 63 of 63 institutions