Spruce Biosciences Inc (SPRB)

Q2 2026 vs Q3 2026

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options 13D/13G Peers Targeting Trading Summary Profile

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Aigh Capital Management LLC

UNCHANGED

Shares250,000 from 250,000

Change0 (0%)

Value$12.1M (-$1.4M)

Filed 2026-11-02

Geode Capital Management, LLC

DECREASED

Shares66,757 from 70,548

Change-3,791 (-5%)

Value$3.2M (-$565.9K)

Filed 2026-11-06

Carlyle Group Inc.

UNCHANGED

Shares38,620 from 38,620

Change0 (0%)

Value$1.9M (-$209.3K)

Filed 2026-11-06

Dimensional Fund Advisors LP

DECREASED

Shares8,788 from 8,813

Change-25 (0%)

Value$426.4K (-$50.3K)

Filed 2026-11-04

Bank of New York Mellon Corp

INCREASED

Shares6,819 from 6,779

Change+40 (+1%)

Value$331.3K (-$34.8K)

Filed 2026-11-05

Deutsche Bank Ag\

DECREASED

Shares2,323 from 2,652

Change-329 (-12%)

Value$112.9K (-$30.4K)

Filed 2026-11-06

Barclays PLC

INCREASED

Shares1,150 from 674

Change+476 (+71%)

Value$55.9K (+$19.5K)

Filed 2026-11-06

PNC Financial Services Group, Inc.

NEW

Shares355

Change+355

Value$17.2K

Filed 2026-11-06

Russell Investments Group, Ltd.

INCREASED

Shares275 from 217

Change+58 (+27%)

Value$13.4K (+$1.6K)

Filed 2026-11-06

SBI Securities Co., Ltd.

UNCHANGED

Shares201 from 201

Change0 (0%)

Value$9.8K (-$1.1K)

Filed 2026-10-22

Pinnacle Wealth Planning Services, Inc.

NEW

Shares167

Change+167

Value$8.1K

Filed 2026-10-27

Citigroup Inc

DECREASED

Shares122 from 1,265

Change-1,143 (-90%)

Value$5.9K (-$62.4K)

Filed 2026-11-04

Parkside Financial Bank & Trust

NEW

Shares97

Change+97

Value$4.7K

Filed 2026-10-27

Gamma Investing LLC

NEW

Shares85

Change+85

Value$4.1K

Filed 2026-10-08

Sterling Capital Management LLC

INCREASED

Shares59 from 43

Change+16 (+37%)

Value$2.9K (+$544)

Filed 2026-10-22

SJS Investment Consulting Inc.

NEW

Shares17

Change+17

Value$826

Filed 2026-10-26

Root Financial Partners, LLC

NEW

Shares8

Change+8

Value$389

Filed 2026-10-21

Cassaday & Co Wealth Management LLC

UNCHANGED

Shares2 from 2

Change0 (0%)

Value$98 (-$10)

Filed 2026-10-27

Farther Finance Advisors, LLC

NEW

Shares1

Change+1

Value$49

Filed 2026-10-08

Friedenthal Financial

CLOSED

Shares0 from 7

Change-7 (-100%)

Value$0 (-$378)

Filed 2026-10-27

Orbimed Advisors LLC

N/A

Shares— from 200,000

Change-200,000 (-100%)

Value—

BlackRock, Inc.

N/A

Shares— from 187,836

Change-187,836 (-100%)

Value—

Millennium Management LLC

N/A

Shares— from 160,981

Change-160,981 (-100%)

Value—

Ikarian Capital, LLC

N/A

Shares— from 121,356

Change-121,356 (-100%)

Value—

Vanguard Capital Management LLC

N/A

Shares— from 119,331

Change-119,331 (-100%)

Value—

Alyeska Investment Group, L.P.

N/A

Shares— from 81,671

Change-81,671 (-100%)

Value—

Adar1 Capital Management, LLC

N/A

Shares— from 67,717

Change-67,717 (-100%)

Value—

Cable Car Capital, LPA

N/A

Shares— from 60,000

Change-60,000 (-100%)

Value—

Citadel Advisors LLC

N/A

Shares— from 51,905

Change-51,905 (-100%)

Value—

State Street Corp

N/A

Shares— from 50,450

Change-50,450 (-100%)

Value—

Boothbay Fund Management, LLC

N/A

Shares— from 42,080

Change-42,080 (-100%)

Value—

Stempoint Capital LP

N/A

Shares— from 41,388

Change-41,388 (-100%)

Value—

Eversept Partners, LP

N/A

Shares— from 40,000

Change-40,000 (-100%)

Value—

Goldman Sachs Group Inc

N/A

Shares— from 32,348

Change-32,348 (-100%)

Value—

Affinity Asset Advisors, LLC

N/A

Shares— from 30,000

Change-30,000 (-100%)

Value—

Diadema Partners LP

N/A

Shares— from 30,000

Change-30,000 (-100%)

Value—

Stonepine Capital Management, LLC

N/A

Shares— from 28,795

Change-28,795 (-100%)

Value—

Point72 Asset Management, L.P.

N/A

Shares— from 28,278

Change-28,278 (-100%)

Value—

Quinn Opportunity Partners LLC

N/A

Shares— from 26,810

Change-26,810 (-100%)

Value—

UBS Group AG

N/A

Shares— from 23,381

Change-23,381 (-100%)

Value—

ExodusPoint Capital Management, LP

N/A

Shares— from 22,000

Change-22,000 (-100%)

Value—

Northern Trust Corp

N/A

Shares— from 21,083

Change-21,083 (-100%)

Value—

Rosalind Advisors, Inc.

N/A

Shares— from 20,000

Change-20,000 (-100%)

Value—

Knott David M Jr

N/A

Shares— from 20,000

Change-20,000 (-100%)

Value—

Ameriprise Financial Inc

N/A

Shares— from 18,834

Change-18,834 (-100%)

Value—

Vanguard Portfolio Management LLC

N/A

Shares— from 18,496

Change-18,496 (-100%)

Value—

Vanguard Fiduciary Trust Co

N/A

Shares— from 18,361

Change-18,361 (-100%)

Value—

Balyasny Asset Management L.P.

N/A

Shares— from 12,138

Change-12,138 (-100%)

Value—

Persistent Asset Partners Ltd

N/A

Shares— from 7,677

Change-7,677 (-100%)

Value—

State Board of Administration of Florida Retirement System

N/A

Shares— from 7,182

Change-7,182 (-100%)

Value—

Charles Schwab Investment Management Inc

N/A

Shares— from 5,896

Change-5,896 (-100%)

Value—

Renaissance Technologies LLC

N/A

Shares— from 4,700

Change-4,700 (-100%)

Value—

Morgan Stanley

N/A

Shares— from 4,411

Change-4,411 (-100%)

Value—

Pale Fire Capital SE

N/A

Shares— from 3,818

Change-3,818 (-100%)

Value—

Rhumbline Advisers

N/A

Shares— from 3,519

Change-3,519 (-100%)

Value—

SkyView Investment Advisors, LLC

N/A

Shares— from 3,000

Change-3,000 (-100%)

Value—

Wells Fargo & Company

N/A

Shares— from 2,329

Change-2,329 (-100%)

Value—

New York State Common Retirement Fund

N/A

Shares— from 1,900

Change-1,900 (-100%)

Value—

Mirae Asset Global Etfs Holdings Ltd.

N/A

Shares— from 1,252

Change-1,252 (-100%)

Value—

JPMorgan Chase & Co

N/A

Shares— from 1,127

Change-1,127 (-100%)

Value—

Lion Point Capital, LP

N/A

Shares— from 1,000

Change-1,000 (-100%)

Value—

Police & Firemen's Retirement System of New Jersey

N/A

Shares— from 864

Change-864 (-100%)

Value—

BNP Paribas Financial Markets

N/A

Shares— from 453

Change-453 (-100%)

Value—

Vanguard Global Advisers, LLC

N/A

Shares— from 452

Change-452 (-100%)

Value—

FMR LLC

N/A

Shares— from 343

Change-343 (-100%)

Value—

Legal & General Group Plc

N/A

Shares— from 264

Change-264 (-100%)

Value—

Ameritas Investment Partners, Inc.

N/A

Shares— from 247

Change-247 (-100%)

Value—

Tower Research Capital LLC (TRC)

N/A

Shares— from 246

Change-246 (-100%)

Value—

Royal Bank of Canada

N/A

Shares— from 166

Change-166 (-100%)

Value—

Jones Financial Companies Lllp

N/A

Shares— from 30

Change-30 (-100%)

Value—

Caldwell Sutter Capital, Inc.

N/A

Shares— from 13

Change-13 (-100%)

Value—

	Status
Aigh Capital Management LLC	UNCHANGED	250,000	250,000	0	0%	$13.5M	$12.1M	-$1.4M	2026-11-02
Geode Capital Management, LLC	DECREASED	66,757	70,548	-3,791	-5%	$3.8M	$3.2M	-$565.9K	2026-11-06
Carlyle Group Inc.	UNCHANGED	38,620	38,620	0	0%	$2.1M	$1.9M	-$209.3K	2026-11-06
Dimensional Fund Advisors LP	DECREASED	8,788	8,813	-25	0%	$476.7K	$426.4K	-$50.3K	2026-11-04
Bank of New York Mellon Corp	INCREASED	6,819	6,779	+40	+1%	$366.1K	$331.3K	-$34.8K	2026-11-05
Deutsche Bank Ag\	DECREASED	2,323	2,652	-329	-12%	$143.2K	$112.9K	-$30.4K	2026-11-06
Barclays PLC	INCREASED	1,150	674	+476	+71%	$36.4K	$55.9K	+$19.5K	2026-11-06
PNC Financial Services Group, Inc.	NEW	355	—	+355	—	—	$17.2K	—	2026-11-06
Russell Investments Group, Ltd.	INCREASED	275	217	+58	+27%	$11.7K	$13.4K	+$1.6K	2026-11-06
SBI Securities Co., Ltd.	UNCHANGED	201	201	0	0%	$10.9K	$9.8K	-$1.1K	2026-10-22
Pinnacle Wealth Planning Services, Inc.	NEW	167	—	+167	—	—	$8.1K	—	2026-10-27
Citigroup Inc	DECREASED	122	1,265	-1,143	-90%	$68.3K	$5.9K	-$62.4K	2026-11-04
Parkside Financial Bank & Trust	NEW	97	—	+97	—	—	$4.7K	—	2026-10-27
Gamma Investing LLC	NEW	85	—	+85	—	—	$4.1K	—	2026-10-08
Sterling Capital Management LLC	INCREASED	59	43	+16	+37%	$2.3K	$2.9K	+$544	2026-10-22
SJS Investment Consulting Inc.	NEW	17	—	+17	—	—	$826	—	2026-10-26
Root Financial Partners, LLC	NEW	8	—	+8	—	—	$389	—	2026-10-21
Cassaday & Co Wealth Management LLC	UNCHANGED	2	2	0	0%	$108	$98	-$10	2026-10-27
Farther Finance Advisors, LLC	NEW	1	—	+1	—	—	$49	—	2026-10-08
Friedenthal Financial	CLOSED	0	7	-7	-100%	$378	$0	-$378	2026-10-27
Orbimed Advisors LLC	N/A	—	200,000	-200,000	-100%	$10.8M	—	—	—
BlackRock, Inc.	N/A	—	187,836	-187,836	-100%	$10.1M	—	—	—
Millennium Management LLC	N/A	—	160,981	-160,981	-100%	$8.7M	—	—	—
Ikarian Capital, LLC	N/A	—	121,356	-121,356	-100%	$6.6M	—	—	—
Vanguard Capital Management LLC	N/A	—	119,331	-119,331	-100%	$6.4M	—	—	—
Alyeska Investment Group, L.P.	N/A	—	81,671	-81,671	-100%	$4.4M	—	—	—
Adar1 Capital Management, LLC	N/A	—	67,717	-67,717	-100%	$3.7M	—	—	—
Cable Car Capital, LPA	N/A	—	60,000	-60,000	-100%	$3.2M	—	—	—
Citadel Advisors LLC	N/A	—	51,905	-51,905	-100%	$2.8M	—	—	—
State Street Corp	N/A	—	50,450	-50,450	-100%	$2.7M	—	—	—
Boothbay Fund Management, LLC	N/A	—	42,080	-42,080	-100%	$2.3M	—	—	—
Stempoint Capital LP	N/A	—	41,388	-41,388	-100%	$2.2M	—	—	—
Eversept Partners, LP	N/A	—	40,000	-40,000	-100%	$2.2M	—	—	—
Goldman Sachs Group Inc	N/A	—	32,348	-32,348	-100%	$1.7M	—	—	—
Affinity Asset Advisors, LLC	N/A	—	30,000	-30,000	-100%	$1.6M	—	—	—
Diadema Partners LP	N/A	—	30,000	-30,000	-100%	$1.6M	—	—	—
Stonepine Capital Management, LLC	N/A	—	28,795	-28,795	-100%	$1.6M	—	—	—
Point72 Asset Management, L.P.	N/A	—	28,278	-28,278	-100%	$1.5M	—	—	—
Quinn Opportunity Partners LLC	N/A	—	26,810	-26,810	-100%	$1.4M	—	—	—
UBS Group AG	N/A	—	23,381	-23,381	-100%	$1.3M	—	—	—
ExodusPoint Capital Management, LP	N/A	—	22,000	-22,000	-100%	$1.2M	—	—	—
Northern Trust Corp	N/A	—	21,083	-21,083	-100%	$1.1M	—	—	—
Rosalind Advisors, Inc.	N/A	—	20,000	-20,000	-100%	$1.1M	—	—	—
Knott David M Jr	N/A	—	20,000	-20,000	-100%	$1.1M	—	—	—
Ameriprise Financial Inc	N/A	—	18,834	-18,834	-100%	$1.0M	—	—	—
Vanguard Portfolio Management LLC	N/A	—	18,496	-18,496	-100%	$998.8K	—	—	—
Vanguard Fiduciary Trust Co	N/A	—	18,361	-18,361	-100%	$991.5K	—	—	—
Balyasny Asset Management L.P.	N/A	—	12,138	-12,138	-100%	$655.5K	—	—	—
Persistent Asset Partners Ltd	N/A	—	7,677	-7,677	-100%	$414.6K	—	—	—
State Board of Administration of Florida Retirement System	N/A	—	7,182	-7,182	-100%	$387.8K	—	—	—
Charles Schwab Investment Management Inc	N/A	—	5,896	-5,896	-100%	$318.4K	—	—	—
Renaissance Technologies LLC	N/A	—	4,700	-4,700	-100%	$253.8K	—	—	—
Morgan Stanley	N/A	—	4,411	-4,411	-100%	$238.2K	—	—	—
Pale Fire Capital SE	N/A	—	3,818	-3,818	-100%	$206.2K	—	—	—
Rhumbline Advisers	N/A	—	3,519	-3,519	-100%	$190.0K	—	—	—
SkyView Investment Advisors, LLC	N/A	—	3,000	-3,000	-100%	$162.0K	—	—	—
Wells Fargo & Company	N/A	—	2,329	-2,329	-100%	$125.8K	—	—	—
New York State Common Retirement Fund	N/A	—	1,900	-1,900	-100%	$102.6K	—	—	—
Mirae Asset Global Etfs Holdings Ltd.	N/A	—	1,252	-1,252	-100%	$67.6K	—	—	—
JPMorgan Chase & Co	N/A	—	1,127	-1,127	-100%	$63.0K	—	—	—
Lion Point Capital, LP	N/A	—	1,000	-1,000	-100%	$54.0K	—	—	—
Police & Firemen's Retirement System of New Jersey	N/A	—	864	-864	-100%	$46.7K	—	—	—
BNP Paribas Financial Markets	N/A	—	453	-453	-100%	$24.5K	—	—	—
Vanguard Global Advisers, LLC	N/A	—	452	-452	-100%	$24.4K	—	—	—
FMR LLC	N/A	—	343	-343	-100%	$18.5K	—	—	—
Legal & General Group Plc	N/A	—	264	-264	-100%	$14.2K	—	—	—
Ameritas Investment Partners, Inc.	N/A	—	247	-247	-100%	$13.3K	—	—	—
Tower Research Capital LLC (TRC)	N/A	—	246	-246	-100%	$13.3K	—	—	—
Royal Bank of Canada	N/A	—	166	-166	-100%	$8.0K	—	—	—
Jones Financial Companies Lllp	N/A	—	30	-30	-100%	$1.7K	—	—	—
Caldwell Sutter Capital, Inc.	N/A	—	13	-13	-100%	$702	—	—	—

Showing 71 of 71 institutions