Vigil Neuroscience Inc (VIGL)

Q2 2025 vs Q3 2025

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options Short Interest 13D/13G Peers Targeting Trading Summary Profile

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XTX Topco Ltd

INCREASED

Shares26,298 from 11,527

Change+14,771 (+128%)

Value$0 (-$91.6K)

Filed 2025-11-14

Osaic Holdings, Inc.

UNCHANGED

Shares565 from 565

Change0 (0%)

Value$4.5K (+$57)

Filed 2025-11-14

Atlas Venture Life Science Advisors, LLC

CLOSED

Shares0 from 5,836,874

Change-5,836,874 (-100%)

Value$0 (-$46.4M)

Filed 2025-11-13

Beryl Capital Management LLC

CLOSED

Shares0 from 4,606,267

Change-4,606,267 (-100%)

Value$0 (-$36.6M)

Filed 2025-11-14

Glazer Capital, LLC

CLOSED

Shares0 from 3,012,068

Change-3,012,068 (-100%)

Value$0 (-$23.9K)

Filed 2025-11-13

Oddo BHF Asset Management SAS

CLOSED

Shares0 from 2,300,000

Change-2,300,000 (-100%)

Value$0 (-$18.3M)

Filed 2026-11-09

683 Capital Management, LLC

CLOSED

Shares0 from 1,261,772

Change-1,261,772 (-100%)

Value$0 (-$10.0M)

Filed 2025-11-14

Vanguard Group Inc

CLOSED

Shares0 from 1,260,942

Change-1,260,942 (-100%)

Value$0 (-$10.0M)

Filed 2025-11-07

Gabelli Funds LLC

CLOSED

Shares0 from 1,189,528

Change-1,189,528 (-100%)

Value$0 (-$9.5M)

Filed 2025-11-12

Alpine Associates Management Inc.

CLOSED

Shares0 from 1,094,900

Change-1,094,900 (-100%)

Value$0 (-$8.7M)

Filed 2025-11-06

Opaleye Management Inc.

CLOSED

Shares0 from 1,000,000

Change-1,000,000 (-100%)

Value$0 (-$8.0M)

Filed 2025-11-14

Highbridge Capital Management LLC

CLOSED

Shares0 from 865,036

Change-865,036 (-100%)

Value$0 (-$6.9M)

Filed 2025-11-10

Gabelli & Co Investment Advisers, Inc.

CLOSED

Shares0 from 864,950

Change-864,950 (-100%)

Value$0 (-$6.9M)

Filed 2025-11-12

Woodline Partners LP

CLOSED

Shares0 from 653,619

Change-653,619 (-100%)

Value$0 (-$5.2M)

Filed 2025-11-14

Pivotal bioVenture Partners Investment Advisor LLC

CLOSED

Shares0 from 560,595

Change-560,595 (-100%)

Value$0 (-$4.5M)

Filed 2025-11-13

FIL Ltd

CLOSED

Shares0 from 558,762

Change-558,762 (-100%)

Value$0 (-$4.4M)

Filed 2025-11-13

Qube Research & Technologies Ltd

CLOSED

Shares0 from 536,256

Change-536,256 (-100%)

Value$0 (-$4.3M)

Filed 2025-11-14

Renaissance Technologies LLC

CLOSED

Shares0 from 535,800

Change-535,800 (-100%)

Value$0 (-$4.3M)

Filed 2025-11-13

Chicago Capital Management, LLC

CLOSED

Shares0 from 482,769

Change-482,769 (-100%)

Value$0 (-$3.8M)

Filed 2025-11-07

Quinn Opportunity Partners LLC

CLOSED

Shares0 from 450,000

Change-450,000 (-100%)

Value$0 (-$3.6M)

Filed 2025-11-13

BlackRock, Inc.

CLOSED

Shares0 from 415,316

Change-415,316 (-100%)

Value$0 (-$3.3M)

Filed 2025-11-12

Siren, L.L.C.

CLOSED

Shares0 from 411,191

Change-411,191 (-100%)

Value$0 (-$3.3M)

Filed 2025-11-13

JPMorgan Chase & Co

CLOSED

Shares0 from 396,926

Change-396,926 (-100%)

Value$0 (-$3.2M)

Filed 2025-11-26

Irenic Capital Management LPA

CLOSED

Shares0 from 371,321

Change-371,321 (-100%)

Value$0 (-$3.0M)

Filed 2025-11-14

Geode Capital Management, LLC

CLOSED

Shares0 from 304,071

Change-304,071 (-100%)

Value$0 (-$2.4M)

Filed 2025-11-12

UBS Group AG

CLOSED

Shares0 from 302,468

Change-302,468 (-100%)

Value$0 (-$2.4M)

Filed 2025-11-13

ArrowMark Colorado Holdings LLC

CLOSED

Shares0 from 289,460

Change-289,460 (-100%)

Value$0 (-$2.3M)

Filed 2025-11-14

Squarepoint Ops LLC

CLOSED

Shares0 from 286,980

Change-286,980 (-100%)

Value$0 (-$2.3M)

Filed 2025-11-14

Millennium Management LLC

CLOSED

Shares0 from 279,253

Change-279,253 (-100%)

Value$0 (-$2.2M)

Filed 2025-11-14

Skandinaviska Enskilda Banken AB (publ)

CLOSED

Shares0 from 275,998

Change-275,998 (-100%)

Value$0 (-$2.2M)

Filed 2025-11-07

Carmignac Gestion

CLOSED

Shares0 from 241,755

Change-241,755 (-100%)

Value$0 (-$1.9M)

Filed 2025-11-13

Black Maple Capital Management LP

CLOSED

Shares0 from 215,992

Change-215,992 (-100%)

Value$0 (-$1.7M)

Filed 2025-11-14

Water Island Capital LLC

CLOSED

Shares0 from 207,667

Change-207,667 (-100%)

Value$0 (-$1.7M)

Filed 2025-11-14

Shay Capital LLC

CLOSED

Shares0 from 203,887

Change-203,887 (-100%)

Value$0 (-$1.6M)

Filed 2025-11-14

Trustees of Columbia University in the City of New York

CLOSED

Shares0 from 192,973

Change-192,973 (-100%)

Value$0 (-$1.5M)

Filed 2025-11-14

ABC Arbitrage SA

CLOSED

Shares0 from 183,179

Change-183,179 (-100%)

Value$0 (-$1.5M)

Filed 2025-11-06

ExodusPoint Capital Management, LP

CLOSED

Shares0 from 137,830

Change-137,830 (-100%)

Value$0 (-$1.1K)

Filed 2025-11-14

Omers Administration Corp

CLOSED

Shares0 from 128,500

Change-128,500 (-100%)

Value$0 (-$1.0M)

Filed 2025-11-14

Groupe la Francaise

CLOSED

Shares0 from 120,000

Change-120,000 (-100%)

Value$0 (-$954.0K)

Filed 2025-11-13

Prelude Capital Management, LLC

CLOSED

Shares0 from 118,568

Change-118,568 (-100%)

Value$0 (-$942.6K)

Filed 2025-11-14

State Street Corp

CLOSED

Shares0 from 109,399

Change-109,399 (-100%)

Value$0 (-$869.7K)

Filed 2025-11-14

Credit Industriel ET Commercial

CLOSED

Shares0 from 80,000

Change-80,000 (-100%)

Value$0 (-$636.0K)

Filed 2025-11-07

Gamco Investors, Inc. ET AL

CLOSED

Shares0 from 75,000

Change-75,000 (-100%)

Value$0 (-$596.3K)

Filed 2025-11-12

Northern Trust Corp

CLOSED

Shares0 from 71,588

Change-71,588 (-100%)

Value$0 (-$569.1K)

Filed 2025-11-14

JBF Capital, Inc.

CLOSED

Shares0 from 70,000

Change-70,000 (-100%)

Value$0 (-$556.5K)

Filed 2025-11-14

Rangeley Capital, LLC

CLOSED

Shares0 from 67,800

Change-67,800 (-100%)

Value$0 (-$539.0K)

Filed 2025-11-14

Quadrature Capital Ltd

CLOSED

Shares0 from 62,271

Change-62,271 (-100%)

Value$0 (-$495.4K)

Filed 2025-11-13

Mint Tower Capital Management B.V.

CLOSED

Shares0 from 60,381

Change-60,381 (-100%)

Value$0 (-$480)

Filed 2025-11-12

Virtu Financial LLC

CLOSED

Shares0 from 58,331

Change-58,331 (-100%)

Value$0 (-$464)

Filed 2025-11-14

CSS LLC

CLOSED

Shares0 from 56,200

Change-56,200 (-100%)

Value$0 (-$446.8K)

Filed 2025-11-13

PenderFund Capital Management Ltd.

CLOSED

Shares0 from 55,000

Change-55,000 (-100%)

Value$0 (-$437.3K)

Filed 2025-11-14

New York Life Investment Management LLC

CLOSED

Shares0 from 53,069

Change-53,069 (-100%)

Value$0 (-$421.9K)

Filed 2025-11-06

GSA Capital Partners LLP

CLOSED

Shares0 from 44,179

Change-44,179 (-100%)

Value$0 (-$351)

Filed 2025-11-07

SG Americas Securities, LLC

CLOSED

Shares0 from 43,508

Change-43,508 (-100%)

Value$0 (-$346)

Filed 2025-10-23

Goldman Sachs Group Inc

CLOSED

Shares0 from 42,562

Change-42,562 (-100%)

Value$0 (-$338.4K)

Filed 2025-11-14

Citadel Advisors LLC

CLOSED

Shares0 from 33,766

Change-33,766 (-100%)

Value$0 (-$268.4K)

Filed 2025-11-14

Ikarian Capital, LLC

CLOSED

Shares0 from 31,360

Change-31,360 (-100%)

Value$0 (-$249.3K)

Filed 2025-11-14

FNY Investment Advisers, LLC

CLOSED

Shares0 from 30,235

Change-30,235 (-100%)

Value$0 (-$240)

Filed 2025-12-15

Deltec Asset Management LLC

CLOSED

Shares0 from 30,000

Change-30,000 (-100%)

Value$0 (-$238.5K)

Filed 2025-10-24

Marshall Wace, LLP

CLOSED

Shares0 from 25,900

Change-25,900 (-100%)

Value$0 (-$205.9K)

Filed 2025-11-13

GTS Securities LLC

CLOSED

Shares0 from 25,000

Change-25,000 (-100%)

Value$0 (-$198.8K)

Filed 2025-11-14

Point72 Asia (Singapore) Pte. Ltd.

CLOSED

Shares0 from 24,132

Change-24,132 (-100%)

Value$0 (-$191.9K)

Filed 2025-11-14

American Century Companies Inc

CLOSED

Shares0 from 22,879

Change-22,879 (-100%)

Value$0 (-$181.9K)

Filed 2025-11-12

Charles Schwab Investment Management Inc

CLOSED

Shares0 from 20,643

Change-20,643 (-100%)

Value$0 (-$164.1K)

Filed 2025-11-10

Private Advisor Group, LLC

CLOSED

Shares0 from 16,000

Change-16,000 (-100%)

Value$0 (-$127.2K)

Filed 2025-11-13

CreativeOne Wealth, LLC

CLOSED

Shares0 from 13,500

Change-13,500 (-100%)

Value$0 (-$107.3K)

Filed 2025-11-13

Morgan Stanley

CLOSED

Shares0 from 13,091

Change-13,091 (-100%)

Value$0 (-$104.1K)

Filed 2026-05-27

Vanguard Personalized Indexing Management, LLC

CLOSED

Shares0 from 11,198

Change-11,198 (-100%)

Value$0 (-$89.0K)

Filed 2025-10-31

Longfellow Investment Management Co LLC

CLOSED

Shares0 from 9,243

Change-9,243 (-100%)

Value$0 (-$73.5K)

Filed 2025-11-12

Citigroup Inc

CLOSED

Shares0 from 3,500

Change-3,500 (-100%)

Value$0 (-$27.8K)

Filed 2025-11-10

Royal Bank of Canada

CLOSED

Shares0 from 1,290

Change-1,290 (-100%)

Value$0 (-$10.0K)

Filed 2025-11-14

Bank of America Corp

CLOSED

Shares0 from 1,186

Change-1,186 (-100%)

Value$0 (-$9.4K)

Filed 2026-02-03

Wells Fargo & Company

CLOSED

Shares0 from 615

Change-615 (-100%)

Value$0 (-$4.9K)

Filed 2025-11-13

Raymond James Financial Inc

CLOSED

Shares0 from 501

Change-501 (-100%)

Value$0 (-$4.0K)

Filed 2025-11-14

Atlantic Union Bankshares Corp

CLOSED

Shares0 from 225

Change-225 (-100%)

Value$0 (-$1.8K)

Filed 2025-11-04

BNP Paribas Financial Markets

CLOSED

Shares0 from 150

Change-150 (-100%)

Value$0 (-$1.2K)

Filed 2025-11-13

Point72 (Difc) Ltd

CLOSED

Shares0 from 6

Change-6 (-100%)

Value$0 (-$47)

Filed 2025-11-14

SBI Securities Co., Ltd.

CLOSED

Shares0 from 1

Change-1 (-100%)

Value$0 (-$8)

Filed 2025-11-05

Proequities, Inc.

N/A

Shares— from 0

Change0

Value—

	Status
XTX Topco Ltd	INCREASED	26,298	11,527	+14,771	+128%	$91.6K	$0	-$91.6K	2025-11-14
Osaic Holdings, Inc.	UNCHANGED	565	565	0	0%	$4.5K	$4.5K	+$57	2025-11-14
Atlas Venture Life Science Advisors, LLC	CLOSED	0	5,836,874	-5,836,874	-100%	$46.4M	$0	-$46.4M	2025-11-13
Beryl Capital Management LLC	CLOSED	0	4,606,267	-4,606,267	-100%	$36.6M	$0	-$36.6M	2025-11-14
Glazer Capital, LLC	CLOSED	0	3,012,068	-3,012,068	-100%	$23.9K	$0	-$23.9K	2025-11-13
Oddo BHF Asset Management SAS	CLOSED	0	2,300,000	-2,300,000	-100%	$18.3M	$0	-$18.3M	2026-11-09
683 Capital Management, LLC	CLOSED	0	1,261,772	-1,261,772	-100%	$10.0M	$0	-$10.0M	2025-11-14
Vanguard Group Inc	CLOSED	0	1,260,942	-1,260,942	-100%	$10.0M	$0	-$10.0M	2025-11-07
Gabelli Funds LLC	CLOSED	0	1,189,528	-1,189,528	-100%	$9.5M	$0	-$9.5M	2025-11-12
Alpine Associates Management Inc.	CLOSED	0	1,094,900	-1,094,900	-100%	$8.7M	$0	-$8.7M	2025-11-06
Opaleye Management Inc.	CLOSED	0	1,000,000	-1,000,000	-100%	$8.0M	$0	-$8.0M	2025-11-14
Highbridge Capital Management LLC	CLOSED	0	865,036	-865,036	-100%	$6.9M	$0	-$6.9M	2025-11-10
Gabelli & Co Investment Advisers, Inc.	CLOSED	0	864,950	-864,950	-100%	$6.9M	$0	-$6.9M	2025-11-12
Woodline Partners LP	CLOSED	0	653,619	-653,619	-100%	$5.2M	$0	-$5.2M	2025-11-14
Pivotal bioVenture Partners Investment Advisor LLC	CLOSED	0	560,595	-560,595	-100%	$4.5M	$0	-$4.5M	2025-11-13
FIL Ltd	CLOSED	0	558,762	-558,762	-100%	$4.4M	$0	-$4.4M	2025-11-13
Qube Research & Technologies Ltd	CLOSED	0	536,256	-536,256	-100%	$4.3M	$0	-$4.3M	2025-11-14
Renaissance Technologies LLC	CLOSED	0	535,800	-535,800	-100%	$4.3M	$0	-$4.3M	2025-11-13
Chicago Capital Management, LLC	CLOSED	0	482,769	-482,769	-100%	$3.8M	$0	-$3.8M	2025-11-07
Quinn Opportunity Partners LLC	CLOSED	0	450,000	-450,000	-100%	$3.6M	$0	-$3.6M	2025-11-13
BlackRock, Inc.	CLOSED	0	415,316	-415,316	-100%	$3.3M	$0	-$3.3M	2025-11-12
Siren, L.L.C.	CLOSED	0	411,191	-411,191	-100%	$3.3M	$0	-$3.3M	2025-11-13
JPMorgan Chase & Co	CLOSED	0	396,926	-396,926	-100%	$3.2M	$0	-$3.2M	2025-11-26
Irenic Capital Management LPA	CLOSED	0	371,321	-371,321	-100%	$3.0M	$0	-$3.0M	2025-11-14
Geode Capital Management, LLC	CLOSED	0	304,071	-304,071	-100%	$2.4M	$0	-$2.4M	2025-11-12
UBS Group AG	CLOSED	0	302,468	-302,468	-100%	$2.4M	$0	-$2.4M	2025-11-13
ArrowMark Colorado Holdings LLC	CLOSED	0	289,460	-289,460	-100%	$2.3M	$0	-$2.3M	2025-11-14
Squarepoint Ops LLC	CLOSED	0	286,980	-286,980	-100%	$2.3M	$0	-$2.3M	2025-11-14
Millennium Management LLC	CLOSED	0	279,253	-279,253	-100%	$2.2M	$0	-$2.2M	2025-11-14
Skandinaviska Enskilda Banken AB (publ)	CLOSED	0	275,998	-275,998	-100%	$2.2M	$0	-$2.2M	2025-11-07
Carmignac Gestion	CLOSED	0	241,755	-241,755	-100%	$1.9M	$0	-$1.9M	2025-11-13
Black Maple Capital Management LP	CLOSED	0	215,992	-215,992	-100%	$1.7M	$0	-$1.7M	2025-11-14
Water Island Capital LLC	CLOSED	0	207,667	-207,667	-100%	$1.7M	$0	-$1.7M	2025-11-14
Shay Capital LLC	CLOSED	0	203,887	-203,887	-100%	$1.6M	$0	-$1.6M	2025-11-14
Trustees of Columbia University in the City of New York	CLOSED	0	192,973	-192,973	-100%	$1.5M	$0	-$1.5M	2025-11-14
ABC Arbitrage SA	CLOSED	0	183,179	-183,179	-100%	$1.5M	$0	-$1.5M	2025-11-06
ExodusPoint Capital Management, LP	CLOSED	0	137,830	-137,830	-100%	$1.1K	$0	-$1.1K	2025-11-14
Omers Administration Corp	CLOSED	0	128,500	-128,500	-100%	$1.0M	$0	-$1.0M	2025-11-14
Groupe la Francaise	CLOSED	0	120,000	-120,000	-100%	$954.0K	$0	-$954.0K	2025-11-13
Prelude Capital Management, LLC	CLOSED	0	118,568	-118,568	-100%	$942.6K	$0	-$942.6K	2025-11-14
State Street Corp	CLOSED	0	109,399	-109,399	-100%	$869.7K	$0	-$869.7K	2025-11-14
Credit Industriel ET Commercial	CLOSED	0	80,000	-80,000	-100%	$636.0K	$0	-$636.0K	2025-11-07
Gamco Investors, Inc. ET AL	CLOSED	0	75,000	-75,000	-100%	$596.3K	$0	-$596.3K	2025-11-12
Northern Trust Corp	CLOSED	0	71,588	-71,588	-100%	$569.1K	$0	-$569.1K	2025-11-14
JBF Capital, Inc.	CLOSED	0	70,000	-70,000	-100%	$556.5K	$0	-$556.5K	2025-11-14
Rangeley Capital, LLC	CLOSED	0	67,800	-67,800	-100%	$539.0K	$0	-$539.0K	2025-11-14
Quadrature Capital Ltd	CLOSED	0	62,271	-62,271	-100%	$495.4K	$0	-$495.4K	2025-11-13
Mint Tower Capital Management B.V.	CLOSED	0	60,381	-60,381	-100%	$480	$0	-$480	2025-11-12
Virtu Financial LLC	CLOSED	0	58,331	-58,331	-100%	$464	$0	-$464	2025-11-14
CSS LLC	CLOSED	0	56,200	-56,200	-100%	$446.8K	$0	-$446.8K	2025-11-13
PenderFund Capital Management Ltd.	CLOSED	0	55,000	-55,000	-100%	$437.3K	$0	-$437.3K	2025-11-14
New York Life Investment Management LLC	CLOSED	0	53,069	-53,069	-100%	$421.9K	$0	-$421.9K	2025-11-06
GSA Capital Partners LLP	CLOSED	0	44,179	-44,179	-100%	$351	$0	-$351	2025-11-07
SG Americas Securities, LLC	CLOSED	0	43,508	-43,508	-100%	$346	$0	-$346	2025-10-23
Goldman Sachs Group Inc	CLOSED	0	42,562	-42,562	-100%	$338.4K	$0	-$338.4K	2025-11-14
Citadel Advisors LLC	CLOSED	0	33,766	-33,766	-100%	$268.4K	$0	-$268.4K	2025-11-14
Ikarian Capital, LLC	CLOSED	0	31,360	-31,360	-100%	$249.3K	$0	-$249.3K	2025-11-14
FNY Investment Advisers, LLC	CLOSED	0	30,235	-30,235	-100%	$240	$0	-$240	2025-12-15
Deltec Asset Management LLC	CLOSED	0	30,000	-30,000	-100%	$238.5K	$0	-$238.5K	2025-10-24
Marshall Wace, LLP	CLOSED	0	25,900	-25,900	-100%	$205.9K	$0	-$205.9K	2025-11-13
GTS Securities LLC	CLOSED	0	25,000	-25,000	-100%	$198.8K	$0	-$198.8K	2025-11-14
Point72 Asia (Singapore) Pte. Ltd.	CLOSED	0	24,132	-24,132	-100%	$191.9K	$0	-$191.9K	2025-11-14
American Century Companies Inc	CLOSED	0	22,879	-22,879	-100%	$181.9K	$0	-$181.9K	2025-11-12
Charles Schwab Investment Management Inc	CLOSED	0	20,643	-20,643	-100%	$164.1K	$0	-$164.1K	2025-11-10
Private Advisor Group, LLC	CLOSED	0	16,000	-16,000	-100%	$127.2K	$0	-$127.2K	2025-11-13
CreativeOne Wealth, LLC	CLOSED	0	13,500	-13,500	-100%	$107.3K	$0	-$107.3K	2025-11-13
Morgan Stanley	CLOSED	0	13,091	-13,091	-100%	$104.1K	$0	-$104.1K	2026-05-27
Vanguard Personalized Indexing Management, LLC	CLOSED	0	11,198	-11,198	-100%	$89.0K	$0	-$89.0K	2025-10-31
Longfellow Investment Management Co LLC	CLOSED	0	9,243	-9,243	-100%	$73.5K	$0	-$73.5K	2025-11-12
Citigroup Inc	CLOSED	0	3,500	-3,500	-100%	$27.8K	$0	-$27.8K	2025-11-10
Royal Bank of Canada	CLOSED	0	1,290	-1,290	-100%	$10.0K	$0	-$10.0K	2025-11-14
Bank of America Corp	CLOSED	0	1,186	-1,186	-100%	$9.4K	$0	-$9.4K	2026-02-03
Wells Fargo & Company	CLOSED	0	615	-615	-100%	$4.9K	$0	-$4.9K	2025-11-13
Raymond James Financial Inc	CLOSED	0	501	-501	-100%	$4.0K	$0	-$4.0K	2025-11-14
Atlantic Union Bankshares Corp	CLOSED	0	225	-225	-100%	$1.8K	$0	-$1.8K	2025-11-04
BNP Paribas Financial Markets	CLOSED	0	150	-150	-100%	$1.2K	$0	-$1.2K	2025-11-13
Point72 (Difc) Ltd	CLOSED	0	6	-6	-100%	$47	$0	-$47	2025-11-14
SBI Securities Co., Ltd.	CLOSED	0	1	-1	-100%	$8	$0	-$8	2025-11-05
Proequities, Inc.	N/A	—	0	0	—	$0	—	—	—

Showing 79 of 79 institutions