Vyne Therapeutics Inc (VYNE)

Q1 2026 vs Q2 2026

Comparing institutional holders between quarters

Compare Detailed Historical Funds Options 13D/13G Peers Targeting Trading Summary Profile

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Adar1 Capital Management, LLC

INCREASED

Shares2,950,000 from 1,063,899

Change+1,886,101 (+177%)

Value$1.9M (+$1.3M)

Filed 2026-08-14

Nantahala Capital Management, LLC

UNCHANGED

Shares2,000,000 from 2,000,000

Change0 (0%)

Value$1.3M (+$106.4K)

Filed 2026-08-19

Lynx1 Capital Management LP

UNCHANGED

Shares1,628,700 from 1,628,700

Change0 (0%)

Value$1.1M (+$86.6K)

Filed 2026-08-13

Shay Capital LLC

DECREASED

Shares1,456,651 from 1,610,242

Change-153,591 (-10%)

Value$947.8K (-$14.3K)

Filed 2026-08-14

Deeter Investments LLP

UNCHANGED

Shares1,000,000 from 1,000,000

Change0 (0%)

Value$650.7K (+$53.2K)

Filed 2026-10-08

T3 Companies, LLC

UNCHANGED

Shares945,000 from 945,000

Change0 (0%)

Value$614.9K (+$50.3K)

Filed 2026-07-27

Braidwell LP

UNCHANGED

Shares916,077 from 916,077

Change0 (0%)

Value$596.1K (+$48.7K)

Filed 2026-08-14

KVP Capital Advisors, LP

UNCHANGED

Shares500,551 from 500,551

Change0 (0%)

Value$325.7K (+$26.6K)

Filed 2026-08-13

Citadel Advisors LLC

DECREASED

Shares468,457 from 514,443

Change-45,986 (-9%)

Value$304.8K (-$2.6K)

Filed 2026-09-02

Two Sigma Investments, LP

INCREASED

Shares438,818 from 426,412

Change+12,406 (+3%)

Value$285.5K (+$30.8K)

Filed 2026-08-14

Acadian Asset Management LLC

UNCHANGED

Shares381,797 from 381,797

Change0 (0%)

Value$248.0K (+$247.8K)

Filed 2026-08-13

Ikarian Capital, LLC

UNCHANGED

Shares264,912 from 264,912

Change0 (0%)

Value$172.4K (+$14.1K)

Filed 2026-08-14

Vanguard Capital Management LLC

UNCHANGED

Shares264,557 from 264,557

Change0 (0%)

Value$172.2K (+$14.0K)

Filed 2026-08-13

Geode Capital Management, LLC

DECREASED

Shares258,203 from 322,711

Change-64,508 (-20%)

Value$168.0K (-$24.8K)

Filed 2026-08-12

Vanguard Fiduciary Trust Co

NEW

Shares183,443

Change+183,443

Value$119.4K

Filed 2026-08-13

Susquehanna International Group, LLP

INCREASED

Shares118,957 from 57,784

Change+61,173 (+106%)

Value$77.4K (+$42.9K)

Filed 2026-08-14

Rangeley Capital, LLC

DECREASED

Shares113,064 from 118,064

Change-5,000 (-4%)

Value$73.6K (+$3.0K)

Filed 2026-08-14

XTX Topco Ltd

DECREASED

Shares78,721 from 158,396

Change-79,675 (-50%)

Value$51.2K (-$43.4K)

Filed 2026-08-14

GSA Capital Partners LLP

NEW

Shares71,533

Change+71,533

Value$47.0K

Filed 2026-08-06

Superstring Capital Management LP

NEW

Shares61,269

Change+61,269

Value$39.9K

Filed 2026-08-14

UBS Group AG

DECREASED

Shares58,597 from 179,784

Change-121,187 (-67%)

Value$38.1K (-$69.4K)

Filed 2026-08-13

BlackRock, Inc.

UNCHANGED

Shares44,405 from 44,405

Change0 (0%)

Value$28.9K (+$2.4K)

Filed 2026-08-07

Northern Trust Corp

INCREASED

Shares43,677 from 23,110

Change+20,567 (+89%)

Value$28.4K (+$14.6K)

Filed 2026-08-13

Jane Street Group, LLC

DECREASED

Shares40,974 from 95,645

Change-54,671 (-57%)

Value$26.7K (-$30.5K)

Filed 2026-08-14

Two Sigma Securities, LLC

NEW

Shares40,697

Change+40,697

Value$26.5K

Filed 2026-08-14

FNY Investment Advisers, LLC

UNCHANGED

Shares35,000 from 35,000

Change0 (0%)

Value$22 (+$2)

Filed 2026-07-08

Renaissance Technologies LLC

INCREASED

Shares23,300 from 17,300

Change+6,000 (+35%)

Value$15.2K (+$4.8K)

Filed 2026-08-13

Commonwealth Equity Services, LLC

UNCHANGED

Shares18,298 from 18,298

Change0 (0%)

Value$11.9K (+$980)

Filed 2026-07-29

State Street Corp

UNCHANGED

Shares15,765 from 15,765

Change0 (0%)

Value$10.3K (+$838)

Filed 2026-09-22

Anson Funds Management LPA

DECREASED

Shares14,455 from 1,243,106

Change-1,228,651 (-99%)

Value$9.4K (-$733.4K)

Filed 2026-08-13

Tower Research Capital LLC (TRC)

INCREASED

Shares12,994 from 3,527

Change+9,467 (+268%)

Value$8.5K (+$6.3K)

Filed 2026-08-11

Harvest Investment Services, LLC

UNCHANGED

Shares11,059 from 11,059

Change0 (0%)

Value$7.2K (+$588)

Filed 2026-08-14

Acorn Capital Advisors, LLC

UNCHANGED

Shares1,425 from 1,425

Change0 (0%)

Value$926 (+$71)

Filed 2026-08-14

MB, Levis & Associates, LLC

UNCHANGED

Shares1,041 from 1,041

Change0 (0%)

Value$677 (+$55)

Filed 2026-07-22

Hurley Capital, LLC

UNCHANGED

Shares561 from 561

Change0 (0%)

Value$365 (+$30)

Filed 2026-08-10

Centerpoint Advisors, LLC

UNCHANGED

Shares350 from 350

Change0 (0%)

Value$0 ($0)

Filed 2026-08-05

Barclays PLC

NEW

Shares141

Change+141

Value$92

Filed 2026-08-14

Wells Fargo & Company

UNCHANGED

Shares65 from 65

Change0 (0%)

Value$42 (+$3)

Filed 2026-08-14

Morgan Stanley

UNCHANGED

Shares43 from 43

Change0 (0%)

Value$28 (+$2)

Filed 2026-08-13

Truvestments Capital LLC

UNCHANGED

Shares25 from 25

Change0 (0%)

Value$16 (+$1)

Filed 2026-08-12

Royal Bank of Canada

UNCHANGED

Shares15 from 15

Change0 (0%)

Value$0 ($0)

Filed 2026-08-14

Nfsg Corp

UNCHANGED

Shares10 from 10

Change0 (0%)

Value$7 (+$1)

Filed 2026-08-14

JPMorgan Chase & Co

DECREASED

Shares8 from 146

Change-138 (-95%)

Value$5 (-$81)

Filed 2026-08-12

Larson Financial Group LLC

UNCHANGED

Shares2 from 2

Change0 (0%)

Value$1 ($0)

Filed 2026-08-14

Flagship Wealth Advisors, LLC

NEW

Shares1

Change+1

Value$1

Filed 2026-07-27

Steward Partners Investment Advisory, LLC

NEW

Shares1

Change+1

Value$1

Filed 2026-08-13

Boothbay Fund Management, LLC

CLOSED

Shares0 from 81,371

Change-81,371 (-100%)

Value$0 (-$48.6K)

Filed 2026-08-14

HRT Financial LP

CLOSED

Shares0 from 27,569

Change-27,569 (-100%)

Value$0 (-$16)

Filed 2026-08-14

Northwestern Mutual Wealth Management Co

CLOSED

Shares0 from 800

Change-800 (-100%)

Value$0 (-$478)

Filed 2026-08-12

CWM, LLC

N/A

Shares— from 500

Change-500 (-100%)

Value—

Vanguard Group Inc

N/A

Shares— from 0

Change0

Value—

	Status
Adar1 Capital Management, LLC	INCREASED	2,950,000	1,063,899	+1,886,101	+177%	$635.7K	$1.9M	+$1.3M	2026-08-14
Nantahala Capital Management, LLC	UNCHANGED	2,000,000	2,000,000	0	0%	$1.2M	$1.3M	+$106.4K	2026-08-19
Lynx1 Capital Management LP	UNCHANGED	1,628,700	1,628,700	0	0%	$973.1K	$1.1M	+$86.6K	2026-08-13
Shay Capital LLC	DECREASED	1,456,651	1,610,242	-153,591	-10%	$962.1K	$947.8K	-$14.3K	2026-08-14
Deeter Investments LLP	UNCHANGED	1,000,000	1,000,000	0	0%	$597.5K	$650.7K	+$53.2K	2026-10-08
T3 Companies, LLC	UNCHANGED	945,000	945,000	0	0%	$564.6K	$614.9K	+$50.3K	2026-07-27
Braidwell LP	UNCHANGED	916,077	916,077	0	0%	$547.4K	$596.1K	+$48.7K	2026-08-14
KVP Capital Advisors, LP	UNCHANGED	500,551	500,551	0	0%	$299.1K	$325.7K	+$26.6K	2026-08-13
Citadel Advisors LLC	DECREASED	468,457	514,443	-45,986	-9%	$307.4K	$304.8K	-$2.6K	2026-09-02
Two Sigma Investments, LP	INCREASED	438,818	426,412	+12,406	+3%	$254.8K	$285.5K	+$30.8K	2026-08-14
Acadian Asset Management LLC	UNCHANGED	381,797	381,797	0	0%	$228	$248.0K	+$247.8K	2026-08-13
Ikarian Capital, LLC	UNCHANGED	264,912	264,912	0	0%	$158.3K	$172.4K	+$14.1K	2026-08-14
Vanguard Capital Management LLC	UNCHANGED	264,557	264,557	0	0%	$158.2K	$172.2K	+$14.0K	2026-08-13
Geode Capital Management, LLC	DECREASED	258,203	322,711	-64,508	-20%	$192.8K	$168.0K	-$24.8K	2026-08-12
Vanguard Fiduciary Trust Co	NEW	183,443	—	+183,443	—	—	$119.4K	—	2026-08-13
Susquehanna International Group, LLP	INCREASED	118,957	57,784	+61,173	+106%	$34.5K	$77.4K	+$42.9K	2026-08-14
Rangeley Capital, LLC	DECREASED	113,064	118,064	-5,000	-4%	$70.5K	$73.6K	+$3.0K	2026-08-14
XTX Topco Ltd	DECREASED	78,721	158,396	-79,675	-50%	$94.6K	$51.2K	-$43.4K	2026-08-14
GSA Capital Partners LLP	NEW	71,533	—	+71,533	—	—	$47.0K	—	2026-08-06
Superstring Capital Management LP	NEW	61,269	—	+61,269	—	—	$39.9K	—	2026-08-14
UBS Group AG	DECREASED	58,597	179,784	-121,187	-67%	$107.5K	$38.1K	-$69.4K	2026-08-13
BlackRock, Inc.	UNCHANGED	44,405	44,405	0	0%	$26.5K	$28.9K	+$2.4K	2026-08-07
Northern Trust Corp	INCREASED	43,677	23,110	+20,567	+89%	$13.8K	$28.4K	+$14.6K	2026-08-13
Jane Street Group, LLC	DECREASED	40,974	95,645	-54,671	-57%	$57.1K	$26.7K	-$30.5K	2026-08-14
Two Sigma Securities, LLC	NEW	40,697	—	+40,697	—	—	$26.5K	—	2026-08-14
FNY Investment Advisers, LLC	UNCHANGED	35,000	35,000	0	0%	$20	$22	+$2	2026-07-08
Renaissance Technologies LLC	INCREASED	23,300	17,300	+6,000	+35%	$10.3K	$15.2K	+$4.8K	2026-08-13
Commonwealth Equity Services, LLC	UNCHANGED	18,298	18,298	0	0%	$10.9K	$11.9K	+$980	2026-07-29
State Street Corp	UNCHANGED	15,765	15,765	0	0%	$9.4K	$10.3K	+$838	2026-09-22
Anson Funds Management LPA	DECREASED	14,455	1,243,106	-1,228,651	-99%	$742.8K	$9.4K	-$733.4K	2026-08-13
Tower Research Capital LLC (TRC)	INCREASED	12,994	3,527	+9,467	+268%	$2.1K	$8.5K	+$6.3K	2026-08-11
Harvest Investment Services, LLC	UNCHANGED	11,059	11,059	0	0%	$6.6K	$7.2K	+$588	2026-08-14
Acorn Capital Advisors, LLC	UNCHANGED	1,425	1,425	0	0%	$855	$926	+$71	2026-08-14
MB, Levis & Associates, LLC	UNCHANGED	1,041	1,041	0	0%	$622	$677	+$55	2026-07-22
Hurley Capital, LLC	UNCHANGED	561	561	0	0%	$335	$365	+$30	2026-08-10
Centerpoint Advisors, LLC	UNCHANGED	350	350	0	0%	$0	$0	$0	2026-08-05
Barclays PLC	NEW	141	—	+141	—	—	$92	—	2026-08-14
Wells Fargo & Company	UNCHANGED	65	65	0	0%	$39	$42	+$3	2026-08-14
Morgan Stanley	UNCHANGED	43	43	0	0%	$26	$28	+$2	2026-08-13
Truvestments Capital LLC	UNCHANGED	25	25	0	0%	$15	$16	+$1	2026-08-12
Royal Bank of Canada	UNCHANGED	15	15	0	0%	$0	$0	$0	2026-08-14
Nfsg Corp	UNCHANGED	10	10	0	0%	$6	$7	+$1	2026-08-14
JPMorgan Chase & Co	DECREASED	8	146	-138	-95%	$86	$5	-$81	2026-08-12
Larson Financial Group LLC	UNCHANGED	2	2	0	0%	$1	$1	$0	2026-08-14
Flagship Wealth Advisors, LLC	NEW	1	—	+1	—	—	$1	—	2026-07-27
Steward Partners Investment Advisory, LLC	NEW	1	—	+1	—	—	$1	—	2026-08-13
Boothbay Fund Management, LLC	CLOSED	0	81,371	-81,371	-100%	$48.6K	$0	-$48.6K	2026-08-14
HRT Financial LP	CLOSED	0	27,569	-27,569	-100%	$16	$0	-$16	2026-08-14
Northwestern Mutual Wealth Management Co	CLOSED	0	800	-800	-100%	$478	$0	-$478	2026-08-12
CWM, LLC	N/A	—	500	-500	-100%	$299	—	—	—
Vanguard Group Inc	N/A	—	0	0	—	$0	—	—	—

Showing 51 of 51 institutions