Q4 2024 Holdings
Filed 2025-02-14 | 59 holdings | $2.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
Sign in to see sub-manager breakdown
| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $379.4M | 11,890,843 | 14.3% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $220.0M | 15,028,079 | 8.3% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $219.3M | 4,288,120 | 8.3% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $210.2M | 1,706,469 | 7.9% |
| Prothena Corp PLC(PRTA) | SHS | G72800108 | $160.4M | 11,584,280 | 6.1% |
| Xencor Inc(XNCR) | COM | 98401F105 | $141.2M | 6,144,767 | 5.3% |
| Pfizer Inc(PFE)Call | COM | 717081103 | $132.7M | 5,000,000 | 5.0% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $128.9M | 6,726,491 | 4.9% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $104.2M | 7,873,448 | 3.9% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $93.6M | 770,000 | 3.5% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $78.7M | 1,469,818 | 3.0% |
| Uniqure NV(QURE) | SHS | N90064101 | $60.0M | 3,400,000 | 2.3% |
| Springworks Therapeutics Inc | COM | 85205L107 | $56.4M | 1,560,000 | 2.1% |
| Crispr Therapeutics AG(CRSP) | NAMEN AKT | H17182108 | $54.7M | 1,389,276 | 2.1% |
| Immunome Inc(IMNM) | COM | 45257U108 | $41.2M | 3,879,415 | 1.6% |
| Tectonic Therapeutic Inc(TECX) | COM | 878972108 | $39.2M | 849,143 | 1.5% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $32.8M | 10,630,736 | 1.2% |
| Third Harmonic BIO Inc(THRD) | COM | 88427A107 | $32.7M | 3,182,444 | 1.2% |
| Kura Oncology Inc(KURA) | COM | 50127T109 | $31.0M | 3,557,269 | 1.2% |
| Neurogene Inc(NGNE) | COM | 64135M105 | $29.1M | 1,271,342 | 1.1% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $27.6M | 3,418,068 | 1.0% |
| Eton Pharmaceuticals Inc(ETON) | COM | 29772L108 | $24.4M | 1,829,603 | 0.9% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $23.2M | 1,259,273 | 0.9% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $23.1M | 75,000 | 0.9% |
| Voyager Therapeutics Inc(VYGR) | COM | 92915B106 | $22.2M | 3,917,546 | 0.8% |
| Neumora Therapeutics Inc.(NMRA) | COM | 640979100 | $22.0M | 2,071,450 | 0.8% |
| Cargo Therapeutics Inc(CRGX) | COM | 14179K101 | $21.2M | 1,470,000 | 0.8% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $18.0M | 332,522 | 0.7% |
| Ginkgo Bioworks Holdings Inc(DNA) | CL A NEW | 37611X209 | $17.1M | 1,743,344 | 0.6% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $16.2M | 557,576 | 0.6% |
| Mersana Therapeutics Inc | COM | 59045L106 | $16.2M | 11,328,000 | 0.6% |
| Tscan Therapeutics Inc(TCRX) | COM | 89854M101 | $15.2M | 5,000,000 | 0.6% |
| Adaptimmune Therapeutics PLC(ADAPY) | SPONDS ADR | 00653A107 | $14.8M | 27,404,070 | 0.6% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $14.1M | 350,000 | 0.5% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $13.1M | 555,644 | 0.5% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $12.7M | 910,000 | 0.5% |
| Atea Pharmaceuticals Inc(AVIR) | COM | 04683R106 | $11.2M | 3,341,653 | 0.4% |
| DAY One Biopharmaceuticals I(DAWN) | COM | 23954D109 | $10.9M | 862,068 | 0.4% |
| Replimune Group Inc(REPL) | COM | 76029N106 | $10.3M | 850,341 | 0.4% |
| Aligos Therapeutics Inc(ALGS) | COM NEW | 01626L204 | $10.2M | 255,573 | 0.4% |
| Atara Biotherapeutics Inc(ATRA) | COM NEW | 046513206 | $7.1M | 532,134 | 0.3% |
| Verve Therapeutics Inc | COM | 92539P101 | $7.1M | 1,250,000 | 0.3% |
| Uniqure NV(QURE)Call | SHS | N90064101 | $6.8M | 385,000 | 0.3% |
| Fate Therapeutics Inc(FATE) | COM | 31189P102 | $5.0M | 3,049,405 | 0.2% |
| Galapagos NV(GLPG) | SPON ADR | 36315X101 | $4.3M | 155,006 | 0.2% |
| Allovir Inc | COM | 019818103 | $3.9M | 408,688 | 0.1% |
| Keros Therapeutics Inc(KROS) | COM | 492327101 | $3.0M | 187,500 | 0.1% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $2.6M | 641,426 | 0.1% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $2.6M | 426,683 | 0.1% |
| Nuvation BIO Inc(NUVB/WS) | *W EXP 02/10/202 | 67080N119 | $2.6M | 963,333 | 0.1% |