Q4 2021 Holdings
Filed 2022-02-10 | 235 holdings | $1.7B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $349.2M | 997,038 | 20.2% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $226.4M | 1,335,140 | 13.1% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $183.5M | 2,233,403 | 10.6% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $143.0M | 4,349,292 | 8.3% |
| Biogen Inc(BIIB) | COM | 09062X103 | $126.0M | 525,000 | 7.3% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $125.9M | 2,964,031 | 7.3% |
| Align Technology Inc(ALGN) | COM | 016255101 | $96.3M | 146,564 | 5.6% |
| Caredx Inc(CDNA) | COM | 14167L103 | $66.7M | 1,466,552 | 3.9% |
| Adaptive Biotechnologies COR(ADPT) | COM | 00650F109 | $55.2M | 1,968,431 | 3.2% |
| Centene Corp del(CNC) | COM | 15135B101 | $54.4M | 660,010 | 3.1% |
| Beam Therapeutics Inc(BEAM) | COM | 07373V105 | $48.8M | 612,821 | 2.8% |
| Abbvie Inc(ABBV) | COM | 00287Y109 | $41.6M | 306,900 | 2.4% |
| Atricure Inc(ATRC) | COM | 04963C209 | $34.7M | 498,556 | 2.0% |
| BIO RAD Labs Inc(BIO) | CL A | 090572207 | $30.0M | 39,683 | 1.7% |
| Biontech SE(BNTX) | SPONSORED ADS | 09075V102 | $29.3M | 113,466 | 1.7% |
| Charles RIV Labs Intl Inc(CRL) | COM | 159864107 | $24.8M | 65,911 | 1.4% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $24.6M | 651,937 | 1.4% |
| Avantor Inc(AVTR) | COM | 05352A100 | $21.6M | 512,216 | 1.2% |
| Black Diamond Therapeutics I(BDTX) | COM | 09203E105 | $18.5M | 3,463,000 | 1.1% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $6.3M | 71,400 | 0.4% |
| Beigene LTD(ONC) | SPONSORED ADR | 07725L102 | $6.2M | 23,000 | 0.4% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $3.5M | 87,500 | 0.2% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $3.3M | 53,700 | 0.2% |
| Arcturus Therapeutics Hldgs(ARCT) | COM | 03969T109 | $1.5M | 41,600 | 0.1% |
| C4 Therapeutics Inc(CCCC) | COM STK | 12529R107 | $1.5M | 47,200 | 0.1% |
| Cellectis S A(CLLS) | SPON ADS | 15117K103 | $670.0K | 82,500 | 0.0% |
| Moderna Inc(MRNA) | COM | 60770K107 | $434.1K | 1,709,249 | 0.0% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $393.5K | 1,791,761 | 0.0% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $315.1K | 10,355,123 | 0.0% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $270.9K | 3,180,551 | 0.0% |
| Abbott Labs(ABT) | COM | 002824100 | $245.7K | 1,745,801 | 0.0% |
| Fate Therapeutics Inc(FATE) | COM | 31189P102 | $220.9K | 3,775,736 | 0.0% |
| Incyte Corp(INCY) | COM | 45337C102 | $217.0K | 2,957,000 | 0.0% |
| Anthem Inc(ELV) | COM | 036752103 | $211.0K | 455,294 | 0.0% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $210.0K | 584,463 | 0.0% |
| Danaher Corporation(DHR) | COM | 235851102 | $194.7K | 591,800 | 0.0% |
| Intra-Cellular Therapies Inc(ITCIEUR) | COM | 46116X101 | $189.9K | 3,628,919 | 0.0% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $156.8K | 312,281 | 0.0% |
| Tandem Diabetes Care Inc(TNDM) | COM NEW | 875372203 | $142.9K | 949,257 | 0.0% |
| Humana Inc(HUM) | COM | 444859102 | $140.9K | 303,697 | 0.0% |
| Macrogenics Inc(MGNX) | COM | 556099109 | $137.4K | 8,560,462 | 0.0% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $137.3K | 3,228,004 | 0.0% |
| Dexcom Inc(DXCM) | COM | 252131107 | $126.3K | 235,153 | 0.0% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $126.1K | 4,105,962 | 0.0% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $119.3K | 921,185 | 0.0% |
| Becton Dickinson & Co(BDX) | COM | 075887109 | $114.5K | 455,412 | 0.0% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $113.0K | 886,854 | 0.0% |
| Stryker Corporation(SYK) | COM | 863667101 | $112.8K | 421,884 | 0.0% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $104.8K | 1,872,014 | 0.0% |
| Insulet Corp(PODD) | COM | 45784P101 | $101.8K | 382,723 | 0.0% |