Q1 2023 Holdings
Filed 2023-05-15 | 202 holdings | $6.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $361.0M | 1,145,695 | 5.2% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $340.0M | 9,511,900 | 4.9% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $330.5M | 886,928 | 4.8% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $264.5M | 2,613,300 | 3.8% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $247.5M | 968,786 | 3.6% |
| Moderna Inc(MRNA) | COM | 60770K107 | $238.3M | 1,551,706 | 3.5% |
| Incyte Corp(INCY) | COM | 45337C102 | $205.3M | 2,840,500 | 3.0% |
| Intra-Cellular Therapies Inc(ITCIEUR) | COM | 46116X101 | $177.0M | 3,268,000 | 2.6% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $176.9M | 883,250 | 2.6% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $172.1M | 3,439,579 | 2.5% |
| Abbott Labs(ABT) | COM | 002824100 | $166.8M | 1,646,916 | 2.4% |
| Stryker Corporation(SYK) | COM | 863667101 | $138.4M | 484,774 | 2.0% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $129.7M | 3,090,000 | 1.9% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $104.3M | 1,911,861 | 1.5% |
| Insulet Corp(PODD) | COM | 45784P101 | $103.2M | 323,594 | 1.5% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $102.8M | 4,747,900 | 1.5% |
| Medtronic PLC(MDT) | SHS | G5960L103 | $99.1M | 1,229,235 | 1.4% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $92.2M | 4,013,500 | 1.3% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $92.1M | 194,811 | 1.3% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $89.1M | 646,614 | 1.3% |
| Inspire MED SYS Inc(INSP) | COM | 457730109 | $88.3M | 377,068 | 1.3% |
| Dexcom Inc(DXCM) | COM | 252131107 | $87.7M | 755,079 | 1.3% |
| Becton Dickinson & Co(BDX) | COM | 075887109 | $86.2M | 348,043 | 1.3% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $86.1M | 1,040,669 | 1.2% |
| Danaher Corporation(DHR) | COM | 235851102 | $85.0M | 337,391 | 1.2% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $83.4M | 569,857 | 1.2% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $83.1M | 1,225,042 | 1.2% |
| Pacific Biosciences Calif in(PACB) | COM | 69404D108 | $81.4M | 7,026,106 | 1.2% |
| HCA Healthcare Inc(HCA) | COM | 40412C101 | $80.1M | 303,786 | 1.2% |
| Option Care Health Inc(OPCH) | COM NEW | 68404L201 | $77.6M | 2,442,185 | 1.1% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $73.2M | 1,109,382 | 1.1% |
| Tandem Diabetes Care Inc(TNDM) | COM NEW | 875372203 | $72.8M | 1,793,763 | 1.1% |
| Evolent Health Inc(EVH) | CL A | 30050B101 | $71.1M | 2,191,147 | 1.0% |
| Macrogenics Inc(MGNX) | COM | 556099109 | $68.9M | 9,609,913 | 1.0% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $68.7M | 4,172,600 | 1.0% |
| Penumbra Inc(PEN) | COM | 70975L107 | $66.4M | 238,172 | 1.0% |
| Celldex Therapeutics Inc(CLDX) | COM NEW | 15117B202 | $64.8M | 1,800,000 | 0.9% |
| Charles RIV Labs Intl Inc(CRL) | COM | 159864107 | $61.0M | 302,446 | 0.9% |
| Shockwave MED Inc(SWAVUSD) | COM | 82489T104 | $61.0M | 281,376 | 0.9% |
| Accolade Inc(ACCDEUR) | COM | 00437E102 | $58.1M | 4,041,801 | 0.8% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $58.1M | 2,127,000 | 0.8% |
| Align Technology Inc(ALGN) | COM | 016255101 | $57.2M | 171,140 | 0.8% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $56.1M | 3,293,102 | 0.8% |
| Idexx Labs Inc(IDXX) | COM | 45168D104 | $55.5M | 110,928 | 0.8% |
| BIO RAD Labs Inc(BIO) | CL A | 090572207 | $54.5M | 113,739 | 0.8% |
| Outset MED Inc(OMGBP) | COM | 690145107 | $53.5M | 2,906,759 | 0.8% |
| Exelixis Inc(EXEL) | COM | 30161Q104 | $50.6M | 2,609,000 | 0.7% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $49.8M | 86,333 | 0.7% |
| Veeva SYS Inc(VEEV) | CL A COM | 922475108 | $48.3M | 262,985 | 0.7% |
| Transmedics Group Inc(TMDX) | COM | 89377M109 | $47.7M | 629,484 | 0.7% |