Q4 2023 Holdings
Filed 2024-02-14 | 202 holdings | $6.5B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $440.8M | 8,713,987 | 6.7% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $330.7M | 869,208 | 5.1% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $320.2M | 2,430,500 | 4.9% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $299.6M | 736,390 | 4.6% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $280.7M | 832,041 | 4.3% |
| Intra-Cellular Therapies Inc(ITCIEUR) | COM | 46116X101 | $219.6M | 3,066,400 | 3.4% |
| Moderna Inc(MRNA) | COM | 60770K107 | $189.8M | 1,908,420 | 2.9% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $183.3M | 3,170,603 | 2.8% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $169.5M | 885,318 | 2.6% |
| Abbott Labs(ABT) | COM | 002824100 | $169.0M | 1,535,656 | 2.6% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $146.0M | 5,091,000 | 2.2% |
| Stryker Corporation(SYK) | COM | 863667101 | $139.5M | 465,724 | 2.1% |
| Incyte Corp(INCY) | COM | 45337C102 | $135.4M | 2,156,719 | 2.1% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $114.1M | 1,833,165 | 1.7% |
| Dexcom Inc(DXCM) | COM | 252131107 | $113.5M | 914,593 | 1.7% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $103.2M | 2,507,731 | 1.6% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $95.8M | 2,416,296 | 1.5% |
| Macrogenics Inc(MGNX) | COM | 556099109 | $95.8M | 9,953,313 | 1.5% |
| Becton Dickinson & Co(BDX) | COM | 075887109 | $94.6M | 388,068 | 1.4% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $89.3M | 4,011,000 | 1.4% |
| Medtronic PLC(MDT) | SHS | G5960L103 | $80.0M | 970,772 | 1.2% |
| Evolent Health Inc(EVH) | CL A | 30050B101 | $78.5M | 2,376,992 | 1.2% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $77.7M | 1,018,998 | 1.2% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $77.5M | 1,047,786 | 1.2% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $76.1M | 3,513,351 | 1.2% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $72.7M | 138,152 | 1.1% |
| Pacific Biosciences Calif in(PACB) | COM | 69404D108 | $71.8M | 7,317,128 | 1.1% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $71.0M | 2,290,958 | 1.1% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $66.7M | 976,054 | 1.0% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $65.4M | 5,936,082 | 1.0% |
| Option Care Health Inc(OPCH) | COM NEW | 68404L201 | $65.3M | 1,938,807 | 1.0% |
| Insulet Corp(PODD) | COM | 45784P101 | $62.9M | 289,900 | 1.0% |
| Tandem Diabetes Care Inc(TNDM) | COM NEW | 875372203 | $58.9M | 1,992,317 | 0.9% |
| Crispr Therapeutics AG(CRSP) | NAMEN AKT | H17182108 | $56.4M | 900,400 | 0.9% |
| Accolade Inc(ACCDEUR) | COM | 00437E102 | $54.1M | 4,507,404 | 0.8% |
| Idexx Labs Inc(IDXX) | COM | 45168D104 | $52.2M | 94,110 | 0.8% |
| Essa Pharma Inc(EPIEUR) | COM NEW | 29668H708 | $52.1M | 7,898,583 | 0.8% |
| Charles RIV Labs Intl Inc(CRL) | COM | 159864107 | $51.5M | 217,756 | 0.8% |
| Penumbra Inc(PEN) | COM | 70975L107 | $51.1M | 203,046 | 0.8% |
| Elevance Health Inc(ELV) | COM | 036752103 | $50.8M | 107,788 | 0.8% |
| Exelixis Inc(EXEL) | COM | 30161Q104 | $50.6M | 2,108,100 | 0.8% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $50.6M | 635,372 | 0.8% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $49.2M | 821,800 | 0.8% |
| Caredx Inc(CDNA) | COM | 14167L103 | $47.5M | 3,954,792 | 0.7% |
| Biohaven LTD(BHVN) | COM | G1110E107 | $46.0M | 1,075,000 | 0.7% |
| Humana Inc(HUM) | COM | 444859102 | $46.0M | 100,472 | 0.7% |
| BIO RAD Labs Inc(BIO) | CL A | 090572207 | $45.6M | 141,147 | 0.7% |
| Inspire MED SYS Inc(INSP) | COM | 457730109 | $43.9M | 215,600 | 0.7% |
| Align Technology Inc(ALGN) | COM | 016255101 | $43.7M | 159,407 | 0.7% |
| GE Healthcare Technologies I(GEHC) | COMMON STOCK | 36266G107 | $41.4M | 535,184 | 0.6% |