Q1 2023 Holdings
Filed 2023-05-15 | 99 holdings | $3.4B | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2023-05-16) | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $306.8M | 27,662,917 | 9.1% |
| Reata Pharmaceuticals Inc(RETAEUR) | CL A | 75615P103 | $197.2M | 2,169,276 | 5.8% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $177.1M | 6,034,644 | 5.2% |
| Cerevel Therapeutics Hldng I(CERE1EUR) | COM | 15678U128 | $158.9M | 6,511,727 | 4.7% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $157.6M | 650,562 | 4.7% |
| Prometheus Biosciences Inc | COM | 74349U108 | $136.6M | 1,272,694 | 4.0% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $118.4M | 3,841,739 | 3.5% |
| Lianbio | SPONSORED ADS | 53000N108 | $112.8M | 57,558,451 | 3.3% |
| Aldeyra Therapeutics Inc(ALDX) | COM | 01438T106 | $112.7M | 11,350,085 | 3.3% |
| Iovance Biotherapeutics Inc(IOVA) | COM | 462260100 | $93.7M | 15,339,735 | 2.8% |
| Inhibrx Inc(INBXUSD) | COM | 45720L107 | $68.2M | 3,615,383 | 2.0% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $65.6M | 1,832,174 | 1.9% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $65.4M | 673,060 | 1.9% |
| Treace MED Concepts Inc(TMCI) | COM | 89455T109 | $61.5M | 2,442,250 | 1.8% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $60.0M | 2,300,048 | 1.8% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $58.5M | 1,574,134 | 1.7% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $57.1M | 3,554,887 | 1.7% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $54.9M | 2,733,790 | 1.6% |
| Springworks Therapeutics Inc | COM | 85205L107 | $53.5M | 2,079,352 | 1.6% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $44.6M | 2,278,226 | 1.3% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $44.2M | 1,736,386 | 1.3% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $43.9M | 1,170,000 | 1.3% |
| Rapt Therapeutics Inc(RAPTEUR) | COM | 75382E109 | $42.1M | 2,291,608 | 1.2% |
| Sanofi(SNY) | SPONSORED ADR | 80105N105 | $41.8M | 768,101 | 1.2% |
| Adma Biologics Inc(ADMA) | COM | 000899104 | $39.4M | 11,900,255 | 1.2% |
| Natera Inc(NTRA) | COM | 632307104 | $39.3M | 707,214 | 1.2% |
| Acrivon Therapeutics Inc(ACRV) | COMMON STOCK | 004890109 | $38.2M | 3,007,858 | 1.1% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $36.6M | 555,344 | 1.1% |
| Meiragtx Hldgs PLC(MGTX) | COM | G59665102 | $36.0M | 6,963,277 | 1.1% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $36.0M | 260,858 | 1.1% |
| Bellus Health Inc New(BLU) | COM NEW | 07987C204 | $35.7M | 4,952,538 | 1.1% |
| Cymabay Therapeutics Inc(CBAYUSD) | COM | 23257D103 | $34.0M | 3,903,255 | 1.0% |
| Verrica Pharmaceuticals Inc | COM | 92511W108 | $32.8M | 5,038,983 | 1.0% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $32.0M | 1,943,097 | 0.9% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $31.7M | 467,857 | 0.9% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $31.6M | 1,907,033 | 0.9% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $30.5M | 3,378,498 | 0.9% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $29.1M | 2,189,462 | 0.9% |
| Nautilus Biotechnology Inc(NAUT) | COM | 63909J108 | $25.2M | 9,111,151 | 0.7% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $24.6M | 2,282,324 | 0.7% |
| Immatics N.v(IMTX) | SHS | N44445109 | $24.1M | 3,491,500 | 0.7% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $22.2M | 965,152 | 0.7% |
| Outset MED Inc(OMGBP) | COM | 690145107 | $20.0M | 1,089,427 | 0.6% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $20.0M | 1,291,858 | 0.6% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $20.0M | 523,525 | 0.6% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $19.9M | 2,692,136 | 0.6% |
| Lyra Therapeutics Inc(LYRA) | COM | 55234L105 | $18.4M | 9,146,730 | 0.5% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $16.6M | 3,495,933 | 0.5% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $16.3M | 1,296,416 | 0.5% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $16.0M | 1,350,000 | 0.5% |