Q4 2025 Holdings
Filed 2026-02-17 | 213 holdings | $5.3B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $398.7M | 5,005,719 | 7.6% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $388.4M | 461,854 | 7.4% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $379.9M | 4,802,199 | 7.2% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $308.8M | 681,120 | 5.9% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $241.6M | 1,703,304 | 4.6% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $189.8M | 2,630,969 | 3.6% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $182.4M | 322,028 | 3.5% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $178.7M | 4,056,592 | 3.4% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $177.3M | 445,903 | 3.4% |
| Abbott Labs(ABT) | COM | 002824100 | $165.0M | 1,316,915 | 3.1% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $152.9M | 10,735,195 | 2.9% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $148.7M | 1,559,606 | 2.8% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $135.6M | 4,358,527 | 2.6% |
| Stryker Corporation(SYK) | COM | 863667101 | $126.7M | 360,577 | 2.4% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $104.4M | 1,037,468 | 2.0% |
| Krystal Biotech Inc(KRYS) | COM | 501147102 | $101.2M | 410,323 | 1.9% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $98.3M | 3,617,669 | 1.9% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $97.1M | 2,796,803 | 1.8% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $88.9M | 1,043,096 | 1.7% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $86.0M | 1,698,152 | 1.6% |
| Medtronic PLC(MDT) | SHS | G5960L103 | $73.6M | 766,592 | 1.4% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $70.6M | 8,345,364 | 1.3% |
| Idexx Labs Inc(IDXX) | COM | 45168D104 | $64.0M | 94,539 | 1.2% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $57.8M | 175,169 | 1.1% |
| Dexcom Inc(DXCM) | COM | 252131107 | $56.2M | 847,405 | 1.1% |
| Insulet Corp(PODD) | COM | 45784P101 | $53.1M | 186,699 | 1.0% |
| Becton Dickinson & Co(BDX) | COM | 075887109 | $51.6M | 265,662 | 1.0% |
| Jade Biosciences Inc(JBIO) | COM NEW | 008064206 | $51.6M | 3,341,103 | 1.0% |
| Danaher Corporation(DHR) | COM | 235851102 | $44.6M | 194,633 | 0.8% |
| Penumbra Inc(PEN) | COM | 70975L107 | $42.1M | 135,395 | 0.8% |
| Resmed Inc(RMD) | COM | 761152107 | $38.8M | 161,214 | 0.7% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $37.9M | 1,528,518 | 0.7% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $37.7M | 65,077 | 0.7% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $36.8M | 887,708 | 0.7% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $36.5M | 34,003 | 0.7% |
| GE Healthcare Technologies I(GEHC) | COMMON STOCK | 36266G107 | $34.8M | 424,514 | 0.7% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $34.8M | 3,927,670 | 0.7% |
| Abbvie Inc(ABBV) | COM | 00287Y109 | $30.8M | 134,859 | 0.6% |
| The Cigna Group(CI) | COM | 125523100 | $30.3M | 110,013 | 0.6% |
| Glaukos Corp(GKOS) | COM | 377322102 | $29.6M | 261,935 | 0.6% |
| Johnson & Johnson(JNJ) | COM | 478160104 | $26.2M | 126,800 | 0.5% |
| Annexon Inc(ANNX) | COM | 03589W102 | $25.9M | 5,157,290 | 0.5% |
| Steris PLC(STE) | SHS USD | G8473T100 | $25.8M | 101,705 | 0.5% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $25.3M | 1,490,518 | 0.5% |
| Elevance Health Inc Formerly(ELV) | COM | 036752103 | $24.4M | 69,645 | 0.5% |
| Cooper COS Inc(COO) | COM | 216648501 | $23.9M | 291,959 | 0.5% |
| Globus MED Inc(GMED) | CL A | 379577208 | $22.9M | 262,683 | 0.4% |
| Align Technology Inc(ALGN) | COM | 016255101 | $22.1M | 141,474 | 0.4% |
| Zimmer Biomet Holdings Inc(ZBH) | COM | 98956P102 | $21.5M | 238,680 | 0.4% |
| Mckesson Corp(MCK) | COM | 58155Q103 | $20.6M | 25,098 | 0.4% |