Q4 2025 Holdings
Filed 2026-02-17 | 99 holdings | $2.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| ELI Lilly & Co(LLY) | COM | 532457108 | $113.3M | 105,400 | 5.8% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $106.4M | 1,335,270 | 5.5% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $86.8M | 103,250 | 4.5% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $84.5M | 2,210,322 | 4.3% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $81.3M | 139,618 | 4.2% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $74.4M | 695,010 | 3.8% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $61.1M | 601,800 | 3.1% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $60.2M | 762,294 | 3.1% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $55.6M | 319,250 | 2.8% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $52.0M | 748,236 | 2.7% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $46.4M | 82,000 | 2.4% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $45.3M | 204,878 | 2.3% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $43.4M | 203,500 | 2.2% |
| Irhythm Technologies Inc(IRTC) | COM | 450056106 | $41.7M | 235,000 | 2.1% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $38.7M | 496,871 | 2.0% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $38.0M | 399,050 | 2.0% |
| Penumbra Inc(PEN) | COM | 70975L107 | $37.5M | 120,500 | 1.9% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $35.3M | 787,788 | 1.8% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $32.3M | 733,477 | 1.7% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $30.2M | 849,030 | 1.5% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $29.1M | 1,267,241 | 1.5% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $28.8M | 568,579 | 1.5% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $28.3M | 71,250 | 1.5% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $27.5M | 1,929,931 | 1.4% |
| Spdr Series Trust(XBI) | STATE STREET SPD | 78464A870 | $27.1M | 222,000 | 1.4% |
| Tenet Healthcare Corp(THC) | COM NEW | 88033G407 | $24.8M | 125,000 | 1.3% |
| Dexcom Inc(DXCM) | COM | 252131107 | $23.1M | 347,300 | 1.2% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $21.8M | 799,163 | 1.1% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $21.3M | 260,344 | 1.1% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $21.1M | 3,927,202 | 1.1% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $19.5M | 557,194 | 1.0% |
| Azenta Inc(AZTA) | COM | 114340102 | $18.9M | 569,100 | 1.0% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $18.8M | 692,538 | 1.0% |
| Caris Life Sciences Inc(CAI) | COM | 142152107 | $18.5M | 687,500 | 1.0% |
| Zenas Biopharma Inc(ZBIO) | COM | 98937L105 | $18.2M | 502,077 | 0.9% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $17.9M | 912,955 | 0.9% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $17.8M | 125,500 | 0.9% |
| Pharvaris N V(PHVS) | COM | N69605108 | $17.3M | 623,402 | 0.9% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $15.5M | 427,596 | 0.8% |
| Phreesia Inc(PHR) | COM | 71944F106 | $14.8M | 876,600 | 0.8% |
| ZAI LAB LTD(ZLAB) | ADR | 98887Q104 | $14.3M | 811,546 | 0.7% |
| Danaher Corporation(DHR) | COM | 235851102 | $14.1M | 61,500 | 0.7% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $13.5M | 40,800 | 0.7% |
| Ardelyx Inc(ARDX) | COM | 039697107 | $13.4M | 2,299,473 | 0.7% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $13.4M | 4,453,741 | 0.7% |
| Summit Therapeutics Inc(SMMT) | COM | 86627T108 | $12.4M | 710,000 | 0.6% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $12.3M | 798,405 | 0.6% |
| Inspire MED SYS Inc(INSP) | COM | 457730109 | $12.1M | 131,000 | 0.6% |
| Omada Health Inc(OMDA) | COM | 68170A108 | $11.7M | 740,000 | 0.6% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $11.4M | 247,053 | 0.6% |